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Disease
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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
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⚗️ Ingredient

Butanedioic acid

Open on HERB 2.0 ↗
21
Clinical Trials
0
Meta-Analyses
0
PubMed References
Top Conditions Studied with Butanedioic acid
Urinary Bladder, Overactive 4 Ureteral Stent|Stent Related Symptoms 1 Flank Pain|Urinary Bladder, Overactive 1 Phase 1|Healthy|Benign Prostatic Hyperplasia|Lower Urinary T 1 Benign Prostatic Hyperplasia|Benign Prostatic Hypertrophy|Ov 1 Pharmacokinetics of Solifenacin Succinate|Healthy Volunteers 1 Overactive Bladder|Urinary Incontinence|Urge Incontinence 1 Overactive Bladder|Benign Prostate Hyperplasia|Transurethral 1 Overactive Bladder in Parkinson's Disease 1 Urologic Diseases|Urinary Bladder, Overactive|Urinary Bladde 1 Overactive Bladder 1 Urologic Diseases|Urinary Bladder Diseases|Urological Manife 1
📋 Sample Trials
NCT01018264
Solifenacin Succinate (VESIcare) for the Treatment of Overactive Bladder in Parkinson's Disease
Completed · Phase 4
NCT00189800
A Study of Solifenacin Succinate Compared to Tolterodine in Patients With Overactive Bladder
Completed · Phase 3
NCT00337558
A Study of Solifenacin With Bladder Training Versus Solifenacin Alone in Patients With Overactive Bladder (SOLAR)
Completed · Phase 4
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Butanedioic acid
⚗️ Identity
Name
Butanedioic acid
Aliases / Synonyms
succinic acid; 110-15-6; Amber acid; Asuccin; Dihydrofumaric acid; Wormwood acid; Katasuccin; Bernsteinsaure; 1,2-Ethanedicarboxylic acid
🧪 Chemistry
Molecular Weight
118.0880
LogP
-0.0642
Drug-likeness
0.544
H-Bond Acceptors
2
H-Bond Donors
2
Rotatable Bonds
3
🔬 Structures
Canonical SMILES
C(CC(=O)O)C(=O)O
Isomeric SMILES
C(CC(=O)O)C(=O)O
InChIKey
KDYFGRWQOYBRFD-UHFFFAOYSA-N
InChI
InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
🔗 External References
HERB DB
HBIN019068 ↗
PubChem CID
1110 ↗
DrugBank
DB00139 ↗
SymMap
18600
TCMID
24383
TCM-ID
6060
🔍 Raw view — every non-empty column on this row (30 fields)
name
Butanedioic acid
common names
succinic acid; 110-15-6; Amber acid; Asuccin; Dihydrofumaric acid; Wormwood acid; Katasuccin; Bernsteinsaure; 1,2-Ethanedicarboxylic acid
herb ingredient id
HBIN019068
canonical smiles
C(CC(=O)O)C(=O)O
isomeric smiles
C(CC(=O)O)C(=O)O
inchi
InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
inchikey
KDYFGRWQOYBRFD-UHFFFAOYSA-N
mol wt
118.0880
num h acceptors
2
num h donors
2
mol logp
-0.0642
num rotatable bonds
3
drug likeness
0.544
symmap mol id
18600
tcmid ingredient id
24383
tcm id ingredient id
6060
pubchem cid
1110
drugbank id
DB00139

🏥 Linked Health Topics

1 · studied for these conditions (text bridge)
Overactive Bladder
syndrome

📋 Clinical Trials

12 · subject of clinical study
NCT01018264 Solifenacin Succinate (VESIcare) for the Treatment of Overactive Bladder in Park
→ Overactive Bladder in Parkinson's Disease
NCT00189800 A Study of Solifenacin Succinate Compared to Tolterodine in Patients With Overac
→ Overactive Bladder
NCT00337558 A Study of Solifenacin With Bladder Training Versus Solifenacin Alone in Patient
→ Overactive Bladder|Urinary Incontinence|Urge Incon
NCT00573508 Study of VESIcare® In Overactive Bladder (OAB) Subjects to Evaluate Symptom Both
→ Urinary Bladder, Overactive
NCT00629642 Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to
→ Multiple Sclerosis|Neurogenic Bladder|Spinal Cord
NCT00771394 Solifenacin as Add-on Therapy for Overactive Bladder Symptoms in Men Treated for
→ Benign Prostatic Hyperplasia|Benign Prostatic Hype
NCT00801944 Solifenacin Succinate 5mg or 10mg Once Daily in the Treatment of Urgency Symptom
→ Urinary Bladder, Overactive
NCT00802373 Solifenacin Succinate Versus Tolterodine 4mg Once Daily
→ Urinary Bladder, Overactive
NCT01262391 Single-dose Study to Assess Pharmacokinetics of Solifenacin Succinate Suspension
→ Urinary Bladder, Overactive
NCT01340027 A Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Soli
→ Urologic Diseases|Urinary Bladder Diseases|Urologi
NCT01381120 Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pai
→ Flank Pain|Urinary Bladder, Overactive
NCT01406158 A Study in Healthy Volunteers Comparing Two Different Liquid Formulations of Sol
→ Pharmacokinetics of Solifenacin Succinate|Healthy
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables