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Black truffle (Tuber) fruiting body
A black truffle: the underground fruiting body of a Tuber fungus.

Mushrooms · Culinary fungus

Chinese Truffle

Tuber indicum, Tuber himalayense (two names in use; they are listed as separate species) · also called Chinese black truffle, Asian black truffle, Asian truffle

Chinese truffle is a black truffle that grows underground in Asia and is sold at a lower price than the European Perigord truffle. It is eaten in small amounts for its smell, which papers describe as weaker. Scientists have shown that it can be passed off as the costly European truffle, so labels matter. There are no human health studies, only lab and mouse work.

General information, not medical advice. Last substantive update · Not medically reviewed. A named clinician has not signed off on this page. How this page is made

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About Chinese Truffle

Chinese truffle (Tuber indicum, sometimes called Tuber himalayense) is a black truffle from Asia, cheaper than the European Perigord truffle. Papers say it looks very like the Perigord truffle, has a weaker smell and has been passed off as it. There are no human studies of health effects; the research is about aroma, species tests and mouse and test-tube work.

Passed off as European truffle

The authors of a near-infrared study write that the costly Perigord truffle forms fruiting bodies very like those of Tuber indicum, so there is a risk of fraud through imported Asian truffles, and that beginners cannot tell truffles apart by sight. An aroma paper says Tuber indicum is exported to Europe and often used to counterfeit the Perigord truffle, and that it is coated with artificial truffle oil to imitate the smell. That last point is the authors' statement citing an earlier paper, which we did not open.

Lab methods can separate the two: near-infrared light (up to 100% accuracy in 126 truffles of four species), NMR (100% in 80 samples of five species) and sterol patterns. A shopper cannot do this. We found no survey measuring how often the swap happens, so we do not say how common it is. This is a money and labelling problem, not a poison risk. Orchard growers also report Tuber indicum slipping in when tree seedlings are inoculated.

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Which species is it?

Chinese black truffles belong to a group of look-alike species called the Tuber indicum complex. GBIF lists Tuber indicum and Tuber himalayense as two separate accepted species. A 2018 DNA study of 52 specimens treated T. formosanum as a synonym of T. himalayense, and another found two lineages in southwest China (Tuber cf. indicum and Tuber cf. himalayense).

We did not find a source saying which Latin name sellers print on the product, so 'Chinese truffle' on a label may cover more than one species. Tuber himalayense is also called the Asian black truffle, and a 2026 paper says its wild populations have declined since the 1990s from habitat loss and overharvesting.

17 6 13 7

Smell and grades

In 95 volatile compounds found across three commercial grades, the top grade had the most variety and the strongest odour activity, led by an ester (ethyl isobutyrate) and an alcohol (1-octen-3-ol). Another study of several species found the aroma intensity lowest in Tuber indicum. Smell is why truffles are sold, so weaker aroma is part of the price gap.

For the aroma chemistry of truffles in general and for truffle oil, see the page on truffles.

10 3

What the lab and mouse work shows

Lab-made polysaccharide fractions from Tuber indicum restored some T-cell and B-cell proportions and changed gut bacteria in mice whose immune systems were weakened by a cancer drug. One purified compound lowered inflammation signals in mouse cells and zebrafish. These findings are about extracts and isolated chemicals, not truffle as eaten.

A 2025 review states human trials of truffles remain absent. We therefore rate every health use very low or insufficient.

4 9 2

As a food

For Tuber indicum from China, a review lists roughly 52 to 80% carbohydrate, 13 to 23% protein and 2 to 7% fat by dry weight, with large differences between regions. A serving is tiny, so it is not a meaningful source of any nutrient. Truffles spoil fast, and freezing or drying changes the aroma.

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Truffle oil and sauces

In 18 Italian truffle-flavoured olive oils, 19 of 63 volatile compounds were attributed to truffle and 12 were foreign compounds of dubious origin. That study did not test Chinese truffle in particular. Check labels for whether the flavour is natural.

12 8

At a glance

Traditional uses history, not proof

  • Eaten as a lower-priced black truffle for aroma (papers read describe it as a food).
  • Older medicinal traditions were not read, so none is claimed here.

Studied for research

  • Aroma and grading, low (lab chemistry)
  • Immune markers in mice from extracted sugar chains, very low (animal only)
  • Antioxidant and anti-inflammatory activity, very low (test tube and cells)
  • Nutrients as a food, insufficient
  • Any human health effect, insufficient (no trials)

Main compounds

  • Aroma compounds: esters, 1-octen-3-ol and sulfur compounds
  • Polysaccharides (sugar chains) and sterols
  • Phenolics

Common forms

  • Fresh truffle, shaved or grated
  • Frozen or dried truffle
  • Truffle oil, sauces and pastes (often flavoured)
  • Laboratory extracts (research only)

Research links: Kappacher 2022: near-infrared tests that separate Chinese from Perigord truffle · Epping 2022: marker substances in truffle aroma · Luo 2025: aroma of Chinese black truffle by grade · Ji 2026: mouse study of Tuber indicum polysaccharides · Kinoshita 2018: naming in the Tuber indicum complex · Baldelli 2025 review: truffle compounds and antioxidants · Research Library · Genes & Biomarkers Library

What it is and its history

Accepted scientific name
Tuber indicum
Naming authority
Cooke & Massee, 1892 (GBIF)
Synonyms
Tuber himalayense B.C.Zhang & Minter is listed by GBIF as a separate accepted species; Kinoshita 2018 treats T. formosanum as a synonym of T. himalayense
Common names
Chinese truffle (English); Chinese black truffle (English); Asian black truffle (English); Asian truffle (English)
Family or group
Tuberaceae (a fungus family, not a plant)
Classification
Fungi > Ascomycota > Tuberaceae > Tuber > Tuber indicum; T. himalayense (separate species in GBIF)
Native range
Papers read place the T. indicum complex in China (southwest China per Qiao 2018) and T. himalayense in Asia, with one nursery cultivation in Japan.
Habitat
Underground fungi that grow with tree roots (ectomycorrhizal).
What it looks like
Fruiting body: An Epping 2022 passage describes the fruiting body as dark brown, with almost tasteless black-brown flesh with small white veins, and visually similar to T. melanosporum.
Cultivation
A 2026 paper reports the first successful cultivation of T. himalayense in Japan after 7.5 years. Details for T. indicum were not read.
Harvest and processing
Not checked beyond harvest from natural habitats in the 2026 T. himalayense paper.
Look-alikes and adulterants
Name: Tuber melanosporum (black Perigord truffle); Note: The costly European species it is said to be passed off as; lab methods can separate them.; Name: Other members of the T. indicum complex (T. himalayense, T. formosanum, T. longispinosum); Note: DNA studies show several lookalike lineages; a label may not say which one is inside.; Name: Psilocybe 'magic truffles'; Note: A different fungus and a different product; see /mushrooms/psilocybin-truffles.
Sustainability and conservation
A 2026 paper says wild T. himalayense populations have declined since the 1990s from habitat degradation and overharvesting.

Traditional use and history history, not clinical proof

Tradition or eraDocumented useSource
Modern gourmet cookingSold as a lower-priced black truffle; papers describe it being used to imitate costlier European black truffle.p36014409
Earlier history and traditional medicineNot read, so none is stated here.p41300498

Traditional use shows how it was used. It does not show that it works or is safe today.

What is inside, and how it may work

What it contains and how those compounds act in cells and animals. Laboratory and animal mechanisms are not proven effects in people.

Main compounds

CompoundFamilyWhere it is concentratedActivity studiedLevel of evidence
Volatile aroma compounds (esters such as ethyl isobutyrate, 1-octen-3-ol, sulfur compounds)aroma volatilesFruiting bodyGive the truffle its smell; 95 were found across three grades. 10Laboratory research
Polysaccharides (glucose-based sugar chains)polysaccharideFruiting body
Water-extracted fraction up to 2.65 x 10^7 Da and alkali-extracted up to 3.87 x 10^7 Da molecular weight in the mouse paper.
Changed immune-cell proportions and gut bacteria in mice. 4Animal research
Sterols (ergosterol, brassicasterol and minor sterols)sterolFruiting bodyPattern of minor sterols tells European from Chinese truffles. 14Laboratory research
PhenolicsphenolicFruiting body
Folin-Ciocalteu total phenolics roughly 1 to 2 mg gallic acid equivalents per g dry matter in a comparison of three black truffles, per the review.
Linked to lab antioxidant activity. 2Laboratory research

Mechanisms, receptors and pathways

Target or pathwayGene or receptorWhat was foundLevel
Immune-cell proportions and gut bacteria (animal)CD3+ T cells, CD19+ B cellsPolysaccharide fractions restored the proportions in mice given cyclophosphamide and enriched Lactobacillus. 4Animal research
PI3K / Akt pathway (cells)PI3K, Akt, PTENOne isolated compound lowered p-PI3K and p-Akt and raised p-PTEN in mouse macrophages. 9Laboratory research

Absorption, metabolism and elimination

Absorption
Not found in the sources read.
Distribution
Not found.
Metabolism
Not found.
Elimination
Not found.
Bioavailability
Not established.

2

Isolated compounds versus whole extracts

Eating fresh truffle in tiny amounts is a food use. Lab findings come from purified polysaccharides or single compounds, which are not the food. Truffle oils and pastes may contain truffle, added aroma or both.

Nutritional composition

Dry-weight ranges for T. indicum from China in a 2025 review: carbohydrate 52 to 80%, protein 13 to 23%, fat 2 to 7%. These are quoted from other papers and vary by region.

6benefits and uses looked at
17studies and sources checked
Low certaintybest evidence rating found
0lab markers tracked in trials

1 low certainty3 very low certainty2 not enough evidence

What was looked at

The 6 benefits and uses checked for Chinese Truffle, each with how strong the evidence is. Tap one to open it.

Benefits, one by one

Each card is a research question, not a promise. Tap a goal to filter. Open a card to see the studies, doses and limits.

Aroma and grading (the real use)

Low certainty

Chinese truffle is eaten for its smell, but it is the weaker-smelling truffle. One lab study found its aroma weakest among the species it tested. Another found that top-grade Chinese truffles had a richer mix of aroma compounds than lower grades.

2 studiesEaten fresh in small amounts as flavouring.

Studies, doses and limits

What the trials found

This is food chemistry, not a health effect. In 95 volatile compounds across three commercial grades, the top grade had the most variety (75) and the strongest odour activity, led by ethyl isobutyrate and 1-octen-3-ol. A separate study of several species found aroma lowest in T. indicum.

Results

Top grade: 75 of 95 volatile compounds; aroma intensity lowest in T. indicum among the species in one study.

Effect sizes as reported

Aroma difference between grades measured; no health outcome

Why this rating

One grading study and one comparison study; numbers of samples were not given in the abstracts.

Form and dose studied

Eaten fresh in small amounts as flavouring.

Who was studied

Chinese black truffle, fresh fruiting bodies

Limits

Lab chemistry only. A smell is not a health benefit.

Why researchers looked

Aroma is why truffles are bought. Chemists test whether smell can be used to grade Chinese truffles by quality and tell them from other species.

Traditional use

Eaten as a gourmet food. The sources read describe it as a food, not a remedy.

Proposed mechanism Laboratory research

Esters, alcohols such as 1-octen-3-ol and sulfur compounds drive smell in lab measurements.

A proposed mechanism does not show that the effect happens in people.

Eating truffle as flavouring has no known harm in the sources read; see the Safety tab for allergy and fake-product points.

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Immune system (mouse study of extracted sugar chains)

Very low certainty

Sugar chains (polysaccharides) extracted from Chinese truffle in the lab brought back some white blood cell proportions in mice whose immune systems had been weakened by a cancer drug. This does not show that eating truffle helps human immunity.

1 studiesLab-made polysaccharide fractions given to mice; not a food or supple…

Studies, doses and limits

What the trials found

No human study was found. In mice given cyclophosphamide, both polysaccharide fractions restored T-cell and B-cell proportions in blood and spleen and eased gut and spleen tissue damage.

Results

Mouse cell proportions partly restored; no infection or survival outcome in the abstract.

Effect sizes as reported

Restored T and B cell proportions in drug-treated mice

Why this rating

One mouse study of purified lab fractions; not whole truffle and not people.

Form and dose studied

Lab-made polysaccharide fractions given to mice; not a food or supplement form we assessed.

Who was studied

Mice

Limits

Animal-only. Group sizes and doses were not in the abstract. No human data.

Why researchers looked

Mushroom polysaccharides are often studied for immune effects, so researchers tested truffle fractions in mice.

Traditional use

Not used for this in the sources read.

Proposed mechanism Animal research

Water- and alkali-extracted polysaccharide fractions changed gut bacteria (more Lactobacillus) and metabolite pathways in the mice (animal study).

A proposed mechanism does not show that the effect happens in people.

Never tested for safety in people as an extract.

4

As a food: nutrients

Not enough evidence

Measured by dry weight, Chinese truffle is mostly carbohydrate, then protein, with little fat. It is eaten in tiny amounts, so it adds little of any nutrient.

2 studiesEaten fresh in small amounts as a garnish.

Studies, doses and limits

What the trials found

Composition only. A 2025 review table lists for Tuber indicum from China about 52 to 80% carbohydrate, 13 to 23% protein and 2 to 7% fat (dry weight) and says the profile depends on species and region. Potassium, phosphorus and calcium are main minerals in truffles generally.

Results

Carbohydrate 52 to 80%, protein 13 to 23%, fat 2 to 7% (dry weight, quoted by the review from other papers)

Effect sizes as reported

Composition values only

Why this rating

Numbers are quoted from other papers by a review; no study measured what eating it does.

Form and dose studied

Eaten fresh in small amounts as a garnish.

Who was studied

Chinese black truffle

Limits

Dry-weight figures do not describe a real serving. Regional variation is large.

Why researchers looked

A review lists the make-up of truffles to describe their food value.

Traditional use

Described as a delicacy.

Proposed mechanism Laboratory research

Not a mechanism; this is composition.

A proposed mechanism does not show that the effect happens in people.

No safety problem found in the sources read.

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Antioxidant activity (test tube)

Very low certainty

In lab tests Chinese truffle extract mops up free radicals. One review ranked it second among three truffle species. These tests do not show a benefit from eating it.

1 studiesLab extracts; not eaten.

Studies, doses and limits

What the trials found

No human study. In the review's comparison, T. magnatum was highest, then T. indicum, then T. melanosporum. Lipid oxidation was inhibited by about 23% by T. indicum extract in one cited comparison.

Results

About 23% inhibition of lipid oxidation in one cited lab comparison

Effect sizes as reported

Lab assays only

Why this rating

Test-tube assays reported by a review; the original papers were not opened.

Form and dose studied

Lab extracts; not eaten.

Who was studied

Cells and chemical tests

Limits

Antioxidant assays rarely predict benefits in people.

Why researchers looked

Truffle phenolics and polysaccharides are often tested in antioxidant assays.

Traditional use

Not used for this in the sources read.

Proposed mechanism Laboratory research

Phenolic compounds and polysaccharides react with free radicals in lab assays; one polysaccharide protected a cell line (PC12) from hydrogen peroxide damage, as described by the review.

A proposed mechanism does not show that the effect happens in people.

No safety information.

2

Anti-inflammatory activity of one isolated compound

Very low certainty

One new compound purified from Chinese truffle lowered inflammation signals in mouse immune cells and in zebrafish. This is purified chemistry, not truffle as food.

1 studiesIsolated compound; not a food.

Studies, doses and limits

What the trials found

No human study. One of three new compounds had the effect in cells and zebrafish.

Results

Lower inflammatory mediators in LPS-stimulated mouse macrophages

Effect sizes as reported

One compound in cells and zebrafish

Why this rating

Cell and zebrafish findings for a purified compound.

Form and dose studied

Isolated compound; not a food.

Who was studied

Mouse macrophage cell line; zebrafish

Limits

Animals and cells only.

Why researchers looked

Researchers look for active compounds in a species used as food and medicine in China.

Traditional use

The paper calls T. indicum an edible fungus; no traditional medical use is stated in the abstract.

Proposed mechanism Laboratory research

Reduced nitric oxide, ROS, IL-6, TNF-alpha, COX-2 and iNOS in macrophages via the PI3K pathway (cell study).

A proposed mechanism does not show that the effect happens in people.

No safety information.

9

Any effect on human health

Not enough evidence

No clinical trial of Chinese truffle in people was found. A 2025 review says clinical trials of truffles in humans remain absent.

2 studiesn/a

Studies, doses and limits

What the trials found

No human outcome has been measured.

Effect sizes as reported

No human data

Why this rating

Absence of trials; the claims made for truffles rest on lab and animal work.

Limits

Nothing to assess.

Why researchers looked

Included so the page states plainly what is missing.

Proposed mechanism Laboratory research

n/a

A proposed mechanism does not show that the effect happens in people.

See the Safety tab.

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Connections to the rest of health

How Chinese Truffle connects to the rest of our health knowledge graph. Every link says what kind of connection it is. A safety link (for example to the liver) is a warning, not a benefit. A study that merely mentions a topic never creates a benefit link.

Explore every connection: goals, body systems, organs, symptoms, genes

B. Body systems

Connected toKind of connectionEvidence statusContextStudies
Immune system Preliminary mechanism Very low certainty Restored some immune-cell proportions in drug-treated mice; no human data.
Preparation or compound: Lab-made polysaccharide fractions
4
Immune System Biological association Very low certainty Studied for: Immune system (mouse study of extracted sugar chains) Studied for: Anti-inflammatory activity of one isolated compound 4 9

E. Health conditions

Connected toKind of connectionEvidence statusContextStudies
Mushroom allergy Adverse effect or risk Very low certainty Rare anaphylaxis to edible mushrooms is reported; no Chinese truffle case found.
Preparation or compound: Edible fungi (Chinese truffle data lacking)
1 16

K. Biological pathways

Connected toKind of connectionEvidence statusContextStudies
PI3K/Akt pathway Preliminary mechanism In vitro Lowered by one isolated compound in mouse macrophages. 9

L. Active compounds

Connected toKind of connectionEvidence statusContextStudies
Volatile aroma compounds (esters such as ethyl isobutyrate, 1-octen-3-ol, sulfur compounds) Biological association In vitro Give the truffle its smell; 95 were found across three grades.
Preparation or compound: Fruiting body
10
Polysaccharides (glucose-based sugar chains) Biological association Animal Changed immune-cell proportions and gut bacteria in mice.
Preparation or compound: Fruiting body
4
Sterols (ergosterol, brassicasterol and minor sterols) Biological association In vitro Pattern of minor sterols tells European from Chinese truffles.
Preparation or compound: Fruiting body
14
Phenolics Biological association In vitro Linked to lab antioxidant activity.
Preparation or compound: Fruiting body
2

Each connection is stored with the ingredient, the connected record, the kind of connection, the evidence status, the supporting studies, the preparation or compound involved, and a review date (last reviewed October 25, 2026).

Evidence at a glance: what the research found for 6 outcomes

1Low certainty
3Very low certainty
2Not enough evidence

Each outcome below is one thing researchers measured. Certainty is how far the evidence can be trusted, not how well it works. The full studies are on the next tab.

The evidence

The research centre for Chinese Truffle. Every record here was checked against PubMed or the publisher's page; we never list a study we have not verified.

Evidence by outcome

Bars show how many studies we found for each outcome, not how well it works. People are added up across trials only (reviews are not added, to avoid double counting).

How we rate evidence

High certainty

Several well-run trials or reviews agree; further research is unlikely to change the picture much.

Moderate certainty

Good trials point the same way, but some doubt remains.

Low certainty

Small, short or inconsistent trials. The finding could change with better research.

Very low certainty

Very little or very weak human data. Treat as a possibility only.

Mixed findings

Trials or reviews disagree with each other.

Not enough evidence

Not enough human research to say either way.

Evidence against

Good research found no benefit, or found harm.

We take the reviewers' own risk-of-bias and GRADE statements where they exist, and otherwise judge from study size, design, consistency, directness and whether a product matches what is sold. Many publications do not make evidence high. Method note: We read PubMed records and abstracts for 11 new papers (eight laboratory studies, one animal study and two taxonomy papers) and re-used five from the truffle page (two reviews, one oil study, two allergy papers). We read relevant passages of two full texts (an aroma paper and a 2025 review), and checked both Latin names in GBIF. Index Fungorum, EMA, FDA, EFSA, LiverTox and LactMed were not read. Only abstracts were read for most papers, so numbers come from abstracts. Certainty ratings are the compiler's own reading.

Study library: every study we checked 17
StudyDesignPeopleProduct, dose, lengthResult
Ali 2024
Agaricus bisporus mushroom anaphylaxis: A case report and review of the literature.
Journal of Allergy and Clinical Immunology: Global · PMID 39282616 · DOI
Case report
1
A 77-year-old woman with anaphylaxis after a button-mushroom omelette, plus 27 other cases from the literature
Agaricus bisporus (button, portobello) and other edible mushrooms
fruiting body Not shown here
Reactions were positive to several boiled edible mushrooms. The review found 27 other cases (average age 28.8). Cross-sensitisation between edible mushrooms was clear but followed no consistent pattern. Mushroom allergens named in some cases included alpha-mannosidase, alpha-trehalose, mannitol and a ribosomal protein.
Mushroom anaphylaxis is uncommon but reported
Methods, limits and funding

Outcomes: Anaphylaxis after eating mushrooms

Limitations: About button mushrooms, not truffles. No truffle case was found. Whether truffles cross-react is not known.

Funding and conflicts: No funding; authors report no conflict.

Read: abstract

Baldelli 2025
Bioactive Compounds and Antioxidant Potential of Truffles: A Comprehensive Review.
Antioxidants (Basel) · PMID 41300498 · DOI
Narrative review
fungus
Review of truffle composition and bioactivity Truffle fruiting bodies and extracts
fruiting body Not shown here
Full text read (Europe PMC). Dry weight: carbohydrates 37 to 80%, protein 11 to 35%, fat 2 to 7%, fibre 4 to 13%. Its Table 1 gives T. aestivum carbohydrates 60 to 79%, protein 14 to 24%, fat 1 to 5%, and T. melanosporum carbohydrates 74 to 75%, protein 12 to 18%, fat 2 to 4%. Potassium, phosphorus and calcium are about 80 to 90% of the minerals. More than 200 volatile compounds across species, only about 30 to 60 aroma-active in one species. Says most studies are test-tube or preclinical, and 'clinical trials in humans remain absent'. For Tuber indicum (China) the review's Table 1 lists roughly 52 to 80% carbohydrate, 13 to 23% protein and 2 to 7% fat by dry weight, and says the profile of truffles depends on species and region. In one comparison it ranks T. magnatum highest in antioxidant activity, then T. indicum, then T. melanosporum. Re-read for this page 2026-10-25 (full text, Europe PMC).
No human trial found by the authors
Methods, limits and funding

Outcomes: Composition, aroma, antioxidant and anti-tumour work, storage

Limitations: Narrative review; table values are ranges across studies, not measurements made by the authors. Freezing and canning lowered antioxidant capacity of processed truffles in the work it cites.

Funding and conflicts: Authors declare no conflicts of interest.

Read: full text

Epping 2022
Marker Substances in the Aroma of Truffles.
Molecules · PMID 36014409 · DOI
Laboratory study
fungus
Aroma profiles of several truffle species by headspace GC-MS, with an experiment on 19 truffle dogs Truffle fruiting bodies, headspace analysis
fruiting body Not shown here
The abstract finds that truffle aroma is mainly dimethyl sulfide and dimethyl disulfide as far as dogs are concerned, with some uncertainty. In the full text, the authors write that the aroma intensity is lowest in Tuber indicum, that T. indicum is visually similar to T. melanosporum and is exported to Europe and often used to counterfeit it, and that for this the Asian truffle is coated with artificial truffle oil to imitate the aroma (the authors cite an earlier reference for that last point; we did not open it).
Aroma weakest in T. indicum among species tested; counterfeiting statement is the authors' (cited from another paper)
Methods, limits and funding

Outcomes: Marker substances in truffle aroma; dog response

Limitations: The counterfeiting and oil-coating statements are the authors' own background statements referring to another paper, not measurements. We read the relevant passages of the full text only.

Funding and conflicts: Not stated

Read: full text (relevant passages)

Ji 2026
Structural Characteristics and Gut Microbiota-Mediated Immunomodulatory Mechanisms of Water- and Alkali-Extracted Polysaccharides from Tuber indicum.
Nutrients · PMID 42451205 · DOI
Animal study
animal
Mice with immune suppression caused by the drug cyclophosphamide (CTX) Lab-made water-extracted (TIWP) and alkali-extracted (TIAP) polysaccharide fractions from T. indicum
polysaccharide fractions from the fruiting body Not shown here
Both polysaccharide fractions restored the proportions of CD3+ T cells and CD19+ B cells in blood and spleen and eased damage to spleen and colon tissue in the mice. They shifted gut bacteria in different ways (more Lactobacillus with both). The authors call this a theoretical basis for functional foods.
Mouse immune-cell proportions partly restored after drug-caused suppression; no human data
Methods, limits and funding

Outcomes: Blood and spleen T and B cell proportions, spleen and colon tissue damage, gut bacteria, metabolites

Limitations: Mouse study of purified polysaccharide fractions, not whole truffle and not people. Doses and group sizes were not in the abstract. Not shown to prevent infections.

Funding and conflicts: Not stated in the abstract

Read: abstract

Kappacher 2022
Portable vs. Benchtop NIR-Sensor Technology for Classification and Quality Evaluation of Black Truffle.
Molecules · PMID 35163862 · DOI
Laboratory study
fungus
126
126 truffles of four species (Tuber melanosporum, T. indicum, T. aestivum, T. uncinatum)
Whole truffles measured by four near-infrared (NIR) instruments, three of them pocket-sized
fruiting body Not shown here
The authors say T. melanosporum fruiting bodies look very like T. indicum, so there is a risk of fraud through imported Asian truffles. Near-infrared measurement separated the costly T. melanosporum from T. indicum with up to 100% accuracy and separated all four species with 100% success in their tests. It also told fresh from frozen/thawed truffle.
Up to 100% accuracy for T. melanosporum vs T. indicum
Methods, limits and funding

Outcomes: Species classification, fresh vs frozen, harvest date

Limitations: Lab method testing; one set of samples; the study does not measure how much fraud happens. Truffles cannot be told apart by eye for inexperienced buyers, the authors say.

Funding and conflicts: Not stated in the abstract

Read: abstract

Kinoshita 2018
Using mating-type loci to improve taxonomy of the Tuber indicum complex, and discovery of a new species, T. longispinosum.
PLoS ONE · PMID 29590201 · DOI
Laboratory study
fungus
52
52 specimens: Japan (29), China (10 T. himalayense and 8 T. indicum), Taiwan (5 T. formosanum)
Fruiting bodies compared by shape and DNA
fruiting body Not shown here
Black truffles that look like T. indicum are a group of lookalike species (the T. indicum complex). DNA at five places showed three distinct lineages among the Japanese specimens. Japanese Tuber sp. 6 grouped with T. himalayense and T. formosanum, and the authors treat T. formosanum as a synonym of T. himalayense. A third group was named as a new species, T. longispinosum.
T. himalayense and T. indicum are separate names in this study; a complex with several lookalikes
Methods, limits and funding

Outcomes: Taxonomy of the T. indicum complex

Limitations: Taxonomy paper. It does not say what traders call the truffles they sell.

Funding and conflicts: Public research support; not stated in the abstract

Read: abstract

Kitade 2026
Sustained ascoma production and reproductive dynamics of the Asian black truffle Tuber himalayense in Japan.
Mycologia · PMID 42423500 · DOI
Laboratory study
fungus
Quercus serrata seedlings inoculated with T. himalayense spores in a nursery in Japan Spore-inoculated seedlings
fruiting body Not shown here
The authors call T. himalayense the Asian black truffle and say it is harvested commercially from natural habitats, but its populations have declined since the 1990s from habitat loss and overharvesting. After 7.5 years two truffles appeared, then 12 more. The authors call it the first successful cultivation of T. himalayense in Japan.
Cultivation success in a nursery; wild populations declining
Methods, limits and funding

Outcomes: First cultivation of T. himalayense in Japan

Limitations: Growing study; no food or health data.

Funding and conflicts: Not stated in the abstract

Read: abstract

Lee 2020
Potentials of truffles in nutritional and medicinal applications: a review.
Fungal Biology and Biotechnology · PMID 32566240 · DOI
Narrative review
fungus
Review of laboratory, animal and compositional work on truffles (Tuber and desert truffles) Truffle fruiting bodies and extracts
fruiting body Not shown here
Reviews phenolics, terpenoids, polysaccharides, anandamide, fatty acids and ergosterols and lab antitumour, antioxidant, antibacterial, anti-inflammatory and liver-protection findings. Full text read (Europe PMC): says more than 200 volatile compounds have been found; says truffle-flavoured oils contain more than 60 volatiles, 2,4-dithiapentane the most common; says truffles are highly perishable; its conclusion mentions 'no known side effects'.
No human trial summarised; lab and animal findings only
Methods, limits and funding

Outcomes: Composition, aroma, lab and animal bioactivity, preservation

Limitations: Narrative review, not systematic. Mixes Tuber and desert truffles (Terfezia, Tirmania), which are different fungi. 'No known side effects' is the authors' statement, not a safety study.

Funding and conflicts: Authors declare no conflict of interest; one author affiliation is a company laboratory (Plamica Labs).

Read: full text

Li 2024
Chemical constitutes from Tuber indicum with immunosuppressive activity uncovered by transcriptome analysis.
Fitoterapia · PMID 38097020 · DOI
Laboratory study
cell
Three new compounds isolated from T. indicum, tested in mouse macrophage cells and zebrafish Isolated compounds (a polyketide and two lactams) from T. indicum
isolated compound Not shown here
One of the three new compounds (compound 2) lowered nitric oxide, reactive oxygen species, IL-6, TNF-alpha, COX-2 and iNOS in the cells and acted on the PI3K pathway. A zebrafish model confirmed an anti-inflammatory effect. The paper labels this activity immunosuppressive (it dampens inflammation).
Cell and zebrafish findings for one isolated compound
Methods, limits and funding

Outcomes: Inflammatory mediators in LPS-stimulated RAW264.7 macrophages; zebrafish model

Limitations: Single purified compound from a chemical extraction, not truffle as eaten. Cells and zebrafish only.

Funding and conflicts: Not stated in the abstract

Read: abstract

Luo 2025
Insights into VOCs variation derived from Chinese black truffles (Tuber indicum) between grades via E-nose, HS-SPME-GC-MS, and HS-GC-IMS.
Food Chemistry: X · PMID 41278086 · DOI
Laboratory study
fungus
Chinese black truffles (T. indicum) of three commercial grades (G1, G2, G3) Fresh fruiting bodies, aroma analysis
fruiting body Not shown here
95 volatile compounds were found. The top grade (G1) had the most variety (75 compounds) and unique markers such as 2-butanone, and the strongest aroma intensity driven by esters (ethyl isobutyrate) and alcohols (1-octen-3-ol). Higher grades had sulfur compounds that lower grades lacked. The authors say this gives a chemical basis for grading beyond size and look.
Aroma richness differed by commercial grade
Methods, limits and funding

Outcomes: Volatile organic compounds, odour activity values by grade

Limitations: Chemistry of one species, three grades; sample numbers not in the abstract. It describes smell, not a health effect.

Funding and conflicts: Not stated in the abstract

Read: abstract

Mix 2023
From Nontargeted to Targeted Analysis: Feature Selection in the Differentiation of Truffle Species (Tuber spp.) Using 1H NMR Spectroscopy and Support Vector Machine.
Journal of Agricultural and Food Chemistry · PMID 37934755 · DOI
Laboratory study
fungus
80
80 truffle samples of five species (T. aestivum, T. borchii, T. indicum, T. magnatum, T. melanosporum)
Polar extracts analysed by NMR
fruiting body Not shown here
The authors say non-professionals can hardly tell truffle species apart by sight, which makes food fraud easy. The black look-alikes T. melanosporum and T. indicum were classified 100% correctly, and a model could tell all five species apart. Betaine and ribonate were proposed as markers for two of the species (T. borchii and T. melanosporum).
T. melanosporum vs T. indicum classified 100% correctly
Methods, limits and funding

Outcomes: Species discrimination

Limitations: Lab method on 80 samples; not a market survey.

Funding and conflicts: Not stated in the abstract

Read: abstract

Pacioni 2014
Composition of commercial truffle flavored oils with GC-MS analysis and discrimination with an electronic nose.
Food Chemistry · PMID 24176309 · DOI
Laboratory study
n/a
18
18 olive oil samples flavoured with white or black truffle, bought in Italy
Commercial truffle-flavoured olive oils
Not shown here
63 volatile compounds detected: 32 attributed to olive oil, 19 to truffles, and 12 foreign compounds of dubious origin (synthesis and/or breakdown). The authors say the finding confirms the established malpractice of using bis(methylthio)methane in black-truffle flavourings.
19 of 63 volatiles attributed to truffle; 12 foreign
Methods, limits and funding

Outcomes: Volatile compounds by GC-MS; electronic nose

Limitations: Only 18 Italian samples; not a survey of all oils on sale. Bis(methylthio)methane (also called 2,4-dithiapentane) also occurs naturally in white truffle, so its presence alone does not prove a synthetic source.

Funding and conflicts: Research support from non-US government sources per the record.

Read: abstract

Qiao 2018
Phylogeography and population genetic analyses reveal the speciation of the Tuber indicum complex.
Fungal Genetics and Biology · PMID 29448031 · DOI
Laboratory study
fungus
31 wild populations of the T. indicum complex in southwest China DNA markers (ITS, SSR)
fruiting body Not shown here
Two distinct lineages, called Tuber cf. indicum and Tuber cf. himalayense, were found within the T. indicum complex in southwest China, with different geographic patterns along river systems. The authors say the findings matter for protecting truffle diversity in the region.
Two lineages in southwest China
Methods, limits and funding

Outcomes: Population structure

Limitations: Genetic study of wild populations; says nothing on food quality or health.

Funding and conflicts: Not stated in the abstract

Read: abstract

Sommer 2020
Differentiation of European and Chinese Truffle (Tuber sp.) Species by Means of Sterol Fingerprints.
Journal of Agricultural and Food Chemistry · PMID 33138362 · DOI
Laboratory study
fungus
Five Tuber species including T. indicum varieties Truffle sterol patterns
fruiting body Not shown here
Sterol patterns differed in a characteristic way between five species (T. magnatum, T. melanosporum, T. aestivum, T. albidum and T. indicum varieties) whatever the country of origin. 27 sterols were measured and eight minor sterols were proposed as markers to tell European from Chinese truffles. The authors frame this as a way to prevent food fraud with valueless Tuber species.
Sterol fingerprints separate European and Chinese truffles
Methods, limits and funding

Outcomes: Species differentiation

Limitations: Lab method; sample numbers not in the abstract.

Funding and conflicts: Not stated in the abstract

Read: abstract

Sow 2026
Rapid detection of cultivated truffle fungi (Tuber) from truffles and ectomycorrhizal root tips using LAMP.
Applied and Environmental Microbiology · PMID 42663474 · DOI
Laboratory study
fungus
Truffle fruiting bodies and root tips; rapid DNA tests for four species DNA-based LAMP tests (T. melanosporum, T. borchii, T. aestivum, T. brumale)
fruiting body Not shown here
The authors say non-target species such as T. indicum and T. brumale often look like the target species (T. melanosporum) and can be accidentally included when tree seedlings are inoculated, causing a persistent problem for orchard growers. They built rapid tests for four other species; T. indicum itself was not one of the tests.
Rapid species-specific DNA tests for four truffles
Methods, limits and funding

Outcomes: Detection of target and contaminant truffle species

Limitations: The new tests do not target T. indicum. It shows that mix-ups also happen on the growing side, not only at the market.

Funding and conflicts: Not stated in the abstract

Read: abstract

Xing 2022
Recent Advances in the Allergic Cross-Reactivity between Fungi and Foods.
Journal of Immunology Research · PMID 36249419 · DOI
Narrative review
Review of allergy to fungi and fungus-related foods Edible mushrooms, mycoprotein, foods fermented by fungi
Not shown here
Edible mushrooms and fungus-related foods can cause fungus food allergy syndrome through cross-reaction with airborne fungi. Symptoms range from oral allergy syndrome to severe anaphylaxis.
Cross-reactions reported
Methods, limits and funding

Outcomes: Fungus food allergy

Limitations: Review; not truffle-specific.

Funding and conflicts: Authors declare no conflict of interest.

Read: abstract

n/a 2026
GBIF Backbone Taxonomy species match: Tuber indicum and Tuber himalayense (API checked 2026-10-25)
n/a · Source
Database record
n/a
n/a n/a
Tuber indicum Cooke & Massee, 1892 is ACCEPTED (key 5499365; Fungi, Ascomycota, family Tuberaceae). Tuber himalayense B.C.Zhang & Minter is ACCEPTED (key 5499367). GBIF lists them as two separate accepted species.
Methods, limits and funding

Outcomes: Tuber indicum Cooke & Massee, 1892 is ACCEPTED (key 5499365; Fungi, Ascomycota, family Tuberaceae). Tuber himalayense B.C.Zhang & Minter is ACCEPTED (key 5499367). GBIF lists them as two separate accepted species.

Limitations: A database record; names change as research updates. Index Fungorum was not opened.

Funding and conflicts: Independent public information source

Read: full text

What we do not know yet

  • No human study of Chinese truffle for any outcome.
  • No survey measures how often Chinese truffle is sold as European truffle.
  • Which Latin name sellers use (indicum or himalayense) was not found.
  • No allergy, pregnancy, heavy-metal or pesticide data for Tuber indicum was read.
  • EMA, FDA, EFSA, LiverTox and LactMed statements were not read; the oil-coating claim cites a paper we did not open.

How new research is added

New studies are found by a saved PubMed search and placed in a review queue. A person reads each one before it changes any evidence rating or safety wording. New publications never change ratings automatically.

Lab markers

What changed in blood or saliva tests during trials. A changed number is not the same as feeling or being healthier, and we give no "normal ranges".

Safety

What studies and official sources say about side effects, medicines and who should check first. Each point shows what kind of evidence it comes from.

Main points to know 4
  • Chinese truffle is often passed off as costly European black truffle. Papers say Tuber indicum looks very like the Perigord truffle (Tuber melanosporum) and that beginners cannot tell them apart by eye. The authors of one aroma paper write that the cheaper Asian truffle is exported to Europe and often used to counterfeit the costly one, and that it is coated with artificial truffle oil to imitate the smell. This is a labelling and money issue, not a poison risk. No survey of how often it happens was found, so we make no claim about how common it is. Several lab methods can tell the species apart, but a shopper cannot do this at home. Laboratory study 5 3 11 14
  • Truffle oil may be flavoured, not made from truffle. In 18 Italian truffle-flavoured olive oils, 19 of 63 volatile compounds were attributed to truffle and 12 were foreign compounds of dubious origin. The authors say this confirms the established use of bis(methylthio)methane in black-truffle flavourings. This tells you about truffle oil in general, not Chinese truffle in particular. See the truffle page for more. Laboratory study 12 8
  • Names are mixed up: indicum, himalayense and look-alikes. Chinese black truffles belong to a group of look-alike species called the Tuber indicum complex. Databases list Tuber indicum and Tuber himalayense as two separate accepted species, and DNA studies found separate lineages in southwest China. We did not find a source saying which name sellers use on the product, so 'Chinese truffle' on a label may not tell you the exact species. Laboratory study 17 6 13
  • No safety study exists. No poisoning, allergy case or drug interaction specific to Chinese truffle was found, but nobody has tested it for safety either. Mushroom allergy is rare but reported, including severe reactions with other edible mushrooms. No report found 2 1 16
Side effects 2
EffectHow oftenSeverity and recoveryEvidence
Allergic reaction to fungi (rare)
Evidence is from other edible mushrooms.
No Chinese truffle case found; in one review of button-mushroom anaphylaxis, 27 other cases were describedmild to severe
Not described
Case report 1 16
No other adverse effects reported in the sources read
Absence of reports is not proof of safety.
Not measured; no human safety trialunknown
unknown
Narrative review 2 8
Liver

No liver injury from Tuber truffles was reported in the sources read. LiverTox was not searched. 2

This is a safety connection. It is not evidence that Chinese Truffle supports liver health.

Medicines and supplements 2
WithWhy it mattersImportanceEvidenceWhat to do
Prescription medicines in general
prescription
No interaction with any medicine was found in the sources read.No report found Not enough evidence 2 8Eating truffle as a flavouring is not known to interact with medicines. Ask a doctor or pharmacist before trying an extract or supplement, which has no safety data.
Immune-suppressing medicines
theoretical
Mouse work on extracted polysaccharides changed immune-cell proportions, and one isolated compound lowered inflammation signals in cells.These are lab and animal findings only. They do not show that eating truffle changes anyone's immune system or medicines.Animal study Not enough evidence 4 9No action needed for ordinary food amounts. Ask a doctor first if you take immune medicines and plan to use a concentrated extract.
Who should check first 2
SituationAdviceEvidence
Known mushroom or mould allergyAsk an allergy doctor before eating truffles, because cross-reaction between fungi is reported and truffle-specific data are missing.Narrative review 16 1
Pregnancy, breastfeeding and young childrenNo safety data specific to Chinese truffle were found. Truffle in normal meal amounts is a food, but ask a doctor or midwife if unsure, and avoid extracts and supplements.No report found 2
Overdose, product quality and regulators

Summary. No poisoning from Tuber truffles was described in the sources read.

Animal. The mouse study gave extracted polysaccharide fractions; its abstract reports no safety findings, and safety was not its aim.

Human doses studied. No human feeding study found. This page gives no amounts.

High dose or long term signals. Not studied.

Overdose response. Not described. Seek medical help for any severe reaction after eating.

Genotoxicity. Not read.

Toxic or hazardous parts. Fungus fruiting body only. Wild look-alike fungi were not examined in the sources read. Wild fungi should only be eaten when an expert has identified them.

The quality problems found in papers are wrong species and fake flavour. No contaminant test for Chinese truffle was read.

Wrong species / mislabelling. Lab methods using near-infrared light, NMR and sterol patterns separated T. indicum from T. melanosporum in the authors' tests (up to 100% accuracy in two studies). On the growing side, T. indicum and T. brumale can slip into truffle orchards when seedlings are inoculated. 5 11 14 15

Added aroma. One aroma paper states that Asian truffle is coated with artificial truffle oil to imitate the aroma; the authors cite another paper for this and we did not open it. 3

Heavy metals, radioactivity, pesticides. No measurement for T. indicum was found in the sources read. 2

Spoilage. Truffles are highly perishable; freezing and drying change the aroma. 8 5

When to get medical help
  • Swelling of lips, tongue or throat, wheezing, faintness or widespread hives soon after eating: call emergency services.
  • Vomiting, severe belly pain or confusion after eating any wild fungus: seek urgent medical care and keep a sample if possible.
  • Itchy mouth or tummy upset that returns each time you eat truffle or other mushrooms: see a doctor.

If someone may be poisoned or in a crisis, contact a clinician or emergency service straight away. In the US, Poison Control is 1-800-222-1222.

General information only, not medical advice. Ask a clinician or pharmacist before use, especially with medicines, in pregnancy or with a health condition. See the Natural Remedy Safety guide.

Frequently asked questions

What is Chinese truffle?

Chinese truffle is the common name for black truffles from Asia, usually Tuber indicum. It is an underground fungus eaten in small amounts for its smell and sold at a lower price than the European Perigord truffle.

17 2

Is Tuber indicum the same as Tuber himalayense?

Not according to GBIF, which lists them as two separate accepted species. They belong to a group of look-alike black truffles, and DNA studies show several lineages. We did not find which name sellers use on labels.

17 6 13

Is Chinese truffle sold as Perigord truffle?

Papers say it looks very like the Perigord truffle and has been used to counterfeit it, sometimes with added artificial truffle aroma. We found no survey of how often this happens. Lab tests can tell them apart; shoppers cannot do it by eye.

5 3 11 14

How can I tell which truffle I am buying?

You cannot reliably tell by looking, according to the authors of the lab studies. Ask the seller for the species name and origin in writing, and treat a very low price for a black Perigord truffle with suspicion.

5 11

Does Chinese truffle taste as good?

One study found its aroma intensity lowest among the species it tested, and another describes its flesh as almost tasteless. Taste is partly personal, and top-grade Chinese truffles had a richer aroma mix than lower grades.

3 10

Is Chinese truffle safe to eat?

No poisoning or interaction was found in the sources we read, but there is no safety study. As a flavouring in normal meal amounts it is a food. Mushroom allergy is rare but reported. Ask a doctor or pharmacist about extracts.

2 1 16

Does Chinese truffle boost the immune system?

No human study exists. A mouse study of lab-made sugar chains found some immune-cell proportions restored in drug-treated mice, which does not show an effect from eating truffle.

4 2

Does it have antioxidants?

Extracts show antioxidant activity in test-tube assays, ranked second of three species in one comparison. Test-tube results do not show that eating truffle helps your health.

2

Is it safe in pregnancy or for children?

No safety data specific to Chinese truffle were found. Ask a doctor or midwife if unsure, and avoid extracts and supplements.

2

Is truffle oil made from Chinese truffle?

Not necessarily. Most truffle oil studied was flavoured with added aroma compounds rather than made from truffle, and one paper says Asian truffle is coated with artificial truffle oil. Check the label for how the flavour was made.

12 3

Is it the same as magic truffles?

No. Magic truffles are Psilocybe fungi sold for psilocybin. Chinese truffle is a Tuber fungus eaten as food.

17

Explore by health goal

Editorial transparency
Written by
AlternativeMed editorial team. Research compiled with AI assistance, then checked against PubMed records.
Medical review
None. This page has not been reviewed by a physician or pharmacist.
First published
2026-10-25
Last substantive update
2026-10-25
How we research
We read PubMed records and abstracts for 11 new papers (eight laboratory studies, one animal study and two taxonomy papers) and re-used five from the truffle page (two reviews, one oil study, two allergy papers). We read relevant passages of two full texts (an aroma paper and a 2025 review), and checked both Latin names in GBIF. Index Fungorum, EMA, FDA, EFSA, LiverTox and LactMed were not read. Only abstracts were read for most papers, so numbers come from abstracts. Certainty ratings are the compiler's own reading.
How we rate evidence
See "How we rate evidence" in the Evidence tab.
Independence
No product is promoted on this page. No affiliate links are shown. This page is information, not a recommendation to eat or buy truffles.
Sources 17

Each source was opened and checked. Where we read only the abstract, it says so. The small numbers in the text point here.

  1. Ali SB, Smith W. Agaricus bisporus mushroom anaphylaxis: A case report and review of the literature.. Journal of Allergy and Clinical Immunology: Global. 2024. PMID 39282616. DOI 10.1016/j.jacig.2024.100324. (abstract)
  2. Baldelli S, Aiello G, De Bruno A, et al. Bioactive Compounds and Antioxidant Potential of Truffles: A Comprehensive Review.. Antioxidants (Basel). 2025. PMID 41300498. DOI 10.3390/antiox14111341. (full text)
  3. Epping R, Bliesener L, Weiss T. Marker Substances in the Aroma of Truffles.. Molecules. 2022. PMID 36014409. DOI 10.3390/molecules27165169. (full text (relevant passages))
  4. Ji H, Li M, Mao D, et al. Structural Characteristics and Gut Microbiota-Mediated Immunomodulatory Mechanisms of Water- and Alkali-Extracted Polysaccharides from Tuber indicum.. Nutrients. 2026. PMID 42451205. DOI 10.3390/nu18132202. (abstract)
  5. Kappacher C, Trübenbacher B, Losso K, et al. Portable vs. Benchtop NIR-Sensor Technology for Classification and Quality Evaluation of Black Truffle.. Molecules. 2022. PMID 35163862. DOI 10.3390/molecules27030589. (abstract)
  6. Kinoshita A, Nara K, Sasaki H, et al. Using mating-type loci to improve taxonomy of the Tuber indicum complex, and discovery of a new species, T. longispinosum.. PLoS ONE. 2018. PMID 29590201. DOI 10.1371/journal.pone.0193745. (abstract)
  7. Kitade Y, Mizutani K, Kinoshita A, et al. Sustained ascoma production and reproductive dynamics of the Asian black truffle Tuber himalayense in Japan.. Mycologia. 2026. PMID 42423500. DOI 10.1080/00275514.2026.2681290. (abstract)
  8. Lee H, Nam K, Zahra Z, et al. Potentials of truffles in nutritional and medicinal applications: a review.. Fungal Biology and Biotechnology. 2020. PMID 32566240. DOI 10.1186/s40694-020-00097-x. (full text)
  9. Li SN, Li XA, Zhang Q, et al. Chemical constitutes from Tuber indicum with immunosuppressive activity uncovered by transcriptome analysis.. Fitoterapia. 2024. PMID 38097020. DOI 10.1016/j.fitote.2023.105773. (abstract)
  10. Luo Y, Ouyang L, Zhang S, et al. Insights into VOCs variation derived from Chinese black truffles (Tuber indicum) between grades via E-nose, HS-SPME-GC-MS, and HS-GC-IMS.. Food Chemistry: X. 2025. PMID 41278086. DOI 10.1016/j.fochx.2025.102981. (abstract)
  11. Mix T, Janneschütz J, Ludwig R, et al. From Nontargeted to Targeted Analysis: Feature Selection in the Differentiation of Truffle Species (Tuber spp.) Using 1H NMR Spectroscopy and Support Vector Machine.. Journal of Agricultural and Food Chemistry. 2023. PMID 37934755. DOI 10.1021/acs.jafc.3c05786. (abstract)
  12. Pacioni G, Cerretani L, Procida G, et al. Composition of commercial truffle flavored oils with GC-MS analysis and discrimination with an electronic nose.. Food Chemistry. 2014. PMID 24176309. DOI 10.1016/j.foodchem.2013.09.016. (abstract)
  13. Qiao P, Tian W, Liu P, et al. Phylogeography and population genetic analyses reveal the speciation of the Tuber indicum complex.. Fungal Genetics and Biology. 2018. PMID 29448031. DOI 10.1016/j.fgb.2018.02.001. (abstract)
  14. Sommer K, Krauß S, Vetter W. Differentiation of European and Chinese Truffle (Tuber sp.) Species by Means of Sterol Fingerprints.. Journal of Agricultural and Food Chemistry. 2020. PMID 33138362. DOI 10.1021/acs.jafc.0c06011. (abstract)
  15. Sow A, Cooper A, Meadows I, et al. Rapid detection of cultivated truffle fungi (Tuber) from truffles and ectomycorrhizal root tips using LAMP.. Applied and Environmental Microbiology. 2026. PMID 42663474. DOI 10.1128/aem.01559-26. (abstract)
  16. Xing H, Wang J, Sun Y, et al. Recent Advances in the Allergic Cross-Reactivity between Fungi and Foods.. Journal of Immunology Research. 2022. PMID 36249419. DOI 10.1155/2022/7583400. (abstract)
  17. n/a. GBIF Backbone Taxonomy species match: Tuber indicum and Tuber himalayense (API checked 2026-10-25). n/a. 2026. (full text)

Where to buy

Check the label first. Whatever you buy, look for these:

  • Fruiting body versus mycelium on grain: the label should say which
  • The extract type and the beta-glucan amount, if stated
  • A third-party testing mark
  • Interactions: ask a pharmacist if you take medicines or blood thinners

Talk to a pharmacist or doctor before you start any supplement, especially if you take medicines. See the Safety tab for interactions.

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Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.