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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Acetylcholine

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Acetylcholine

Acetylcholine vasoreactivity testing for vasomotor angina 1 Diabetes|Retinopathy|Vascular Pathology 1 The use of acetylcholine in Italy for medical purposes is li 1

📋 Sample Trials

NCT00259701

Microvascular Reactivity.

Completed

📊 Sample Meta-Analyses

CRD42022111145

Safety and Diagnostic Utility of Intracoronary Acetylcholine Vasoreactivity Testing

Acetylcholine vasoreactivity testing for vasomotor angina

CRD42021245939

Role of alpha7 nicotinic acetylcholine receptor subunit on modulation of energy homeostasis in peripheral tissues: a systematic review

CRD42021289721

Use of intracoronary acetylcholine in cardiac catheterization laboratories

The use of acetylcholine in Italy for medical purposes is limited to the treatme

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Acetylcholine

⚗️ Identity

Name

Acetylcholine

Aliases / Synonyms

Choline acetate; O-Acetylcholine; 51-84-3; (2-Acetoxyethyl)trimethylammonium; Acetyl choline ion; Acetylcholinum; Choline acetate (ester); Acetyl choline cation; 2-(Acetyloxy)-N,N,N-trimethylethanaminium

🧪 Chemistry

Molecular Weight

146.2100

LogP

0.2557

Drug-likeness

0.421

Oral Bioavailability

27.7990

H-Bond Acceptors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC(=O)OCC[N+](C)(C)C

Isomeric SMILES

CC(=O)OCC[N+](C)(C)C

InChIKey

OIPILFWXSMYKGL-UHFFFAOYSA-N

InChI

InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1

🔗 External References

HERB DB

HBIN014467 ↗

PubChem CID

187 ↗

CAS Number

51-84-3 ↗

NPASS

NPC1591

HIT

C0854

SymMap

692

TCMID

351

TCMSP

MOL007355

🔍 Raw view — every non-empty column on this row (33 fields)

name

Acetylcholine

common names

herb ingredient id

HBIN014467

canonical smiles

CC(=O)OCC[N+](C)(C)C

isomeric smiles

CC(=O)OCC[N+](C)(C)C

inchi

InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1

inchikey

OIPILFWXSMYKGL-UHFFFAOYSA-N

mol wt

146.2100

num h acceptors

num h donors

mol logp

0.2557

num rotatable bonds

drug likeness

0.421

ob score

27.7990

cas id

51-84-3

symmap mol id

692

tcmid ingredient id

351

tcmsp ingredient id

MOL007355

pubchem cid

187

npass id

NPC1591

hit id

C0854

📋 Clinical Trials

1 · subject of clinical study

NCT00259701 Microvascular Reactivity.

→ Diabetes|Retinopathy|Vascular Pathology

📊 Meta-Analyses

3 · systematic review

CRD42022111145 Safety and Diagnostic Utility of Intracoronary Acetylcholine Vasoreactivity Test

→ Acetylcholine vasoreactivity testing for vasomotor

CRD42021245939 Role of alpha7 nicotinic acetylcholine receptor subunit on modulation of energy

CRD42021289721 Use of intracoronary acetylcholine in cardiac catheterization laboratories

→ The use of acetylcholine in Italy for medical purp

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables