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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.
71 study records (showing up to 30 per record type)
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Registered trial NCT06047145 Completed (results not assessed here)Evaluation of Soy Isoflavones on Skin Ageing ParametersCondition or outcome area: Skin Ageing
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Registered trial NCT06156449 Not completed: RecruitingEffect of Thyme Oil on Respiratory Symptoms and Hemodynamic Parameters in COPD PatientsCondition or outcome area: Patient Engagement2023-11-15 · Subject: She Xiang Cao; 麝香草; Thyme; Thymus Vulgaris · open the herb record · ClinicalTrials.gov
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Registered trial NCT02996786 Completed (results not assessed here)Effects of Danggui Buxue Tang on Blood Biochemical Parameters in Male Recreational RunnersCondition or outcome area: Sports Anemia|Inflammation|Oxidative Stress|Iron Deficiency|Hemolysis|Fatigue2016-10 · Subject: Dang Gui Bu Xue Tang; 当归补血汤; Danggui Buxue Decoction;Dang Gui Bu Xue Decoction · open the formula record · ClinicalTrials.gov
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Registered trial NCT00360048 Completed (results not assessed here)Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy VolunteersCondition or outcome area: Sepsis
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Registered trial NCT01828710 Completed (results not assessed here)Myo-inositol on Human Semen ParametersCondition or outcome area: Asthenozoospermia|Oligospermia2012-08 · Subject: Myoinositol; Inositol; inositol b; D-myo-inositol; D-Chiro-Inositol; cocositol; Chiro-inositol; inositol c; KS-00001292; TR-022051 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01560065 Phase 4 Completed (results not assessed here)Effect of Treatment With Myo-inositol on Human Semen Parameters in Patients Undergoing In Vitro Fertilization CyclesCondition or outcome area: Sperm Quality|OligoasthenospermiaSubject: Myoinositol; Inositol; inositol b; D-myo-inositol; D-Chiro-Inositol; cocositol; Chiro-inositol; inositol c; KS-00001292; TR-022051 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01514942 Phase 4 Completed (results not assessed here)Myo-inositol Versus D-chiro-inositol in the Treatment of Polycystic Ovary Syndrome and Insulin Resistance: Evaluation of Clinical, Metabolic, Endocrine and Ultrasound ParametersCondition or outcome area: PCOSSubject: Myoinositol; Inositol; inositol b; D-myo-inositol; D-Chiro-Inositol; cocositol; Chiro-inositol; inositol c; KS-00001292; TR-022051 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT03811977 Completed (results not assessed here)The Effect of 12-Week Dietary Intake of Lutein on Minimal Erythema Dose and Other Skin ParametersCondition or outcome area: Minimal Erythema Dose|Skin Viscoelasticity|Dermis Density2019-03-04 · Subject: Lutein; SMP1_000317; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-2-en-1-ol; SCHEMBL10029505; CHEBI:28838; NSC59193; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-1-cyclohex-2-enol; C08601; LMPR01070274; (1R,4R)-4-[18-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-3,7,12,16-tetramethyl-octadeca-1,3,5, · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT02544165 Completed (results not assessed here)Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) LevelsCondition or outcome area: Hemodynamic Instability|Skin and Subcutaneous Tissue Disorders2012-11 · Subject: Caffeine; NCGC00015208-02; DHCplus; KBio2_001781; W222402_ALDRICH; NINDS_000730; EINECS 200-362-1; Spectrum5_000423; BSPBio_001921; KBio1_000730 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT03839888 Completed (results not assessed here)Short Term Refractive and Ocular Parameter Changes After Topical AtropineCondition or outcome area: Myopia, Left Eye2015-01-01 · Subject: Atropine; LS-187855; L-Hyoscyamine; 8-methyl-8-azabicyclo oct-3-hydroxy-2-phenylpropanoate; hyoscyamine; atropine · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT04126720 Phase 1 Completed (results not assessed here)Effect of Adjunctive Systemic Vitamin E on Clinical Parameters and Salivary Total Antioxidant Capacity in Symptomatic Oral Lichen Planus Patients: Randomized-controlled Clinical TrialCondition or outcome area: Oral Lichen Planus2016-01-22 · Subject: Vitamin E; T1539_SIGMA; NSC 82623; (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol; (+-)-alpha-Tocopherol; BRN 0094012; 5,7,8-Trimethyltocol; (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-; T3634_SIGMA · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01782911 Completed (results not assessed here)Effect of Resveratrol on Metabolic Parameters and Oocyte Quality in PCOS PatientsCondition or outcome area: Androgen Profile|Inflammatory Markers|IVF Outcome2013-02-01 · Subject: Trans-Resveratrol; Resveratrol; (E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene; SRT501; AX8004672; DB02709; RP17549; NCGC00017352-05; NCGC00017352-13; NCGC00017352-19 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01481389 Completed (results not assessed here)The Effect of Theobromine on Blood Lipid Parameters in Healthy SubjectsCondition or outcome area: Cardiovascular Diseases2010-12 · Subject: Theobromine; KBio1_000611; Thesodate; DivK1c_000611; Theostene; NCGC00016023-02; Thesal; 2,6-Dihydroxy-3,7-dimethylpurine; CAS-83-67-0; NCGC00024123-04 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT04336891 Completed (results not assessed here)Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.Condition or outcome area: Hypoactive Sexual Desire Disorder|Vulvovaginal Disease|Menopause Related Conditions|Dyspareunia (Female Excluding Psychogenic)|Hypoestrogenism|Arousal Disorders, Sexual2019-03-20 · Subject: Testosterone; SR-05000001542-1; Spectrum4_000114; AB00053134_04; KBioSS_001813; Spectrum2_001799; HMS2091C05; IDI1_000744; KBioGR_000468; Spectrum_001333 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01503359 Phase 2 Completed (results not assessed here)Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in SchizophreniaCondition or outcome area: Schizophrenia2012-01 · Subject: Sarcosine; N-Methylglycine, sodium salt · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT04499131 Phase 4 Not completed: RecruitingImpact of Different Doses and Routes of Exogenous Progesterone Administration on Endometrial Receptivity ParametersCondition or outcome area: Infertility, Female|ENDOMETRIAL RECEPTIVITY2021-12-09 · Subject: Progesterone; Cyclogesterin; Luteovis; Progeffik; (8S,9S,10R,13S,14S,17S)-17-ethanoyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; Gesterol 50; Corlutin; Syngestrets; NCGC00090798-02; D4-Pregnene-3,20-dione · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01754792 Completed (results not assessed here)Effects of Pinitol on Hidrocarbonated Metabolism Parameters in Diabetic, Impaired and Normal Fasting Glucose SubjectsCondition or outcome area: Type 2 Diabetes|Impaired Glucose Tolerance|Healthy2012-01 · Subject: Pinitol; (1R,2R,4R,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol; ZINC3978754; ZINC242463987; ononitol · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01738763 Completed (results not assessed here)Effects of Different Doses of Pinitol on Carbohydrate Metabolism Parameters in Healthy SubjectsCondition or outcome area: Healthy|Insulin Sensitivity2011-07 · Subject: Pinitol; (1R,2R,4R,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol; ZINC3978754; ZINC242463987; ononitol · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT02996513 Completed (results not assessed here)Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) MethodCondition or outcome area: Vitamin A Deficiency|Malaria|Inflammation2016-10 · Subject: Oleovitamin A; Retinol; Bentavit A; I14-19488; Avitol; 17104-91-5; Dofsol; all-trans-Vitamin A1; IDI1_000486; FPIPGXGPPPQFEQ-OVSJKPMPSA-N · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT04867252 Phase 2 Completed (results not assessed here)Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian SyndromeCondition or outcome area: PCOS2021-05-03 · Subject: Trans-Resveratrol; Resveratrol; (E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene; SRT501; AX8004672; DB02709; RP17549; NCGC00017352-05; NCGC00017352-13; NCGC00017352-19 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT04867252 Phase 2 Completed (results not assessed here)Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian SyndromeCondition or outcome area: PCOS2021-05-03 · Subject: Myoinositol; Inositol; inositol b; D-myo-inositol; D-Chiro-Inositol; cocositol; Chiro-inositol; inositol c; KS-00001292; TR-022051 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT03763669 Completed (results not assessed here)Myoinositol Supplementation, Insulin Resistance and Fetal Sonographic Parameters in Gestational Diabetes Diet TreatedCondition or outcome area: Gestational Diabetes2018-11-14 · Subject: Myoinositol; Inositol; inositol b; D-myo-inositol; D-Chiro-Inositol; cocositol; Chiro-inositol; inositol c; KS-00001292; TR-022051 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT03404011 Completed (results not assessed here)Acute Effects of Propylene Glycol/Glycerol Intake on Blood ParametersCondition or outcome area: Metabolic Complication2018-01-15 · Subject: IFP; Glycerol; 49771_FLUKA; Unigly G 2; InChI=1/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H; D-glycerol; 25618-55-7; Synthetic glycerine; L-glycerol; G1901_SIGMA · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT03020719 Phase 2 Completed (results not assessed here)The Role of Oral Glutathione on Growth Parameters in Children With Cystic FibrosisCondition or outcome area: Cystic Fibrosis
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Registered trial NCT01173107 Phase 4 Completed (results not assessed here)A Pilot Study for PK/PD Parameter of Colchicine in Chronic Kidney Disease Patient.Condition or outcome area: Chronic Kidney Disease
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Registered trial NCT04642131 Not completed: SuspendedEffect of Caffeine Supplementation and Personalized Insoles on FemalesCondition or outcome area: Caffeine|Fatigue|Injuries|Females Xy|Soccer|Biomechanical Parameters2020-12-09 · Subject: Caffeine; NCGC00015208-02; DHCplus; KBio2_001781; W222402_ALDRICH; NINDS_000730; EINECS 200-362-1; Spectrum5_000423; BSPBio_001921; KBio1_000730 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT03899675 Completed (results not assessed here)Impact of Caffeine Intake on Autonomic Parameters in the Exercise of StrengthCondition or outcome area: Autonomic Nervous System|Cardiovascular Outcomes2018-12-19 · Subject: Caffeine; NCGC00015208-02; DHCplus; KBio2_001781; W222402_ALDRICH; NINDS_000730; EINECS 200-362-1; Spectrum5_000423; BSPBio_001921; KBio1_000730 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT02256813 Phase 1 Completed (results not assessed here)Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male VolunteersCondition or outcome area: Healthy2005-09 · Subject: Caffeine; NCGC00015208-02; DHCplus; KBio2_001781; W222402_ALDRICH; NINDS_000730; EINECS 200-362-1; Spectrum5_000423; BSPBio_001921; KBio1_000730 · open the ingredient record · ClinicalTrials.gov
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Registered trial NCT01421979 Completed (results not assessed here)Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in HumansCondition or outcome area: Cardiovascular Risk
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Registered trial NCT01421979 Completed (results not assessed here)Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in HumansCondition or outcome area: Cardiovascular Risk2011-04 · Subject: Caffeine; NCGC00015208-02; DHCplus; KBio2_001781; W222402_ALDRICH; NINDS_000730; EINECS 200-362-1; Spectrum5_000423; BSPBio_001921; KBio1_000730 · open the ingredient record · ClinicalTrials.gov
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Systematic review registration CRD42023492979 Registered protocol, no results here: Review OngoingThe Effects of Vitamin D Supplementation on Renal Function and Bone Metabolic Parameters in Children and Young Adults with Chronic Kidney Disease: A Systematic Review and Meta AnalysisCondition or outcome area: Chronic kidney disease (CKD) is related to bone metabolism disorders including vitamin D deficiency, hypocalcaemia, hyperphosphatemia, and hyperparathyroidism. Vitamin D deficiency is common in chronic kidney disease. Vitamin D is not only important in bone metabolism, but also plays important roles as anti-inflammation, anti-fibrosis, immunomodulator, and anti-tumor. Some guidelines recommended routine measurement of serum 25(OH)D levels and maintaining vitamin D sufficiency. This study aims to2023-12-25 · Subject: Vitamin d; 24,25-Dihydroxyvitamin D; (3R,6R)-6-[(1R,3aS,7aR)-4-[2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5R)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; 24,25-dihydroxyvitamin D3; 24,25-Dihydroxycholecalciferol; 24,25-dihydroxyvitamin; CHEBI:89324; Q27161510; (3b,5Z,7E)-9,10-Secocholesta-5, · open the ingredient record
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Systematic review registration CRD42023448069 Registered protocol, no results here: Review OngoingA Systematic Review and Meta-Analysis of the Impact of Resveratrol on Oral Cancer: Potential Therapeutic ImplicationsCondition or outcome area: The present study aims to investigate the impact of resveratrol on oral neoplastic parameters through a systematic review and meta-analysis.2023-08-05 · Subject: Trans-resveratrol; Resveratrol; resveratrol; 501-36-0; 3,4',5-Trihydroxystilbene; (E)-5-(4-Hydroxystyryl)benzene-1,3-diol; 3,5,4'-Trihydroxystilbene; (E)-resveratrol; Resvida; 3,4',5-Stilbenetriol · open the ingredient record
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Systematic review registration CRD42023421263 Registered protocol, no results here: Review OngoingA systematic review and meta-analysis of the resveratrol effects on metabolic parameters of PCOS patientsCondition or outcome area: Women with polycystic ovary syndrome2023-05-05 · Subject: Trans-resveratrol; Resveratrol; resveratrol; 501-36-0; 3,4',5-Trihydroxystilbene; (E)-5-(4-Hydroxystyryl)benzene-1,3-diol; 3,5,4'-Trihydroxystilbene; (E)-resveratrol; Resvida; 3,4',5-Stilbenetriol · open the ingredient record
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Systematic review registration CRD42023471412 Registered protocol, no results here: Review OngoingEfficiency of silymarin on direct and indirect parameters of nonalcoholic fatty liver disease.Condition or outcome area: non-alcoholic fatty liver disease2023-10-21 · Subject: Silymarin; Silybin; 65666-07-1; Legalon; 84604-20-6; (2R,3R)-3,5,7-trihydroxy-2-[(2R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one; Silibin; 142796-20-1; 36804-17-8; Apihepar · open the ingredient record
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Systematic review registration CRD42023409554 Registered protocol, no results here: Review OngoingThe effects of selenium supplementation on glycemic parameters in adults: A systematic review and dose-response meta-analysisCondition or outcome area: Healthy, overweight or obese individuals, and those with any metabolic non-communicable disease such ascardiovascular disorders dyslipidemia, hypercholesterolemia, metabolic syndrome2023-03-31 · Subject: Se; Selenium; 7782-49-2; Elemental selenium; SELENIUM ATOM; Selenium, elemental; Selenium hydride; Selenium elemental; Gray selenium; Selenium, metallic · open the ingredient record
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Systematic review registration CRD42023400806 Registered protocol, no results here: Review Completed publishedPhthalate exposure and the metabolic syndrome: a systematic review and meta-analysisCondition or outcome area: Metabolic syndrome is included as a risk factor for cardiovascular disease, diabetes, and others. Is a group of conditions that includes parameters on body weight/abdominal circumference, blood pressure, blood glucose level, blood tryglicerides, and HDL-cholesterol2023-03-01 · Subject: Phthalate; 3198-29-6; benzene-1,2-dicarboxylate; phthalate(2-); z phthalate; 3c2r; 1,2-benzenedicarboxylate; 1,2-Benzenecarboxylic acid; CHEBI:17563; DTXSID10185812 · open the ingredient record
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Systematic review registration CRD42023437596 Registered protocol, no results here: Review OngoingThe effectiveness of four commonly used oral nutraceuticals in improving the Sperm quality in male infertility: a network Meta-analysis of Randomized Controlled TrialsCondition or outcome area: Infertility is defined as being unable to conceive after 12 months of regular (at least twice weekly) unprotected intercourse . Male infertility is due to abnormal sperm parameters in the male partner and are estimated to be present in about 50% of cases . Insulin resistance has been recognized as a key contributor to the disease since infertile men are closely related to the occurrence of metabolic syndrome and diabetes . Currently, certain nutraceuticals such as coenzyme Q10 (CoQ10), vitamin E2023-06-29 · Subject: Vitamin e; Alpha-Tocopherol; alpha-Tocopherol; 59-02-9; D-alpha-Tocopherol; 5,7,8-Trimethyltocol; (+)-alpha-Tocopherol; 2074-53-5; alpha Tocopherol; Phytogermine · open the ingredient record
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Systematic review registration CRD42023437596 Registered protocol, no results here: Review OngoingThe effectiveness of four commonly used oral nutraceuticals in improving the Sperm quality in male infertility: a network Meta-analysis of Randomized Controlled TrialsCondition or outcome area: Infertility is defined as being unable to conceive after 12 months of regular (at least twice weekly) unprotected intercourse . Male infertility is due to abnormal sperm parameters in the male partner and are estimated to be present in about 50% of cases . Insulin resistance has been recognized as a key contributor to the disease since infertile men are closely related to the occurrence of metabolic syndrome and diabetes . Currently, certain nutraceuticals such as coenzyme Q10 (CoQ10), vitamin E2023-06-29 · Subject: Vitamin d; 24,25-Dihydroxyvitamin D; (3R,6R)-6-[(1R,3aS,7aR)-4-[2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5R)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; 24,25-dihydroxyvitamin D3; 24,25-Dihydroxycholecalciferol; 24,25-dihydroxyvitamin; CHEBI:89324; Q27161510; (3b,5Z,7E)-9,10-Secocholesta-5, · open the ingredient record
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Systematic review registration CRD42023437596 Registered protocol, no results here: Review OngoingThe effectiveness of four commonly used oral nutraceuticals in improving the Sperm quality in male infertility: a network Meta-analysis of Randomized Controlled TrialsCondition or outcome area: Infertility is defined as being unable to conceive after 12 months of regular (at least twice weekly) unprotected intercourse . Male infertility is due to abnormal sperm parameters in the male partner and are estimated to be present in about 50% of cases . Insulin resistance has been recognized as a key contributor to the disease since infertile men are closely related to the occurrence of metabolic syndrome and diabetes . Currently, certain nutraceuticals such as coenzyme Q10 (CoQ10), vitamin E2023-06-29 · Subject: Myoinositol; Inositol; inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; 87-89-8 · open the ingredient record
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Systematic review registration CRD42023472889 Registered protocol, no results here: Review OngoingAdjunctive use of melatonin in intraosseous defects as part of step 2 periodontal therapy: systematic review, meta-analysisCondition or outcome area: This systematic review and meta-analysis will aim to compare people who received adjuvant administered Melatonin therapy for intraosseous defects and have better clinical parameters compared to patients who did not receive it?2023-10-29 · Subject: Melatonin; 73-31-4; Melatonine; N-Acetyl-5-methoxytryptamine; Circadin; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide; 5-Methoxy-N-acetyltryptamine; N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide; Melatol; Melovine · open the ingredient record
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Systematic review registration CRD42023409151 Registered protocol, no results here: Review OngoingA systematic review and meta-analysis of the Melatonin effects on metabolic parameters of PCOS patientsCondition or outcome area: Women with polycystic ovary syndrome2023-03-29 · Subject: Melatonin; 73-31-4; Melatonine; N-Acetyl-5-methoxytryptamine; Circadin; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide; 5-Methoxy-N-acetyltryptamine; N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide; Melatol; Melovine · open the ingredient record
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Systematic review registration CRD42023413237 Registered protocol, no results here: Review OngoingEffect of Magnesium Sulfate on Doppler Parameters of Fetal Arteries: A Systematic Review and Meta-AnalysisCondition or outcome area: Magnesium sulfate (MgSO4) is used as a fetal neuroprotection in preterm labor, a prophylactic agent for seizure in preeclampsia, and a tocolytic agent in preterm labor and can help prevent serious complications in pregnancy. However, the effect of magnesium sulfate (MgSO4) on fetal Middle Cerebral (MCA) and umbilical vessels is still controversial, and it is unclear whether it reduces cerebrovascular events. The aim of this study was to assess the effect of MgSO4 on the fetal middle cerebral Dop2023-04-25 · Subject: Magnesium sulfate; Magnesium Sulfate; 7487-88-9; Magnesium sulphate; Magnesium sulfate anhydrous; MgSO4; Magnesium sulfate (1:1); Magnesiumsulfat; Sal Angalis; Sal De sedlitz · open the ingredient record
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Systematic review registration CRD42023420962 Registered protocol, no results here: Review OngoingA systematic review and meta-analysis on the effect of lycopene antioxidant on semen parameters visualized for idiopathic male infertilityCondition or outcome area: Idiopathic Male infertility2023-05-06 · Subject: Lycopene; 502-65-8; all-trans-Lycopene; Psi,psi-carotene; trans-Lycopene; Lycopene 7; lycored; Redivivo; Mexoryl SAQ; Tomat-O-Red · open the ingredient record
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Systematic review registration CRD42023413975 Registered protocol, no results here: Review OngoingCan exposure to mercury compromise male reproductive parameters? A systematic review.2023-10-11 · Subject: Hydrargyrum; Mercury; 7439-97-6; Hg; Quicksilver; Metallic mercury; Liquid silver; Quecksilber; Mercure; Mercurio · open the ingredient record
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Systematic review registration CRD42023432461 Registered protocol, no results here: Review OngoingEffect of Magnesium Sulfate on Doppler Parameters of Neonatal Arteries: A Systematic Review and Meta- AnalysisCondition or outcome area: Magnesium sulfate (MgSO4) is used as a fetal neuroprotection in preterm labor, a prophylactic agent for seizure in preeclampsia, and a tocolytic agent in preterm labor and can help prevent serious complications in pregnancy. However, the effect of magnesium sulfate (MgSO4) on the Middle and Anterior Neonatal Cerebral Arteries (MCA & ACA) and Upper Mesenteric Arteries is still controversial. Some studies have described a marginal, neuroprotective effect of MgSO4 in the newborn as well as on n2023-06-18 · Subject: Magnesium sulfate; Magnesium Sulfate; 7487-88-9; Magnesium sulphate; Magnesium sulfate anhydrous; MgSO4; Magnesium sulfate (1:1); Magnesiumsulfat; Sal Angalis; Sal De sedlitz · open the ingredient record
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Systematic review registration CRD42023422189 Registered protocol, no results here: Review OngoingA systematic review and meta-analysis of the Alpha-Lipoic Acid effects on metabolic parameters of PCOS patientsCondition or outcome area: Women with polycystic ovary syndrome2023-05-08 · Subject: Alpha-lipoic acid; Thioctic acid; thioctic acid; dl-Thioctic acid; 1077-28-7; 5-(1,2-Dithiolan-3-yl)pentanoic acid; DL-alpha-Lipoic acid; 1,2-dithiolane-3-pentanoic acid; alpha Lipoic Acid; Biletan · open the ingredient record
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Systematic review registration CRD42023436899 Registered protocol, no results here: Review OngoingThe effect of Flaxseed on lipid profile parameters: A systematic review and meta-analysisCondition or outcome area: patients with different disease
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Systematic review registration CRD42023458119 Registered protocol, no results here: Review OngoingAssessing the effect of Saffron (Crocus sativus L.) supplementation on oxidative stress, inflammatory indices, renal and liver functional parameters in patients with prediabetes and type 2 diabetes mellitus: A GRADE-assessed systematic review and meta-analysis of Randomized Clinical TrialsCondition or outcome area: Diabetes mellitus (DM) is a group of endocrine metabolic diseases that is widespread worldwide and is a major public health concern in the world. It has been estimated that 5–10 % of individuals with prediabetes develop type 2 diabetes mellitus (T2DM) annually. DM has side effects on several organs such as heart, kidney, eye and nerve cells, and causes complications and affect the quality of life of patients. Hyperglycemia and hypertension are the most important complications of diabetes. Theref
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Systematic review registration CRD42023444596 Registered protocol, no results here: Review OngoingEffect of Pomegranate Seed Oil Supplementation on Cardiometabolic Parameters: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsCondition or outcome area: Cardiometabolic disorders, such as metabolic syndrome, diabetes mellitus, hypertension, dyslipidemia, fatty liver, and cardiovascular disease, can have grave outcomes and are linked to higher rates of mortality and morbidity as well as significant social expenses globally. Extensive documentation supports the positive impacts of nutritional compounds containing antioxidant and anti-inflammatory properties in preventing and treating cardiometabolic disorders.2023-07-22 · Subject: Shi Liu Zhong Zi; 石榴种子; Pomegranate Seed; Punica Granatum · open the herb record
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Systematic review registration CRD42023465688 Registered protocol, no results here: Review OngoingInvestigating the Ginseng Supplementation on Cardiovascular Disease Risk Factors: a Systematic Review and Meta-analysisCondition or outcome area: The research will center on investigating the influence of ginseng supplementation on a range of health indicators within a specified field or scope. In particular, the study will focus on examining the impact of ginseng supplementation on anthropometric measurements, which will encompass various parameters such as weight and body mass index. Additionally, the investigation will aim to elucidate the effects of ginseng supplementation on blood pressure levels, glycemic indices (specifically blood2023-10-02 · Subject: Ren Shen; 人参; Ginseng ; Ginseng; Radix et Rhizoma Ginseng; Ginseng Radix et Rhizoma · open the herb record
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Systematic review registration CRD42023412335 Registered protocol, no results here: Review OngoingEfficacy of Oral Aloe Vera Supplementation on Skin wrinkles, Hydration, Elasticity, Transepidermal Water Loss and Collagen Score: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsCondition or outcome area: Wrinkles are major features of aging; and skin hydration, skin elasticity, transepidermal water loss (TEWL), and collagen score are some parameters used in measuring the skin’s resilience to wrinkles. Orally administered aloe vera supplements have shown promise in alleviating some of these skin aging parameters. To determine the effects of oral aloe vera supplements on skin wrinkles, hydration, elasticity, TEWL, and collagen score compared with placebo or no treatment.
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Systematic review registration CRD42023484490 Registered protocol, no results here: Review OngoingEffect of Cocoa Consumption on Cardiometabolic Risk Parameters: protocol for a systematic review and meta-analysis of randomized controlled trialsCondition or outcome area: Cardiovascular Risk parameters: Type 2 diabetes. Hypercholesterolemia, High Tryglicerides, Hypertension, Elderly
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Systematic review registration CRD42023426254 Registered protocol, no results here: Review OngoingEffect of Garcinia mangostana extract on blood glucoses and other parameters in diabetes mellitus: a systematic review and meta-analysis
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Systematic review registration CRD42023425641 Registered protocol, no results here: Review OngoingEffect of Mucuna pruriens on male infertility: A systematic review and meta-analysisCondition or outcome area: Male infertility is a medical condition that affects a significant proportion of couples trying to conceive. It is characterized by the inability of a man to contribute to conception despite frequent unprotected sexual intercourse with their partner. Semen analysis is a critical diagnostic tool for assessing male fertility potential, which includes the evaluation of various semen parameters such as sperm count, motility, morphology, and volume. Understanding the causes and factors that contribut2023-05-27 · Subject: Ci Mao Li Dou; 刺毛黧豆; Cowage Velvet-Bean; Mucuna Pruriens · open the herb record
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Systematic review registration CRD42023420489 Registered protocol, no results here: Review OngoingEffect of carob (Ceratonia siliqua) on sperm characteristics of infertile men: A systematic review and meta-analysisCondition or outcome area: Infertile men aged 20-65 years who use carob to improve sperm parameters and testicular function (regardless of duration of treatment).
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Systematic review registration CRD42023421339 Registered protocol, no results here: Review OngoingEffect of Cynara scolymus L. on cardiometabolic outcomes: An update meta-analysis of randomizedcontrolled trials and meta-regressionCondition or outcome area: 1. Blood glucose outcomes including fasting plasma glucose (FPG), HbA1C and Homeostasis model assessment of insulin resistance (HOMA-IR) of participants who use Cynara scolymus products. 2. Lipid profiles outcomes including LDL, HDL, triglyceride (TG), total cholesterol (TC) of participants who use Cynara scolymus products. 3. Blood pressure including systolic blood pressure (SBP) and diastolic blood pressure (DBP) of participants who use Cynara scolymus products. 4. Anthropometric parameters in
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Systematic review registration CRD42022299343 Registered protocol, no results here: Review OngoingEffect of Vitamin D Supplementation to Parameter of Sarcopenia in Elderly PeopleCondition or outcome area: Vitamin D is important for muscle metabolism, and insufficiency has been linked to an increased risk of sarcopenia. However, the precise effect of vitamin D supplementation on the parameter of sarcopenia (muscle mass, muscle strength, and physical performance) has yet to be determined.2022-01-19 · Subject: Vitamin d; 24,25-Dihydroxyvitamin D; (3R,6R)-6-[(1R,3aS,7aR)-4-[2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5R)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; 24,25-dihydroxyvitamin D3; 24,25-Dihydroxycholecalciferol; 24,25-dihydroxyvitamin; CHEBI:89324; Q27161510; (3b,5Z,7E)-9,10-Secocholesta-5, · open the ingredient record
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Systematic review registration CRD42021243315 Registered protocol, no results here: Review OngoingCould supplementary treatment with vitamin D in rheumatoid arthritis patients promote alterations in systemic immunological parameters? A Systematic ReviewCondition or outcome area: Rheumatoid Arthritis (RA) is a chronic autoimmune disease in which inflammation causes destruction of articular tissue, with systemic pain and function loss of one or more articulations. It is a multifactorial pathology in which characteristics such as genetics, gender (three times more likely to occur in women than in men), infections from certain microorganisms and smoking all contribute to its development. RA’s pathophysiology is characterized by the action of T and B autoreactive lymphocytes2021-06-21 · Subject: Vitamin d; 24,25-Dihydroxyvitamin D; (3R,6R)-6-[(1R,3aS,7aR)-4-[2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5R)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; 24,25-dihydroxyvitamin D3; 24,25-Dihydroxycholecalciferol; 24,25-dihydroxyvitamin; CHEBI:89324; Q27161510; (3b,5Z,7E)-9,10-Secocholesta-5, · open the ingredient record
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Systematic review registration CRD42020155847 Registered protocol, no results here: Review Completed publishedVitamin D supplementation in patients with cystic fibrosis: A systematic review and meta-analysis.Condition or outcome area: A significant proportion of patients with cystic fibrosis are vitamin D deficient which can be a major contributor to bone disease. The current vitamin D supplementation practice of these patients is based on consensus only and the benefits of this intervention are not clear. Recent years' publications suggest a positive effect on respiratory parameters and immunological status as well but with conflicting results - warranting a quantitative synthesis of high-evidence publications.2020-04-28 · Subject: Vitamin d; 24,25-Dihydroxyvitamin D; (3R,6R)-6-[(1R,3aS,7aR)-4-[2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5R)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol; 24,25-dihydroxyvitamin D3; 24,25-Dihydroxycholecalciferol; 24,25-dihydroxyvitamin; CHEBI:89324; Q27161510; (3b,5Z,7E)-9,10-Secocholesta-5, · open the ingredient record
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Systematic review registration CRD42020152032 Registered protocol, no results here: Review OngoingVitamin K and Polycystic Ovary Syndrome: effect of vitamin K status /supplementation on hormonal and metabolic parametersCondition or outcome area: • Polycystic ovary syndrome (PCOS) is one of the commonest endocrine disorders in women in reproductive age. Despite its higher prevalence (6-10% in menacme), many aspects regarding the development and consequences of PCOS are still unknow. Recent evidence from the literature has point out a role of Vitamin K in the development of cardio-metabolic diseases, in particular, insulin resistance, atherosclerosis and glucose control in the general population and diabetic patients. Some studies also su2020-03-13 · Subject: Vitamin k; Vitamin K; 12001-79-5; 81818-54-4; Kephton; 2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione; Vitamin K1(20); .alpha.-Phylloquinone; 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-en-1-yl)naphthalene-1,4-dione; 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)naphthalene-1,4-dione · open the ingredient record
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Publication PMID 33166511 Research model: Animal ExperimentRecovery of brain cholinesterases and effect on parameters of oxidative stres and apoptosis in quails (Coturnix japonica) after chlorpyrifos and vitamin B1 administrationCondition or outcome area: B-cell lymphomaChem Biol Interact · 2021 · Subject: Vitamin b1; vitamin B1; 59-43-8; Thiamine chloride; Thiamine monochloride; Aneurine; Vitaneurin; Bethiamin; Oryzanin; Beivon · open the ingredient record · DOI 10.1016/j.cbi.2020.109312
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Publication PMID 33068743 Research model: Animal ExperimentEffect of resveratrol on behavioral, biochemical, and immunological parameters of DBA/2J and tetrahybrid DBCB mice receiving diet with excess fat and fructoseCondition or outcome area: obesity; dyslipidemiaJ Nutr Biochem · 2021 · Subject: Trans-resveratrol; Resveratrol; resveratrol; 501-36-0; 3,4',5-Trihydroxystilbene; (E)-5-(4-Hydroxystyryl)benzene-1,3-diol; 3,5,4'-Trihydroxystilbene; (E)-resveratrol; Resvida; 3,4',5-Stilbenetriol · open the ingredient record · DOI 10.1016/j.jnutbio.2020.108527
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Publication PMID 33785337 Research model: Animal ExperimentModulatory effects of caffeic acid on purinergic and cholinergic systems and oxi-inflammatory parameters of streptozotocin-induced diabetic ratsCondition or outcome area: Diabetes mellitus; metabolic disorder; Diabetes; diabetic; hyperglycemiaLife Sci · 2021 · Subject: Trans-caffeic acid; Caffeic Acid; caffeic acid; 3,4-Dihydroxycinnamic acid; 331-39-5; 501-16-6; 3-(3,4-dihydroxyphenyl)acrylic acid; 3,4-Dihydroxybenzeneacrylic acid; (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid; 3-(3,4-Dihydroxyphenyl)-2-propenoic acid · open the ingredient record · DOI 10.1016/j.lfs.2021.119421
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Publication PMID 34139304 Research model: Animal ExperimentOn the mechanisms of taurine in alleviating electrocardiographic, hemodynamic, and biochemical parameters following aluminum phosphide cardiotoxicityCondition or outcome area: cardiotoxicity; AlP poisoning; cardiac injuriesFood Chem Toxicol · 2021 · Subject: Tatarine; Taurine; taurine; 2-aminoethanesulfonic acid; 107-35-7; Ethanesulfonic acid, 2-amino-; tauphon; L-Taurine; 2-Aminoethylsulfonic acid; 2-Sulfoethylamine · open the ingredient record · DOI 10.1016/j.fct.2021.112347
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Publication PMID 32914418 Research model: Cell ExperimentThe effects of malvidin on oxidative stress parameters and inflammatory cytokines in LPS-induced human THP-1 cellsCondition or outcome area: acute monocytic leukemia; inflammatory diseasesJ Cell Physiol · 2021 · Subject: Malvidin; 10463-84-0; CHEBI:6674; 3',5'-Dimethoxy-3,4',5,7-tetrahydroxyflavylium acid anion; 2-(4-hydroxy-3,5-dimethoxyphenyl)chromenylium-3,5,7-triol; BRN 1691742; .malvidin; Benzopyrylium, 3 5,7-trihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-, acid anion; SCHEMBL21739; 3,5,7,4'-tetrahydroxy-3',5'-dimethoxyflavylium · open the ingredient record · DOI 10.1002/jcp.30049
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Publication PMID 31926565 Research model: Animal ExperimentAttenuation of sleep deprivation dependent deterioration in male fertility parameters by vitamin CReprod Biol Endocrinol · 2020 · Subject: L-ascorbic acid; Ascorbic Acid; ascorbic acid; vitamin C; 50-81-7; L-ascorbate; Ascoltin; ascorbate; Ascorbicap; Cevitamic acid · open the ingredient record · DOI 10.1186/s12958-020-0563-y
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Publication PMID 34792730 Research model: Animal ExperimentInvestigating the Effect of Inosine on Brain Purinergic Receptors and Neurotrophic and Neuroinflammatory Parameters in an Experimental Model of Alzheimer's DiseaseCondition or outcome area: memory deficits; Alzheimer's disease; impairment of memory; neurodegenerative pathologyMol Neurobiol · 2022 · Subject: Inosine; 58-63-9; Hypoxanthosine; Ribonosine; Atorel; Oxiamin; Hypoxanthine riboside; Trophicardyl; Selfer; Pantholic-L · open the ingredient record · DOI 10.1007/s12035-021-02627-z
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Publication PMID 35178811 Research model: Clinical ExperimentEffects of curcumin supplementation on metabolic parameters, inflammatory factors and obesity values in women with rheumatoid arthritis: A randomized, double-blind, placebo-controlled clinical trialCondition or outcome area: obesity; Rheumatoid arthritis; chronic inflammatory disease; cartilage damage; metabolic disordersPhytother Res · 2022 · Subject: Curcumin; 458-37-7; Diferuloylmethane; Natural yellow 3; Kacha haldi; Indian saffron; Curcuma; Gelbwurz; Haldar; Curcumin I · open the ingredient record · DOI 10.1002/ptr.7422
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Publication PMID 34043992 Research model: Animal ExperimentProtective effect of apigenin on ethylene glycol-induced urolithiasis via attenuating oxidative stress and inflammatory parameters in adult male Wistar ratsCondition or outcome area: urolithiatic; urinary stones; hyperoxaluriaLife Sci · 2021 · Subject: Apigenin; 520-36-5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Versulin; Apigenol; Chamomile; 4',5,7-Trihydroxyflavone; Spigenin; Apigenine; C.I. Natural Yellow 1 · open the ingredient record · DOI 10.1016/j.lfs.2021.119641
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Publication PMID 33924791 Research model: Animal ExperimentPhysicochemical Properties and Effects of Fruit Pulps from the Amazon Biome on Physiological Parameters in RatsNutrients · 2021 · Subject: Dao Nian Zi; 倒捻子; Mangosteen; Garcinia Mangostana · open the herb record · DOI 10.3390/nu13051484
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Publication PMID 35605922 Research model: Animal ExperimentEffects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome in Wistar ratsCondition or outcome area: polycystic ovary syndrome; Polycystic ovary syndrome; endocrine disordersBiomed J · 2022 · Subject: Tu Jue Qiang Wei; 突厥蔷薇; Damask Rose; Rosa Damascena · open the herb record · DOI 10.1016/j.bj.2022.05.003