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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Ingredient
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Gene Target
15,505
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Disease
30,170
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
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🏥 Disease / Health Topic

Hypogonadism

Open on HERB 2.0 ↗
108
Clinical Trials
18
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT00080483
Testosterone and Growth Hormone for Bone Loss in Men
Completed · Phase 2
NCT00161486
The Effects of Testosterone on Prostate Tissue (ACYP-1)
Completed · Phase 1
NCT00193700
Pharmacokinetic Evaluation of Testosterone Gel (1%)
Completed · Phase 1
📊 Sample Meta-Analyses
CRD42014009963
Efficacy and safety of testosterone replacement therapy in adult men: a systematic review and network meta-analysis
Testosterone is indicated as a replacement therapy in adult men with diagnosed a
CRD42015015839
The effect of testosterone replacement therapy on erythropoiesis in middle aged and aged men: a systematic review protocol
Testosterone deficiency in men has become a common concern for men globally. Low
CRD42017055501
Testosterone therapy for high-risk prostate cancer survivors: a systematic review and meta-analysis
High-risk prostate cancer and testosterone deficiency, also known as late onset
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Hypogonadism
🏥 Names
Disease Name
Hypogonadism
Alias Names
Hypogonadism; Hypogonadism, Hypogonadotropic; Hypergonadotropic Hypogonadism; Hypogonadism, Isolated Hypogonadotropic; Decreased Activity of Gonads
Topic Type
syndrome
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Disease or Syndrome
MeSH Class
Endocrine System Diseases
HPO Class
Abnormality of the endocrine system; Abnormality of the genitourinary system
DO Class
disease of anatomical entity
🔗 External References
HERB DB
HBDIS001488 ↗
MeSH
D007006 ↗
HPO
HP:0000135 ↗
Disease Ontology
1924
DisGeNET
C0020619
🔍 Raw view — every non-empty column on this row (29 fields)
name
Hypogonadism
alias name
Hypogonadism; Hypogonadism, Hypogonadotropic; Hypergonadotropic Hypogonadism; Hypogonadism, Isolated Hypogonadotropic; Decreased Activity of Gonads
topic type
syndrome
disgenet disease type
disease
umls disease type
Disease or Syndrome
mesh disease class
Endocrine System Diseases
hpo disease class
Abnormality of the endocrine system; Abnormality of the genitourinary system
do disease class
disease of anatomical entity
umls disease type id
T047
mesh disease class id
C19
hpo disease class id
HP:0000119; HP:0000818
do disease class id
DOID:7
herb disease id
HBDIS001488
disgenet id
C0020619
mesh id
D007006
hpo id
HP:0000135
do id
1924

⚗️ Related Ingredients

3 · shared evidence
Enanthic acid
Femara
Testosterone

📋 Clinical Trials

12 · subject of clinical study
NCT00080483 Testosterone and Growth Hormone for Bone Loss in Men
→ Hypopituitarism|Hypogonadism|Growth Hormone Defici
NCT00161486 The Effects of Testosterone on Prostate Tissue (ACYP-1)
→ Hypogonadism|Contraception
NCT00193700 Pharmacokinetic Evaluation of Testosterone Gel (1%)
→ Primary or Secondary Hypogonadism|Constitutional D
NCT00202462 The Effect of Testosterone on Mood and Quality of Life
→ Gonadal Disorders|Depressive Disorder|Hypogonadism
NCT00244023 Co-Administering Testosterone With PDE5 Inhibitors in ED Patients Non Responders
→ Erectile Dysfunction|Hypogonadism
NCT00266864 Testosterone Replacement Therapy in Chronic Spinal Cord Injury
→ Spinal Cord Injury|Hypogonadism
NCT00345969 Exercise and Testosterone Therapy in Elderly Men With Physical Frailty
→ Physical Frailty|Hip Fracture|Elective Hip Replace
NCT00349362 Testosterone for Men With Insulin Treated Type 2 Diabetes
→ Hypogonadism|Diabetes
NCT00365794 Effects of Testosterone Gel on Carbohydrate and Lipid Metabolism In Elderly Obes
→ Aging|Obesity|Insulin Resistance|Hypogonadism
NCT00372008 Pharmacokinetics of Testosterone Lotion in the Treatment of Hypogonadal Males
→ Hypogonadism
NCT00398580 28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men
→ Hypogonadism|Hypogonadism, Male
NCT00400335 Study On Bioavailability And Pharmacokinetics Of Various Doses Of Testosterone A
→ Hypogonadism|Hypogonadism, Male

📊 Meta-Analyses

12 · systematic review
CRD42014009963 Efficacy and safety of testosterone replacement therapy in adult men: a systemat
→ Testosterone is indicated as a replacement therapy
CRD42015015839 The effect of testosterone replacement therapy on erythropoiesis in middle aged
→ Testosterone deficiency in men has become a common
CRD42017055501 Testosterone therapy for high-risk prostate cancer survivors: a systematic revie
→ High-risk prostate cancer and testosterone deficie
CRD42017077927 The effect of testosterone replacement therapy on endothelial health-related par
→ Late onset hypogonadism represents an important fi
CRD42018102399 Relationship of Vitamin D status with testosterone levels: a systematic review a
→ Hypovitaminosis D, male hypogonadism.
CRD42018102399 Relationship of Vitamin D status with testosterone levels: a systematic review a
→ Hypovitaminosis D, male hypogonadism.
CRD42020131461 Effects of exercise training on testosterone levels in men: a systematic review
→ Hypogonadism (testosterone concentration below 300
CRD42019137133 Should we combine exercise with an anabolic agent to get a better prognosis insk
→ Clinical situations: burned, HIV, chronic obstruct
CRD42020201024 Effect of testosterone replacement therapy to treat metabolic disturbances in la
→ age related late onset hypogonadism
CRD42020215680 The prevalence of polycythemia amongst different Testosterone replacement treatm
→ Male hypogonadism (HG) is defined as a clinical co
CRD42021240009 Efficacy and safety of Testosterone therapy in Type 2 Diabetic patients with hyp
→ This systematic review and meta-analysis assessed
CRD42021243806 Effects oftestosterone replacement therapy on glycolipid metabolism amonghypogon
→ Diabetesis a condition that has been increasing in
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables