natural remedies · Ingredient
Isorhamnetin
Formula: C16H12O7 · MW: 316.2649999999999 · Drug-likeness: 0.572
⚗️ Identity
Name
Isorhamnetin
Aliases / Synonyms
480-19-3; 3-Methylquercetin; Isorhamnetol; Quercetin 3'-methyl ether; 3'-Methoxyquercetin; 3'-O-Methylquercetin; isorhamnetine; iso-rhamnetin; 3'-Methoxy-3,4',5,7-tetrahydroxyflavone
🧪 Chemistry
Molecular Weight
316.2650
LogP
2.2910
Drug-likeness
0.572
Oral Bioavailability
49.6040
H-Bond Acceptors
7
H-Bond Donors
4
Rotatable Bonds
2
🔗 External References
0
Clinical Trials
0
Meta-Analyses
7
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31590241
Isorhamnetin Induces Cell Cycle Arrest and Apoptosis Via Reactive Oxygen Species-Mediated AMP-Activated Protein Kinase Signaling Pathway Activation in Human Bladder Cancer Cells
Cancers (Basel) · 2019
PMID 23824743
Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin
Cancer Res · 2013
PMID 32452118
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies
Phytother Res · 2020
PMID 33569004
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway
Front Pharmacol · 2021
PMID 35401244
Isorhamnetin Alleviates Airway Inflammation by Regulating the Nrf2/Keap1 Pathway in a Mouse Model of COPD
Front Pharmacol · 2022
PMID 36160711
Isorhamnetin Attenuated the Release of Interleukin-6 from β-Amyloid-Activated Microglia and Mitigated Interleukin-6-Mediated Neurotoxicity
Oxid Med Cell Longev · 2022