natural remedies · Ingredient
(1s,4as,6r,8s,8as)-6-hydroxy-8-methyl-1-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-1,4a,5,6,8,8a-hexahydropyrano[4,3-d]pyran-4-carboxylic acid methyl ester
Formula: C17H26O11 · MW: 406.3840000000002 · Drug-likeness: 0.315
⚗️ Identity
Name
(1s,4as,6r,8s,8as)-6-hydroxy-8-methyl-1-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-1,4a,5,6,8,8a-hexahydropyrano[4,3-d]pyran-4-carboxylic acid methyl ester
Aliases / Synonyms
Morroniside; 25406-64-8; CHEBI:80852; (7Beta-Hydroxy)-Morroniside; methyl (1S,3R,4aS,8S,8aS)-3-hydroxy-1-methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,4a,8,8a-hexahydropyrano[3,4-c]pyran-5-carboxylate; Methyl (1S,3R,4aS,8S,8aS)-3-hydroxy-1-methyl-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,4a,8,8a-tetrahydro-1H,3H-pyrano[3,4-c]pyran-5-carboxylate; CHEMBL1209803; DTXSID60948257; HY-N0532; BDBM5027...
🧪 Chemistry
Molecular Weight
406.3840
LogP
-2.4243
Drug-likeness
0.315
Oral Bioavailability
13.8640
H-Bond Acceptors
11
H-Bond Donors
5
Rotatable Bonds
4
🔗 External References
0
Clinical Trials
0
Meta-Analyses
5
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32643284
Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis
Cell Prolif · 2020
PMID 33071778
Morroniside Inhibits H2O2-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro
Front Pharmacol · 2020
PMID 33804203
Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model
Int J Mol Sci · 2021
PMID 34638983
Anti-Osteoporotic Effect of Morroniside on Osteoblast and Osteoclast Differentiation In Vitro and Ovariectomized Mice In Vivo
Int J Mol Sci · 2021
PMID 34867417
Microglial M2 Polarization Mediated the Neuroprotective Effect of Morroniside in Transient MCAO-Induced Mice
Front Pharmacol · 2021