natural remedies · Ingredient
Demethoxycurcumin
Formula: C20H18O5 · MW: 338.359 · Drug-likeness: 0.597
⚗️ Identity
Name
Demethoxycurcumin
Aliases / Synonyms
22608-11-3; 24939-17-1; curcumin II; monodemethoxycurcumin; desmethoxycurcumin; BHCFM; Demethoxy Curcumin; 4-Hydroxycinnamoyl(feroyl)methane; 33171-16-3
🧪 Chemistry
Molecular Weight
338.3590
LogP
3.3613
Drug-likeness
0.597
H-Bond Acceptors
5
H-Bond Donors
2
Rotatable Bonds
7
🔗 External References
HERB DB
PubChem CID
CAS Number
InChIKey
HJTVQHVGMGKONQ-LUZURFALSA-N
0
Clinical Trials
0
Meta-Analyses
3
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32188144
Dual Targeting of the p38 MAPK-HO-1 Axis and cIAP1/XIAP by Demethoxycurcumin Triggers Caspase-Mediated Apoptotic Cell Death in Oral Squamous Cell Carcinoma Cells
Cancers (Basel) · 2020
PMID 33582110
Dimethoxycurcumin reduces proliferation and induces apoptosis in renal tumor cells more efficiently than demethoxycurcumin and curcumin
Chem Biol Interact · 2021
PMID 35729841
Demethoxycurcumin mitigates inflammatory responses in lumbar disc herniation via MAPK and NF-κB pathways in vivo and in vitro
Int Immunopharmacol · 2022