natural remedies · Ingredient
L-homocysteine
Formula: C4H9NO2S · MW: 135.188 · Drug-likeness: 0.466
⚗️ Identity
Name
L-homocysteine
Aliases / Synonyms
homocysteine; 6027-13-0; (2S)-2-amino-4-sulfanylbutanoic acid; (s)-2-amino-4-mercaptobutanoic acid; 2-AMINO-4-MERCAPTO-BUTYRIC ACID; CHEBI:17588; L-2-Amino-4-mercaptobutyric acid; (S)-2-Amino-4-mercaptobutyric acid; MFCD00151320
🧪 Chemistry
Molecular Weight
135.1880
LogP
-0.2818
Drug-likeness
0.466
H-Bond Acceptors
3
H-Bond Donors
3
Rotatable Bonds
3
🔗 External References
0
Clinical Trials
0
Meta-Analyses
7
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31733201
Homocysteine accelerates atherosclerosis by inhibiting scavenger receptor class B member1 via DNMT3b/SP1 pathway
J Mol Cell Cardiol · 2020
PMID 32150828
Homocysteine Disrupts Balance between MMP-9 and Its Tissue Inhibitor in Diabetic Retinopathy: The Role of DNA Methylation
Int J Mol Sci · 2020
PMID 32896601
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4
Free Radic Biol Med · 2020
PMID 33510642
Homocysteine Impairs Endothelial Cell Barrier Function and Angiogenic Potential via the Progranulin/EphA2 Pathway
Front Pharmacol · 2021
PMID 34057794
Homocysteine induces podocyte apoptosis by regulating miR-1929-5p expression through c-Myc, DNMT1 and EZH2
Mol Oncol · 2021
PMID 34478920
The regulation of Ero1-alpha in homocysteine-induced macrophage apoptosis and vulnerable plaque formation in atherosclerosis
Atherosclerosis · 2021