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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

18beta-glycyrrhetinic acid

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with 18beta-glycyrrhetinic acid

Unipolar Depression 1 Periodontal Surgery 1

📋 Sample Trials

NCT05570110

Enoxolone in Major Depression - Biomarker-outcome Relationship

Recruiting · Phase 1|Phase 2

NCT05987722

Effectiveness of Enoxolone on Oral Conditions of Patients With Periodontal Surgery

Completed

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for 18beta-glycyrrhetinic acid

⚗️ Identity

Name

18beta-glycyrrhetinic acid

Aliases / Synonyms

enoxolone; 471-53-4; Glycyrrhetic acid; GLYCYRRHETINIC ACID; Uralenic acid; 18-beta-Glycyrrhetinic acid; Rhetinic Acid; Glycyrrhetin; Biosone

🧪 Chemistry

Molecular Weight

470.6940

LogP

6.4126

Drug-likeness

0.464

Oral Bioavailability

22.0530

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C

Isomeric SMILES

C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

InChIKey

MPDGHEJMBKOTSU-YKLVYJNSSA-N

InChI

InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1

🔗 External References

HERB DB

PubChem CID

CAS Number

DrugBank

NPASS

NPC233455

HIT

C0044

SymMap

577

TCMID

23092

TCMSP

MOL004804

TCM-ID

12218

🔍 Raw view — every non-empty column on this row (35 fields)

name

18beta-glycyrrhetinic acid

common names

enoxolone; 471-53-4; Glycyrrhetic acid; GLYCYRRHETINIC ACID; Uralenic acid; 18-beta-Glycyrrhetinic acid; Rhetinic Acid; Glycyrrhetin; Biosone

herb ingredient id

HBIN002095

canonical smiles

CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C

isomeric smiles

C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

inchi

inchikey

MPDGHEJMBKOTSU-YKLVYJNSSA-N

mol wt

470.6940

num h acceptors

num h donors

mol logp

6.4126

num rotatable bonds

drug likeness

0.464

ob score

22.0530

cas id

471-53-4

symmap mol id

577

tcmid ingredient id

23092

tcmsp ingredient id

MOL004804

tcm id ingredient id

12218

pubchem cid

10114

drugbank id

DB13089

npass id

NPC233455

hit id

C0044

🏥 Linked Health Topics

1 · diseases via target pathways

Unipolar Depression

disease

📋 Clinical Trials

2 · subject of clinical study

NCT05570110 Enoxolone in Major Depression - Biomarker-outcome Relationship

→ Unipolar Depression

NCT05987722 Effectiveness of Enoxolone on Oral Conditions of Patients With Periodontal Surge

→ Periodontal Surgery

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables