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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Beta-glucan

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Beta-glucan

Measures of appetite and satiety including ad libitum energy 1 Healthy 1 Measures of appetite and satiety including ad libitum energy 1 Diet, Healthy|Blood Sugar; High|Diabetes|Appetite and Genera 1 Losing weight by fibre supplementation. 1 Functional food and glucose metabolism. 1 Cardiovascular diseases (CVD) have been an important cause o 1 Cancer. 1 Any human health condition 1 Upper Respiratory Tract Infections|Mental Stress 1 Neuroblastoma|High-risk Neuroblastoma|Metastatic Neuroblasto 1 Upper respiratory tract infection (URTI) includes a series o 1

📋 Sample Trials

NCT05177172

Effect of Oat Compounds on Postprandial Glucose Response

Completed

NCT06083350

Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment

Active_Not_Recruiting

NCT06146322

Barley Beta-glucan, Glycemic Control, and Appetite

Completed

📊 Sample Meta-Analyses

CRD42022311145

Effect of dietary oat beta-glucan intake on lipid profiles in hypercholesterolaemic adults,A meta-analysis of randomized controlled trials

Cardiovascular diseases (CVD) have been an important cause of human death for de

CRD42016043539

Effectiveness and safety of commercial beta-glucan products for oral and inhalation use: a systematic review of randomized controlled trials

Any human health condition

CRD42019136140

Effects of beta-glucan supplementation on energy intake and appetite: a systematic review of controlled clinical trials

Measures of appetite and satiety including ad libitum energy intake, subjective

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Beta-glucan

⚗️ Identity

Name

Beta-glucan

Aliases / Synonyms

9041-22-9; beta-D-Glucan; beta-Glucans; beta-Glucosylglucan; Epiglucan; CCRIS 8998; (2S,3R,4S,5S,6R)-2-[(2R,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; UNII-44FQ49X6UN; 44FQ49X6UN

🧪 Chemistry

Molecular Weight

504.4380

LogP

-7.5730

Drug-likeness

0.154

Oral Bioavailability

0.7320

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O

Isomeric SMILES

C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)O)O

InChIKey

FYGDTMLNYKFZSV-URKRLVJHSA-N

InChI

InChI=1S/C18H32O16/c19-1-4-7(22)8(23)12(27)17(31-4)34-15-6(3-21)32-18(13(28)10(15)25)33-14-5(2-20)30-16(29)11(26)9(14)24/h4-29H,1-3H2/t4-,5-,6-,7-,8+,9-,10-,11-,12-,13-,14?,15?,16+,17+,18+/m1/s1

🔗 External References

HERB DB

HBIN018129 ↗

PubChem CID

439262 ↗

CAS Number

9051-97-2 ↗

SymMap

2912

TCMSP

MOL000278

🔍 Raw view — every non-empty column on this row (30 fields)

name

Beta-glucan

common names

herb ingredient id

HBIN018129

canonical smiles

C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O

isomeric smiles

C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)O)O

inchi

InChI=1S/C18H32O16/c19-1-4-7(22)8(23)12(27)17(31-4)34-15-6(3-21)32-18(13(28)10(15)25)33-14-5(2-20)30-16(29)11(26)9(14)24/h4-29H,1-3H2/t4-,5-,6-,7-,8+,9-,10-,11-,12-,13-,14?,15?,16+,17+,18+/m1/s1

inchikey

FYGDTMLNYKFZSV-URKRLVJHSA-N

mol wt

504.4380

num h acceptors

num h donors

mol logp

-7.5730

num rotatable bonds

drug likeness

0.154

ob score

0.7320

cas id

9051-97-2

symmap mol id

2912

tcmsp ingredient id

MOL000278

pubchem cid

439262

📋 Clinical Trials

6 · subject of clinical study

NCT05177172 Effect of Oat Compounds on Postprandial Glucose Response

→ Healthy Subjects

NCT06083350 Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cogniti

→ Mild Cognitive Impairment|Alzheimer Disease

NCT06146322 Barley Beta-glucan, Glycemic Control, and Appetite

→ Diet, Healthy|Blood Sugar; High|Diabetes|Appetite

NCT05917015 A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or

→ Upper Respiratory Tract Infections|Mental Stress

NCT05801653 Health Effects of Oat Bioactives (Betaglucan) in Human

→ Healthy

NCT06057948 A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastom

→ Neuroblastoma|High-risk Neuroblastoma|Metastatic N

📊 Meta-Analyses

10 · systematic review

CRD42022311145 Effect of dietary oat beta-glucan intake on lipid profiles in hypercholesterolae

→ Cardiovascular diseases (CVD) have been an importa

CRD42016043539 Effectiveness and safety of commercial beta-glucan products for oral and inhalat

→ Any human health condition

CRD42019136140 Effects of beta-glucan supplementation on energy intake and appetite: a systemat

→ Measures of appetite and satiety including ad libi

CRD42020151539 Fungal beta-glucans as adjuvants for treating cancer patients - a systematic rev

→ Cancer.

CRD42020154183 Oat Beta-Glucan and Postprandial Glycemia Outcomes: A Systematic Review and Meta

→ Postprandial glucose and insulin responses

CRD42021226759 The effects of yeast beta-glucan on the prevention and treatment of upper respir

→ Upper respiratory tract infection (URTI) includes

CRD42015027988 The effect of products enriched with barley or beta-glucan extracted from barley

→ Functional food and glucose metabolism.

CRD42015023989 A systematic review on the effects of intake of beta-glucan on appetite and sati

→ Measures of appetite and satiety including ad libi

CRD42023411638 Impact of beta-glucan supplementation on obesity measures while following energy

→ Losing weight by fibre supplementation.

CRD42023437225 The effect of β-glucan on Colitis: A systematic review and meta-analysis of anim

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables