natural remedies · Ingredient
Coptisine
Formula: C19H14NO4+ · MW: 320.324 · Drug-likeness: 0.597
⚗️ Identity
Name
Coptisine
Aliases / Synonyms
3486-66-6; Coptisin; Coptisine sulfate; UNII-0GCL71VN14; 1198398-71-8; 0GCL71VN14; bis[methylenedioxy]protoberberine; CHEBI:67862; YHL II
🧪 Chemistry
Molecular Weight
320.3240
LogP
2.8078
Drug-likeness
0.597
Oral Bioavailability
30.6720
H-Bond Acceptors
4
🔗 External References
0
Clinical Trials
0
Meta-Analyses
2
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31336157
Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1
Pharmacol Res · 2019
PMID 32752099
Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway
Int J Mol Sci · 2020