natural remedies · Ingredient
1,7,8,10,11,12,13,14,15,17,-decahydro-decahydro-17-(2-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2h-cyclopenta［α］penanthrene-3(6h,9h,14h)-one
Formula: C21H30O4 · MW: 346.4670000000001 · Drug-likeness: 0.806
⚗️ Identity
Name
1,7,8,10,11,12,13,14,15,17,-decahydro-decahydro-17-(2-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2h-cyclopenta［α］penanthrene-3(6h,9h,14h)-one
Aliases / Synonyms
CORTICOSTERONE; 50-22-6; 17-Deoxycortisol; Reichstein's substance H; Kendall's compound B; Corticosteron; 11beta,21-Dihydroxyprogesterone; Reichstein's B; 11-Hydroxycorticoaldosterone; (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione
🧪 Chemistry
Molecular Weight
346.4670
LogP
2.6667
Drug-likeness
0.806
H-Bond Acceptors
4
H-Bond Donors
2
Rotatable Bonds
2
🔗 External References
0
Clinical Trials
0
Meta-Analyses
5
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 33265983
2-Phenylethylamine (PEA) Ameliorates Corticosterone-Induced Depression-Like Phenotype via the BDNF/TrkB/CREB Signaling Pathway
Int J Mol Sci · 2020
PMID 33363533
Corticosterone Enhances the AMPK-Mediated Immunosuppressive Phenotype of Testicular Macrophages During Uropathogenic Escherichia coli Induced Orchitis
Front Immunol · 2020
PMID 33634460
Metformin Attenuates the Metabolic Disturbance and Depression-like Behaviors Induced by Corticosterone and Mediates the Glucose Metabolism Pathway
Pharmacopsychiatry · 2021
PMID 33790465
Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
Nature · 2021
PMID 34023293
Hippocampal mitogen-activated protein kinase phosphatase-1 regulates behavioral and systemic effects of chronic corticosterone administration
Biochem Pharmacol · 2021