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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Ado

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Ado

Coronary Artery Disease 9 Supraventricular Tachycardia 3 Atrial Fibrillation 2 Myocardial Infarction 1 Tuberculous Meningitis is a serious infection of central ner 1 Acute Myocardial Infarction 1 Heart Defects, Congenital|Cardiac Surgical Procedures|Myocar 1 patients with peptic ulcers 1 Acute Coronary Syndrome|No-Reflow Phenomenon|Normotensive 1 Supra-ventricular Tachycardia 1 Headache, Migraine 1 Microbiological confirmation of tuberculous pleural effusion 1

📋 Sample Trials

NCT00298636

Dose-Response of Adenosine for Perioperative Pain

Completed · Phase 2

NCT00349921

Clonidine Versus Adenosine to Treat Neuropathic Pain

Completed · Phase 2

NCT00413712

Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Management of SVT

Completed · Phase 4

📊 Sample Meta-Analyses

CRD42021284472

Performance of adenosine deaminase in synovial fluid for the diagnosis of tuberculous arthritis: meta-analysis

Infectious arthritis caused by Mycobascterium tuberculosis

CRD42022336559

Diagnostic test accuracy of adenosine deaminase for tuberculous meningitis: A systematic review and meta-analysis:

Tuberculous Meningitis is a serious infection of central nervous system by the b

CRD42022339582

Adenosine as adjunctive therapy in patients with acute coronary syndrome: when less is more. Updated meta-analysis of 26 randomized controlled trials.

Acute coronary syndromes. Percutaneous coronary intervention.

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Ado

⚗️ Identity

Name

Ado

Aliases / Synonyms

adenosine; 58-61-7; Adenocard; Adenoscan; Adenine riboside; beta-D-Adenosine; Nucleocardyl; Adenosin; Sandesin; Boniton

🧪 Chemistry

Molecular Weight

267.2450

LogP

-1.9800

Drug-likeness

0.491

Oral Bioavailability

15.9820

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

Isomeric SMILES

C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

InChIKey

OIRDTQYFTABQOQ-KQYNXXCUSA-N

InChI

InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

🔗 External References

HERB DB

HBIN014727 ↗

PubChem CID

60961 ↗

CAS Number

30143-02-3 ↗

NPASS

NPC156461

TCMID

618

TCMSP

MOL001787

🔍 Raw view — every non-empty column on this row (31 fields)

name

Ado

common names

adenosine; 58-61-7; Adenocard; Adenoscan; Adenine riboside; beta-D-Adenosine; Nucleocardyl; Adenosin; Sandesin; Boniton

herb ingredient id

HBIN014727

canonical smiles

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

isomeric smiles

C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

inchi

InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

inchikey

OIRDTQYFTABQOQ-KQYNXXCUSA-N

mol wt

267.2450

num h acceptors

num h donors

mol logp

-1.9800

num rotatable bonds

drug likeness

0.491

ob score

15.9820

cas id

30143-02-3

tcmid ingredient id

618

tcmsp ingredient id

MOL001787

pubchem cid

60961

npass id

NPC156461

🏥 Linked Health Topics

10 · studied for these conditions (text bridge)

Myocardial Infarction

Supraventricular Tachycardia

syndrome

Acute Myocardial Infarction

syndrome

Paroxysmal Atrial Fibrillation

syndrome

Coronary Artery Disease

syndrome

📋 Clinical Trials

12 · subject of clinical study

NCT00298636 Dose-Response of Adenosine for Perioperative Pain

→ Perioperative Pain

NCT00349921 Clonidine Versus Adenosine to Treat Neuropathic Pain

→ Pain

NCT00413712 Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Managem

→ Supraventricular Tachycardia

NCT00590070 THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myo

→ Myocardial Infarction

NCT00712764 Role of Adenosine in the Control of Choroidal Blood Flow During Changes in Ocula

→ Ocular Physiology|Microcirculation

NCT00781404 Myocardial Protection With Adenosine During Primary Percutaneous Coronary Interv

→ Acute Myocardial Infarction

NCT00881686 Myocardial Protection With Adenosine Preconditioning

→ Heart Defects, Congenital|Cardiac Surgical Procedu

NCT01123525 Adenosine Cardioplegia; Improved Cardioprotection?

→ Angina Pectoris

NCT01148147 Intracoronary Adenosine Administration to Prevent Periprocedural Myonecrosis in

→ Coronary Angioplasty

NCT01161121 Comparison of Intravenous Adenosine Infusion With Regadenoson Bolus for Inducing

→ Coronary Artery Disease

NCT01370265 Myocardial Blood Flow by PET and N-13 Ammonia During Regadenoson vs Adenosine St

→ Coronary Artery Disease

NCT01495481 Dexmedetomidine and Adenosine: Therapeutic Use for SVT

→ Supraventricular Tachycardia

📊 Meta-Analyses

12 · systematic review

CRD42021284472 Performance of adenosine deaminase in synovial fluid for the diagnosis of tuberc

→ Infectious arthritis caused by Mycobascterium tube

CRD42022336559 Diagnostic test accuracy of adenosine deaminase for tuberculous meningitis: A sy

→ Tuberculous Meningitis is a serious infection of c

CRD42022339582 Adenosine as adjunctive therapy in patients with acute coronary syndrome: when l

→ Acute coronary syndromes. Percutaneous coronary in

CRD42022341909 Diagnostic test accuracy of ascitic fluid adenosine deaminase for tuberculous pe

→ Tuberculous peritonitis is the most common cause o

CRD42022345125 The single-syringe versus the double-syringe techniques of adenosine administrat

→ Given the physical logistic issues and inconvenien

CRD42022359917 Diagnostic accuracy of lactate dehydrogenase/adenosine deaminase ratio in differ

→ Microbiological confirmation of tuberculous pleura

CRD42022297931 The diagnostic accuracy of adenosine deaminase for abdominal tuberculosis: a sys

→ Abdominal tuberculosis is one of the most easily i

CRD42020222609 Comparative diagnostic accuracy of pleural fluid unstimulated interferon-gamma a

→ Tuberculous pleural effusion is one of the commone

CRD42020161820 Adenosine antagonists for prevention of acute kidney injury post neonatal perina

→ Asphyxia remains a common problem in the neonatal

CRD42020183591 Effects of adenosine levels on peptic ulcers: a systematic review and meta-analy

→ patients with peptic ulcers

CRD42023459517 Efficacy and safety of adenosine, rapid ventricular pacing and hypothermia in ce

→ According to the American Association of Neurosurg

CRD42023494116 Safety and Efficacy of Adenosine-assisted Embolization of Brain Arteriovenous Ma

→ Despite multiple studies, the safety and efficacy

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables