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Broccoli: Nutrients, What Research Shows and Safety

Broccoli as food: USDA nutrients, what studies say on sulforaphane and cancer, raw versus cooked, vitamin K and warfarin, gas and thyroid questions.

Content last updated . This page has not been medically reviewed.

Close-up of broccoli: nutrients, what research shows and safety

Broccoli (Brassica oleracea var. italica) is a vegetable in the cabbage family (Brassicaceae). The green flower heads and the tender stalk are eaten, raw or cooked. People eat it for its vitamins, fiber and sulfur-containing plant compounds called glucosinolates. This page covers broccoli as a food and keeps it apart from supplements and from hype.

Read this first

  • Warfarin and vitamin K: broccoli is high in vitamin K, which affects how warfarin works. The usual advice is to keep amounts steady from week to week and to tell your care team before big changes, not to avoid it. [1][2]
  • Allergy: any food can cause an allergic reaction. For trouble breathing or swelling of the face or throat, call 911. See food allergy basics and emergency signs.
  • Gas and bloating: the NHS lists broccoli among foods that can cause gas. [3]
  • Evidence in one line: studies of people who eat more broccoli link it with a somewhat lower cancer risk, but these are observational studies and cannot prove cause. We found no trial showing that eating broccoli prevents cancer.

What is in it (USDA values)

USDA FoodData Central, raw broccoli, SR Legacy item 170379. [4] The serving is the USDA household portion of 1 cup chopped (91 g).

NutrientPer 100 gPer 1 cup chopped (91 g)% Daily Value per serving
Energy34 kcal31 kcalnot set
Fiber2.6 g2.4 g8%
Total sugars1.7 g1.5 gnot set
Vitamin C89.2 mg81 mg90%
Vitamin K101.6 µg92 µg77%
Folate (DFE)63 µg57 µg14%
Potassium316 mg288 mg6%
Vitamin B60.17 mg0.15 mg9%
Manganese0.21 mg0.19 mg8%
Calcium47 mg43 mg3%
Vitamin A (RAE)31 µg28 µg3%
Lutein + zeaxanthin1,403 µg1,277 µgnot set

% Daily Value uses the FDA 2016 Daily Values; values vary with variety, ripeness and storage. Serving columns are our arithmetic from the USDA per-100 g values.

Broccoli's main plant compounds are glucosinolates, sulfur-containing chemicals that give cruciferous vegetables their pungent smell and bitter taste. During chopping, chewing and digestion they break down into active compounds such as isothiocyanates, including sulforaphane. [5][6] Most evidence that these compounds fight cancer comes from cells and from rats and mice; the National Cancer Institute says human studies have shown mixed results. [5] Broccoli also contains carotenoids; USDA lists lutein plus zeaxanthin in the table above. [4]

What research says

Health goalWhat the sources foundStrength of evidenceWhat was studied
Cancer risk (any type)A 2024 meta-analysis found lower cancer risk with more broccoli: odds ratio 0.64 in 23 case-control studies and relative risk 0.89 in 12 cohort studies. The authors note bias is possible, and the benefit for specific cancer sites appeared only in case-control studies. [7]Promising but limited (association only)Observational studies of people who ate broccoli as food
Prostate, colorectal, lung and breast cancerNCI summarizes cohort studies as showing little or no association with prostate and colorectal cancer, varied results for lung cancer, and no association in a pooled breast cancer analysis, while some case-control studies found lower risk. [5]MixedObservational studies of cruciferous vegetables
Preventing cancer by eating it, in trialsProper evidence not found in the sources we read.Insufficient evidenceN/A
Heart disease and early deathA meta-analysis of 95 prospective studies found inverse associations for cruciferous vegetables with cardiovascular disease, total cancer and death from any cause. It examined vegetables as a group, not broccoli alone. [8]Promising but limited (association only)Cohort studies of vegetable intake
Sulforaphane levels in the bodyIn 18 healthy adults, sulforaphane from lightly cooked fresh broccoli soup was about tenfold higher than from commercial frozen broccoli soup, because blanching before freezing destroys the plant enzyme myrosinase. This measures absorption, not health outcomes. [9]Lab or marker measure onlySmall crossover trial, soups
Sulforaphane and cancer cellsNCI reports that indoles and isothiocyanates inhibited cancer development in several organs in rats and mice. [5]Lab or animal onlyCells and animals
Thyroid functionA 2024 systematic review of 123 studies (cells, animals, people) found the vast majority cast doubt on antithyroid effects of brassica vegetables in humans; eating them with adequate iodine poses no adverse effects on thyroid function. [10]No good evidence of harm from food amountsMixed designs, vegetables and extracts

People who eat more broccoli also differ from others in diet, income, exercise and smoking, so a link is not proof that broccoli is the cause. Observational findings cannot show that eating broccoli prevents cancer.

Eaten as food vs taken as a supplement or extract. The studies above looked at the vegetable. Sulforaphane or glucoraphanin capsules and powders are different products, and we did not read supplement trials, so we make no claims about them. See sulforaphane and glucosinolates in cruciferous vegetables and functional foods vs supplements vs medicine. Broccoli sprouts are a separate product with their own food-safety warning; see raw sprouts, raw milk and undercooked foods.

Raw or cooked? Raw broccoli still contains the enzyme myrosinase, which turns glucosinolates into isothiocyanates in the upper gut. When broccoli is cooked, myrosinase is inactivated and the glucosinolates are mostly broken down later in the colon by gut bacteria. [11] A lab study found that myrosinase activity fell by 80% after 3 minutes of stir-frying, and that letting chopped broccoli sit for 90 minutes before stir-frying gave 2.8 times more sulforaphane. [12] These are findings about chemistry, not a recommendation on how to cook it, and no source we read shows that raw or cooked broccoli gives better health results.

How much is a normal serving

  • USDA household portion: 1 cup chopped is 91 g; 1 spear (about 5 inches) is 31 g. [4]
  • Official figures: the NHS counts 80 g of fresh, canned or frozen vegetables as one portion of its 5 A DAY. [13] The World Health Organization says at least 400 g of fruits and vegetables a day for people older than 10. [14] These figures are information, not a prescription.
  • Fresh, frozen and canned: in a lab comparison of eight fruits and vegetables, including broccoli, vitamin content in frozen produce was comparable to fresh and sometimes higher. Riboflavin was higher in frozen broccoli. [15] Commercial freezing includes blanching, which lowers sulforaphane formation as noted above. See fresh, frozen and canned produce.

Safety, allergy and medicines

  • Warfarin and other vitamin K questions: NHS names broccoli among sources of vitamin K. [2] MedlinePlus says some foods that contain vitamin K can affect how warfarin works and advises eating consistent amounts of vitamin K foods week to week and not eating large amounts of leafy green vegetables; talk to your doctor before diet changes. [1] For other medicines we did not find a source describing interactions with broccoli as a food. See foods and medicine interactions.
  • Gas and bloating: the NHS says cabbage, broccoli, cauliflower and Brussels sprouts can make you pass gas, and that bloating is often caused by gas from some vegetables. [3][16] We did not find a trial of broccoli and gas, so the strength of this effect and who is affected is not established in the sources we read. For persistent bloating, ask a clinician; see foods for gut health and bloating.
  • Thyroid: a review found commercial broccoli contains less than 10 µmol of goitrin (a compound that can lower thyroid iodine uptake) per 100 g serving and can be considered of minimal risk; collards, Brussels sprouts and some Russian kale contain more. [17] The 2024 systematic review found no adverse effect on thyroid function from eating brassica vegetables, particularly with adequate iodine. [10] People with thyroid disease or on thyroid medicine should ask their clinician; sources we read give no amounts for them. See cruciferous vegetables.
  • Allergy: the sources we read did not give specific data on broccoli allergy, so we make no claim about how common it is. Treat any reaction like any food reaction; see when to seek medical help after a food reaction.
  • Kidneys and potassium: broccoli has 6% of the Daily Value for potassium per cup, so it is not a very high-potassium vegetable by this measure. [4] The sources we read did not give broccoli-specific advice for kidney disease; ask your kidney team.
  • Pregnancy: the sources we read gave no special caution for broccoli as food. Raw sprouts are a separate food-safety issue (see the sprouts page linked above).
  • Pesticide residues: Proper evidence not found; we could not read a USDA Pesticide Data Program or similar source for broccoli this session.

Choosing, storing and food safety

  • Choose produce that is not bruised or damaged. Pre-cut or packaged produce should be refrigerated or on ice when you buy it. [18]
  • Store perishable produce properly, wash it thoroughly under running water before eating, and cut away damaged or bruised areas. [18]
  • Soap, detergent or commercial produce wash is not recommended for washing produce. [18]
  • Keep raw produce and cutting boards separate from raw meat, poultry and seafood. [18]

Related pages

VegetableBrassica oleracea var. italica

Health connections for Broccoli

What research links to eating or drinking this food, and how strong the evidence is. Many studies are observational or use juice, powder, oil or extracts rather than the food as eaten; each card says which.

Vegetable intake and cancer risk

Preliminary or mixed

Observational studies link eating more broccoli with lower cancer risk (case-control OR 0.64, cohort RR 0.89), but the authors note possible bias. This is association, not proof.

Supplements: No trial showing that eating broccoli prevents cancer was found in the sources read.

Cruciferous vegetables and specific cancers

Preliminary or mixed

NCI summarizes cohort studies as showing little or no association with prostate and colorectal cancer, varied results for lung cancer, and no association in a pooled breast cancer analysis; some case-control studies found lower risk.

Supplements: Mixed human evidence.

Sulforaphane from raw versus cooked broccoli

Lab or animal research only

Sulforaphane forms when the plant enzyme myrosinase (or gut bacteria) breaks down glucoraphanin. Heat destroys myrosinase: stir-frying cut its activity by 80% in 3 minutes in a lab study, and commercial blanching and freezing cut sulforaphane absorption about tenfold in 18 people.

Supplements: Findings are about chemistry and absorption, not health outcomes.

Vitamin K, vitamin C and folate as a food source

Established role

One cup chopped raw broccoli gives about 77% of the Daily Value for vitamin K, 90% for vitamin C and 14% for folate (USDA, FDA 2016 Daily Values). NHS says vitamin K is needed for blood clotting.

Supplements: Not a supplement claim; intake from food only.

Heart disease and early death (vegetable intake)

Preliminary or mixed

A 95-study meta-analysis of prospective studies found inverse associations for cruciferous vegetables with cardiovascular disease, total cancer and all-cause mortality. It looked at vegetables as a group, not broccoli alone.

Supplements: Association, not proof of cause.

Thyroid function and goitrogens

Preliminary or mixed

A 2024 systematic review of 123 studies found the vast majority cast doubt on antithyroid effects of brassica vegetables in humans; eating them with adequate iodine poses no adverse effects. A review found commercial broccoli has under 10 micromol goitrin per 100 g, minimal risk. People with thyroid disease should ask their clinician.

Supplements: Not applicable; no harm shown at food amounts.

Preventing cancer by eating broccoli (trials)

Not enough evidence

Proper evidence not found in the sources read for trials of broccoli intake preventing cancer.

Supplements: No good evidence of benefit from trials.

Fresh versus frozen broccoli

Preliminary or mixed

In a lab comparison of eight fruits and vegetables including broccoli, vitamin content of frozen produce was comparable to fresh and sometimes higher; commercial blanching lowers sulforaphane formation.

Supplements: Applies to vitamins and a marker, not disease outcomes.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Body systems (1)
  • Digestive SystemDocumented risk

    The NHS lists broccoli among foods that can cause gas and bloating in some people.

Body parts (2)
  • Blood VesselsPreliminary or mixed

    Cruciferous vegetable intake was linked with lower cardiovascular disease risk in cohort studies; this is association only.

  • ThyroidPreliminary or mixed

    A 2024 systematic review found no adverse effect of brassica vegetables on thyroid function in humans with adequate iodine; people with thyroid disease should ask their clinician.

Functional actions (1)
  • Anti-InflammatoryLab or animal research only

    NCI reports anti-inflammatory effects of glucosinolate breakdown products in cells and animals; human studies show mixed results.

Root causes (1)
  • Broccoli is high in vitamin K, which affects how warfarin works; keep intake steady and tell the care team about big changes.

Conditions & symptoms (2)
  • FlatulenceDocumented risk

    NHS lists broccoli among foods that can make you pass gas.

  • NeoplasmsPreliminary or mixed

    Observational studies link more broccoli with lower cancer risk, but with possible bias; no trial shows prevention.

Documented risks and interactions (3)
  • Vitamin K and warfarin. Broccoli is rich in vitamin K, which affects how warfarin works. Advice is to keep amounts consistent week to week and talk to the prescriber before big diet changes.
  • Gas and bloating. NHS lists broccoli among foods that can make you pass gas and says some vegetables commonly cause bloating from gas. No trial specific to broccoli was found.
  • Produce washing and food safety. FDA advises washing produce under running water, cutting away damaged areas, and not using soap or produce wash.

Explore all 48 vegetables

Frequently asked questions

Does broccoli prevent cancer?

Observational studies link eating more broccoli with lower cancer risk (odds ratio 0.64 in case-control studies, relative risk 0.89 in cohort studies), but the authors warn about bias. We found no trial showing that eating broccoli prevents cancer. [7]

Is raw or cooked broccoli better?

No source we read shows better health results either way. Cooking inactivates the enzyme myrosinase, so less sulforaphane forms in the upper gut; gut bacteria can still break down the glucosinolates in the colon. [11][12]

Can I eat broccoli if I take warfarin?

Many people do. MedlinePlus advises consistent amounts of vitamin K foods from week to week and talking with your doctor before diet changes. [1]

Does broccoli cause gas?

The NHS lists broccoli among foods that can make you pass gas. [3] How much it affects you varies, and we did not find a trial.

Is broccoli bad for the thyroid?

A 2024 systematic review found no adverse effect on thyroid function from eating brassica vegetables, particularly with adequate iodine. [10] Ask your clinician if you have a thyroid condition.

References
  1. MedlinePlus. Warfarin: MedlinePlus Drug Information. Read 2026-10-23.
  2. NHS. Vitamin K. Read 2026-10-23.
  3. NHS. Farting (flatulence). Read 2026-10-23.
  4. US Department of Agriculture. FoodData Central: Broccoli, raw (SR Legacy, FDC ID 170379). April 2018 release. Read 2026-10-23.
  5. National Cancer Institute. Cruciferous Vegetables and Cancer Prevention. Read 2026-10-23.
  6. Approaches for enhancing the stability and formation of sulforaphane. Food Chem 2021. PMID 33601652. Abstract read 2026-10-23.
  7. Baladia E et al. Broccoli consumption and risk of cancer: an updated systematic review and meta-analysis of observational studies. Nutrients 2024. PMID 38892516. Abstract read 2026-10-23.
  8. Aune D et al. Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies. Int J Epidemiol 2017. PMID 28338764. Abstract read 2026-10-23.
  9. Isothiocyanate concentrations and interconversion of sulforaphane to erucin in human subjects after consumption of commercial frozen broccoli compared to fresh broccoli. Mol Nutr Food Res 2012. PMID 23109475. Abstract read 2026-10-23.
  10. Galanty A et al. Do Brassica vegetables affect thyroid function? A comprehensive systematic review. Int J Mol Sci 2024. PMID 38612798. Abstract read 2026-10-23.
  11. Bioavailability of glucosinolates and their breakdown products: impact of processing. Front Nutr 2016. PMID 27579302. Abstract read 2026-10-23.
  12. Hydrolysis before stir-frying increases the isothiocyanate content of broccoli. J Agric Food Chem 2018. PMID 29357241. Abstract read 2026-10-23.
  13. NHS. 5 A DAY: what counts. Last reviewed 9 June 2026.
  14. World Health Organization. Healthy diet fact sheet. 26 January 2026.
  15. Bouzari A et al. Vitamin retention in eight fruits and vegetables: a comparison of refrigerated and frozen storage. J Agric Food Chem 2015. PMID 25526594. Abstract read 2026-10-23.
  16. NHS. Bloating. Read 2026-10-23.
  17. Felker P et al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev 2016. PMID 26946249. Abstract read 2026-10-23.
  18. US Food and Drug Administration. Selecting and Serving Produce Safely. Read 2026-10-23.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.