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Disease
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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
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⚗️ Ingredient

Bakuchiol

Open on HERB 2.0 ↗
2
Clinical Trials
0
Meta-Analyses
3
PubMed References
Top Conditions Studied with Bakuchiol
Wrinkle|Photoaging 1 Acne Vulgaris 1
📋 Sample Trials
NCT03112863
Comparison of the Cosmetic Effects of Bakuchiol and Retinol
Completed · Early_Phase 1
NCT05069272
Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne
Recruiting
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32499702
Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP and the Phosphorylation of AMPK After Subarachnoid Hemorrhage in Mice
Front Pharmacol · 2020
PMID 33062139
Bakuchiol Alleviates Hyperglycemia-Induced Diabetic Cardiomyopathy by Reducing Myocardial Oxidative Stress via Activating the SIRT1/Nrf2 Signaling Pathway
Oxid Med Cell Longev · 2020
PMID 35973629
Discovery of bakuchiol as an AIM2 inflammasome activator and cause of hepatotoxicity
J Ethnopharmacol · 2022
⚗️ All Ingredient data fields for Bakuchiol
⚗️ Identity
Name
Bakuchiol
Aliases / Synonyms
10309-37-2; (S)-Bakuchiol; (+)-Bakuchiol; Sytenol a; 4-(3-Ethenyl-3,7-dimethyl-1,6-octadienyl)phenol; (S)-(+)-Bakuchiol; UNII-OT12HJU3AR; OT12HJU3AR; UP-256
🧪 Chemistry
Molecular Weight
256.3890
LogP
5.3441
Drug-likeness
0.681
H-Bond Acceptors
1
H-Bond Donors
1
Rotatable Bonds
6
🔬 Structures
Canonical SMILES
CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C
Isomeric SMILES
CC(=CCC[C@@](C)(C=C)/C=C/C1=CC=C(C=C1)O)C
InChIKey
LFYJSSARVMHQJB-QIXNEVBVSA-N
InChI
InChI=1S/C18H24O/c1-5-18(4,13-6-7-15(2)3)14-12-16-8-10-17(19)11-9-16/h5,7-12,14,19H,1,6,13H2,2-4H3/b14-12+/t18-/m1/s1
🔗 External References
HERB DB
HBIN017546 ↗
PubChem CID
5468522 ↗
CAS Number
10309-37-2 ↗
NPASS
NPC98772
HIT
C0509
TCMID
23596
TCM-ID
6433
🔍 Raw view — every non-empty column on this row (31 fields)
name
Bakuchiol
common names
10309-37-2; (S)-Bakuchiol; (+)-Bakuchiol; Sytenol a; 4-(3-Ethenyl-3,7-dimethyl-1,6-octadienyl)phenol; (S)-(+)-Bakuchiol; UNII-OT12HJU3AR; OT12HJU3AR; UP-256
herb ingredient id
HBIN017546
canonical smiles
CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C
isomeric smiles
CC(=CCC[C@@](C)(C=C)/C=C/C1=CC=C(C=C1)O)C
inchi
InChI=1S/C18H24O/c1-5-18(4,13-6-7-15(2)3)14-12-16-8-10-17(19)11-9-16/h5,7-12,14,19H,1,6,13H2,2-4H3/b14-12+/t18-/m1/s1
inchikey
LFYJSSARVMHQJB-QIXNEVBVSA-N
mol wt
256.3890
num h acceptors
1
num h donors
1
mol logp
5.3441
num rotatable bonds
6
drug likeness
0.681
cas id
10309-37-2
tcmid ingredient id
23596
tcm id ingredient id
6433
pubchem cid
5468522
npass id
NPC98772
hit id
C0509

🏥 Linked Health Topics

1 · studied for these conditions (text bridge)
Acne Vulgaris
syndrome

📋 Clinical Trials

2 · subject of clinical study
NCT03112863 Comparison of the Cosmetic Effects of Bakuchiol and Retinol
→ Wrinkle|Photoaging
NCT05069272 Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bak
→ Acne Vulgaris

📚 PubMed References

3 · cited research
PMID 32499702 Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP
Front Pharmacol
PMID 33062139 Bakuchiol Alleviates Hyperglycemia-Induced Diabetic Cardiomyopathy by Reducing M
Oxid Med Cell Longev
PMID 35973629 Discovery of bakuchiol as an AIM2 inflammasome activator and cause of hepatotoxi
J Ethnopharmacol
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables