Liver Support
Nutrients connected to Liver Support
A link means the body needs the nutrient for this, or that low intake is linked to it. It does not mean extra supplements help if your intake is already adequate; each link shows how strong the evidence is.
- N-acetylcysteineClinically supported
Acetylcysteine is a hospital antidote for paracetamol overdose, given by clinicians. Supplements are not a substitute, and evidence for liver benefit in healthy people was not found.
Choline is needed to export fat from the liver; this is a nutrient role, not evidence that supplements treat liver disease.
- Milk ThistlePreliminary or mixed
Milk thistle is traditionally used for the liver, but NIH says trial results in liver disease are conflicting or too limited for firm conclusions, and two NIH-funded trials (hepatitis C and fatty liver with inflammation) showed no benefit.
- Antrodia camphorataPreliminary or mixed
Liver-protection findings in animals and two small human trials with mixed results.
- AmlaLab or animal research only
Hepatoprotective effects are reported in laboratory and animal studies only.
- Black seedLab or animal research only
Lab and animal studies describe liver-protective effects. A few small human trials in fatty liver disease exist but are not enough to confirm benefit.
- SchisandraPreliminary or mixed
Used traditionally for liver conditions. Small human studies, some uncontrolled and some combined with other substances, suggest possible liver-function benefit; larger studies are needed.
- KutkiPreliminary or mixed
One small 1996 trial in acute viral hepatitis reported benefit; other human studies are small, mostly open-label formula studies. Most evidence is from animals, so it is not an established liver treatment.
- Paddy straw mushroomLab or animal research only
A polysaccharide extract eased chemically induced liver injury in mice and cells; not tested in people.
- KokumLab or animal research only
A water extract of the rind lowered liver enzymes in alcohol-treated rats. Not shown in people, and the related plant Garcinia cambogia carries liver-injury reports.
- Hemlock reishiLab or animal research only
Preparations lowered liver-damage markers in rats and mice. No human study; the nearest human evidence for Ganoderma and the liver is a safety signal for reishi.
- King tuber mushroomLab or animal research only
Rat studies of chemically induced liver damage.
- Milky mushroomLab or animal research only
Ethanol extract protected mouse liver in one chemical-injury model.
- Lumpy bracketLab or animal research only
A hot-water extract protected rat livers in a chemical-injury model. No human data.
- Milk Thistle TeaPreliminary or mixed
Traditional EU use to support liver function; extract trials mixed.
- Japanese GinsengLab or animal research only
Shown only in cells or animals; no human trial found. Findings in cells and animals often do not carry over to people.
- ZamanihaLab or animal research only
An extract protected mouse liver in a paracetamol overdose model; not shown in people.
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