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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Aminoacetic acid

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Aminoacetic acid

Schizophrenia Prodrome 1 Covid19 1 Schizophrenia 1 COVID-19|SARS-CoV Infection|SARS (Severe Acute Respiratory S 1 Schizo-affective Disorder|Bipolar Disorder 1 The condition under investigation is peri-implantitis, which 1 Psychotic Disorder|Schizoaffecitve Disorder|Schizophrenia 1 Periodontal disease is an inflammatory and destructive disea 1 Pregnancy 1 Outcomes associated with populations in type 2 diabetes mell 1 Plaque, Dental 1 Latest studies mention that the use of glycine in TURP is re 1

📋 Sample Trials

NCT00005658

Glycine to Treat Psychotic Disorders in Children

Completed · Phase 2

NCT00291226

Glycine vs Placebo for the Schizophrenia Prodrome

Completed · Phase 2|Phase 3

NCT00405535

Adjunctive Glycine for Obsessive Compulsive Disorder

Completed

📊 Sample Meta-Analyses

CRD42016036743

Safety and clinical effects of dietary glycine supplementation in humans

Glycine is an amino acid that is critical in humans for healthy metabolism inclu

CRD42019128599

Is glycine air-polishing effective to reduce the effects of peri-implantitis? A systematic review and meta-analysis

The condition under investigation is peri-implantitis, which is a pathological c

CRD42022312730

Does glycine administration improve characteristics of physiological systems in adults?

Changes in the characteristics of the physiological systems resulting from glyci

📚 Sample References

PMID 32110933

Glycine Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Regulating NLRP3 Inflammasome and NRF2 Signaling

Nutrients · 2020

PMID 32209436

Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle

Mol Ther · 2020

PMID 33772775

Glycine suppresses kidney calcium oxalate crystal depositions via regulating urinary excretions of oxalate and citrate

J Cell Physiol · 2021

⚗️ All Ingredient data fields for Aminoacetic acid

⚗️ Identity

Name

Aminoacetic acid

Aliases / Synonyms

glycine; 56-40-6; 2-Aminoacetic acid; Glycocoll; Aminoethanoic acid; Glycolixir; H-Gly-OH; Glicoamin; Glycosthene

🧪 Chemistry

Molecular Weight

75.0670

LogP

-0.9703

Drug-likeness

0.421

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C(C(=O)O)N

Isomeric SMILES

C(C(=O)O)N

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

InChI

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

🔗 External References

HERB DB

HBIN015853 ↗

PubChem CID

750 ↗

DrugBank

DB00145 ↗

TCMID

33592

🔍 Raw view — every non-empty column on this row (28 fields)

name

Aminoacetic acid

common names

glycine; 56-40-6; 2-Aminoacetic acid; Glycocoll; Aminoethanoic acid; Glycolixir; H-Gly-OH; Glicoamin; Glycosthene

herb ingredient id

HBIN015853

canonical smiles

C(C(=O)O)N

isomeric smiles

C(C(=O)O)N

inchi

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

inchikey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

mol wt

75.0670

num h acceptors

num h donors

mol logp

-0.9703

num rotatable bonds

drug likeness

0.421

tcmid ingredient id

33592

pubchem cid

750

drugbank id

DB00145

🏥 Linked Health Topics

3 · studied for these conditions (text bridge)

Peri-Implant Mucositis

syndrome

📋 Clinical Trials

12 · subject of clinical study

NCT00005658 Glycine to Treat Psychotic Disorders in Children

→ Psychotic Disorder|Schizoaffecitve Disorder|Schizo

NCT00291226 Glycine vs Placebo for the Schizophrenia Prodrome

→ Schizophrenia Prodrome

NCT00405535 Adjunctive Glycine for Obsessive Compulsive Disorder

→ Obsessive Compulsive Disorder

NCT04658134 Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity

→ Morbid Obesity|Glycine; Metabolic Disorder

NCT00268749 Glycine Treatment of Prodromal Symptoms

→ Schizophrenia

NCT01610011 Acute Glycine Pharmacodynamic Study

→ Schizophrenia|Psychotic Disorders

NCT01720316 Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders

→ Schizo-affective Disorder|Bipolar Disorder

NCT02149953 Determination of Glycine Requirement in Pregnancy

→ Pregnancy

NCT02655276 Sublingual Glycine vs. Placebo on Attentional Difficulties and Hyperactivity in

→ Motor Activity|Attention Deficit|Stress, Psycholog

NCT03031756 Efficacy of Glycine Powder Air-Polishing Combined With Scaling and Root Planing

→ Halitosis

NCT04443673 Glycine Supplement for Severe COVID-19

→ COVID-19|SARS-CoV Infection|SARS (Severe Acute Res

NCT04703036 Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19

→ Covid19

📊 Meta-Analyses

7 · systematic review

CRD42016036743 Safety and clinical effects of dietary glycine supplementation in humans

→ Glycine is an amino acid that is critical in human

CRD42019128599 Is glycine air-polishing effective to reduce the effects of peri-implantitis? A

→ The condition under investigation is peri-implanti

CRD42022312730 Does glycine administration improve characteristics of physiological systems in

→ Changes in the characteristics of the physiologica

CRD42022361997 Effect of glycine on the incidence of transurethral resection syndrome : a syste

→ Latest studies mention that the use of glycine in

CRD42022366792 Comparative Clinical Effects of Erythritol，Glycine and Trehalose as Subgi

→ Periodontal disease is an inflammatory and destruc

CRD42023459005 Role of dietary supplements in type 2 diabetes mellitus with coronary heart dise

→ Outcomes associated with populations in type 2 dia

CRD42023485500 The role of the glutamatergic system on compulsive behavior: A systematic review

→ Body-focused repetitive behaviors, and other compu

📚 PubMed References

4 · cited research

PMID 32110933 Glycine Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Regulating NL

Nutrients

PMID 32209436 Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonu

Mol Ther

PMID 33772775 Glycine suppresses kidney calcium oxalate crystal depositions via regulating uri

J Cell Physiol

PMID 34535959 Gut barrier and microbiota changes with glycine and branched-chain amino acid su

J Cachexia Sarcopenia Muscle

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables