natural remedies · Ingredient
Vitamin b
Formula: C6H6N2O · MW: 122.127 · Drug-likeness: 0.577
⚗️ Identity
Name
Vitamin b
Aliases / Synonyms
nicotinamide; niacinamide; 98-92-0; 3-Pyridinecarboxamide; pyridine-3-carboxamide; Nicotinic acid amide; vitamin PP; Aminicotin; Amixicotyn; Papulex
🧪 Chemistry
Molecular Weight
122.1270
LogP
0.1805
Drug-likeness
0.577
H-Bond Acceptors
2
H-Bond Donors
1
Rotatable Bonds
1
🔗 External References
64
Clinical Trials
11
Meta-Analyses
9
PubMed References
Top Conditions Studied with Vitamin b
Hypercholesterolemia 6
Dyslipidemia 5
Flushing 3
Intermittent Claudication|Peripheral Vascular Disease 2
Parkinson's Disease 2
Mitochondrial Myopathies 2
Peripheral Sensory Neuropathy of Different Etiologies 1
Coronary Heart Disease 1
Acute Low Back Pain 1
Head and neck squamous cell carcinoma (HNSCC) is the seventh 1
HIV 1
Pelvic Floor Disorders|Ureter; Kink 1
📋 Sample Trials
NCT00046267
Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients
Completed · HIV Infections|Hypercholesterolemia|Hype
NCT00062556
Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication
Completed · Phase 3 · Intermittent Claudication|Peripheral Vas
NCT00203476
A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction
Completed · Phase 4 · Hyperlipidemia|Hypercholesterolemia
NCT00246376
Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia
Completed · Cardiovascular Diseases|Heart Diseases|H
NCT00271817
To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)
Completed · Phase 3 · Hypercholesterolemia
NCT00286234
Niacin, N-3 Fatty Acids and Insulin Resistance
Completed · Phase 4 · Metabolic Syndrome|Hypertriglyceridemia
📊 Sample Meta-Analyses
CRD42021275439
A meta-analysis on the association of vitamin B, D, and E levels with the progression and risk of Alzheimer's disease
Alzheimer's Disease, neurodegenerative disease, vitamin deficiency, mitigating r
CRD42016045972
Vitamin B for treating diabetic peripheral neuropathy [Cochrane Protocol]
The Cochrane Neuromuscular Disease Group
CRD42019135162
A systematic review and meta-analysis of the efficacy of vitamin B in the management of diabetic peripheral neuropathy
The most common complication of diabetes is peripheral neuropathy. This can mani
CRD42019146727
Homocysteine, vitamin B6, B12 and folic acid in patients with dementia, and vitamin B treatment effects on cognitive performance
Dementia is one of the most devastating chronic diseases in the elderly. It belo
CRD42020189673
Impact of vitamin B 6, B 9 & B 12 supplementations on hyperhomocysteinemia in stroke: A meta-analysis on randomized controlled trials.
In this meta-analysis, stroke condition will be assessed. Stroke is defined as a
CRD42021235040
Vitamin B status and its impact in postmenopausal women
Vitamin B plays an important role in maintaining the functions of the nervous sy
📚 Sample References
PMID 31710686
Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide
Cardiovasc Res · 2020
PMID 32912104
Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages
Circ Res · 2020
PMID 33576879
Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways
Cell Tissue Res · 2021
PMID 33924461
The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism
Int J Mol Sci · 2021
PMID 34190232
Dietary niacin affects intestinal morphology and functions via modulating cell proliferation in weaned piglets
Food Funct · 2021
PMID 35320002
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease
Sci Transl Med · 2022
🏥 Linked Health Topics 12 · matched via study conditions
Cardiovascular Diseases
group
Coronary Heart Disease
syndrome
Flushing
phenotype
Hypercholesterolemia
syndrome
Hyperlipidemia
syndrome
Obesity
syndrome
Polycystic Ovary Syndrome
syndrome
Retinal Vein Occlusion
syndrome
Mitochondrial Myopathies
group
Dyslipidemias
group
Acute Low Back Pain
phenotype
Carotid Atherosclerosis
syndrome