natural remedies · Ingredient
17-beta-estradiol
Formula: C18H24O2 · MW: 272.388 · Drug-likeness: 0.757
⚗️ Identity
Name
17-beta-estradiol
Aliases / Synonyms
estradiol; beta-Estradiol; 17beta-Estradiol; 50-28-2; Oestradiol; Dihydrofolliculin; Estrace; Vivelle; progynon; Diogynets
🧪 Chemistry
Molecular Weight
272.3880
LogP
3.6092
Drug-likeness
0.757
Oral Bioavailability
12.4120
H-Bond Acceptors
2
H-Bond Donors
2
🔗 External References
HERB DB
PubChem CID
CAS Number
DrugBank
InChIKey
VOXZDWNPVJITMN-ZBRFXRBCSA-N
15
Clinical Trials
9
Meta-Analyses
0
PubMed References
Top Conditions Studied with 17-beta-estradiol
Postmenopausal Vaginal Atrophy 1
Climacteric Syndrome|Menopause|Hypoestrogenism 1
Soy protein is a recommended protein source in dietary guide 1
Overweight 1
Bioequivalence 1
School bullying behavior or peer victimization 1
Overactive Bladder Syndrome 1
Pain includes experimental pain and clinical pain conditions 1
Osteoporosis Risk|Menopause 1
Oral contraceptives are used by many women around the world. 1
Metastatic Breast Cancer 1
Molecular and genetic expression in endometrial samples or c 1
📋 Sample Trials
NCT05197374
Effect of Estradiol Pretreatment on Antagonist ICSI Cycles
Completed · Phase 4 · Female Infertility
NCT05586711
Local DHEA and Estradiol on Dyspareunia in Postmenopausal Women
Recruiting · Phase 4 · Vulvovaginal Atrophy|Genitourinary Syndr
NCT05243823
Vaginal Estradiol Tablets (Vagifem®) and Endometrial Cancer Risk in the Treatment of Postmenopausal Vaginal Atrophy
Completed · Postmenopausal Vaginal Atrophy
NCT05332106
Bioavailability of Estradiol Valerate and Dienogest 2 mg/2 mg With Regards to Reference Product
Completed · Phase 1 · Bioequivalence
NCT05221021
Vaginal Estradiol vs Oral Beta-3 Agonist for Overactive Bladder Syndrome
Recruiting · Phase 4 · Overactive Bladder Syndrome
NCT05617820
Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspareunia in Women With Vulvur and Vaginal Atrophy
Completed · Phase 3 · Dyspareunia
📊 Sample Meta-Analyses
CRD42020187219
The effect of using of estradiol, progestogen, or contraceptive pill as pretreatment for GnRH antagonist cycles
We would like to the study the effect of using of estradiol, progestogen, or con
CRD42020204087
The efficacy of luteal estradiol pretreatment prior to the GnRH antagonist protocol in normal responders, a systemic review and meta-analysis.
GnRH antagonist protocol had gaining popularity recently, however, its numbers o
CRD42022368235
Serum estradiol and cardiovascular events in postmenopausal individuals: a systematic review and meta-analysis
Cardiovascular-related mortality, adverse cardiovascular events (i.e., myocardia
CRD42023429752
Molecular and genetic regulation of the healthy endometrium by estrogens and progesterone: A systematic review
Molecular and genetic expression in endometrial samples or cell cultures from he
CRD42023439239
The effect of soy isoflavones on estrogen-related intermediate outcomes: A systematic review and meta-analysis of randomized controlled trials.
Soy protein is a recommended protein source in dietary guidelines and major card
CRD42023460827
Hormonal contraception and bone metabolism
Oral contraceptives are used by many women around the world. Combined oral contr
📚 Sample References
None linked yet.
🏥 Linked Health Topics 5 · matched via study conditions