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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
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Ingredient
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Gene Target
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Betaine
2
Clinical Trials
0
Meta-Analyses
3
PubMed References
Top Conditions Studied with Betaine
📋 Sample Trials
NCT06042270
Firefighter Thermoregulatory Responses in Active Fire With Betaine Supplementation
Active_Not_Recruiting
NCT05790070
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle
Completed
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31255657
Investigation of betaine as a novel psychotherapeutic for schizophrenia
EBioMedicine · 2019
PMID 24819676
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease
Br J Pharmacol · 2014
PMID 26201319
Novel modulators of hepatosteatosis, inflammation and fibrogenesis
Hepatol Int · 2014
⚗️ All Ingredient data fields for Betaine
⚗️ Identity
Name
Betaine
Aliases / Synonyms
107-43-7; glycine betaine; oxyneurine; Trimethylglycine; lycine; Abromine; Trimethylglycocoll; Glycocoll betaine; Glycylbetaine
🧪 Chemistry
Molecular Weight
117.1480
LogP
-1.5575
Drug-likeness
0.41
Oral Bioavailability
40.9220
H-Bond Acceptors
2
Rotatable Bonds
2
🔬 Structures
Canonical SMILES
C[N+](C)(C)CC(=O)[O-]
Isomeric SMILES
C[N+](C)(C)CC(=O)[O-]
InChIKey
KWIUHFFTVRNATP-UHFFFAOYSA-N
InChI
InChI=1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
🔗 External References
HERB DB
PubChem CID
CAS Number
DrugBank
NPASS
NPC193154
SymMap
42
TCMID
23051
TCMSP
MOL000430; MOL002346
TCM-ID
6277
🔍 Raw view — every non-empty column on this row (34 fields)
name
Betaine
common names
107-43-7; glycine betaine; oxyneurine; Trimethylglycine; lycine; Abromine; Trimethylglycocoll; Glycocoll betaine; Glycylbetaine
herb ingredient id
HBIN018163
canonical smiles
C[N+](C)(C)CC(=O)[O-]
isomeric smiles
C[N+](C)(C)CC(=O)[O-]
inchi
InChI=1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
inchikey
KWIUHFFTVRNATP-UHFFFAOYSA-N
mol wt
117.1480
num h acceptors
2
num h donors
0
mol logp
-1.5575
num rotatable bonds
2
drug likeness
0.41
ob score
40.9220
cas id
107-43-7
symmap mol id
42
tcmid ingredient id
23051
tcmsp ingredient id
MOL000430; MOL002346
tcm id ingredient id
6277
pubchem cid
247
drugbank id
DB06756
npass id
NPC193154
📋 Clinical Trials
2 · subject of clinical studyNCT06042270 Firefighter Thermoregulatory Responses in Active Fire With Betaine Supplementati
→ Body Temperature Changes|Body Water Dehydration|In
NCT05790070 Potential Synergistic Effect of Combined Blood Flow Restriction Training and Bet
→ Blood Flow Restriction Training|Betaine Supplement
📚 PubMed References
3 · cited researchPMID 31255657 Investigation of betaine as a novel psychotherapeutic for schizophrenia
EBioMedicine
PMID 24819676 Rectification of impaired adipose tissue methylation status and lipolytic respon
Br J Pharmacol
PMID 26201319 Novel modulators of hepatosteatosis, inflammation and fibrogenesis
Hepatol Int
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
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target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables