Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿

Herb

→

→

→

→

🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Cisplatin

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Cisplatin

Nasopharyngeal Carcinoma 2 Locally Advanced Cervical Cancer|Gemcitabine|Chemo-radiother 1 Malignant pleural effusion is a common complication of advan 1 Advanced Cholangiocarcinoma 1 Urinary Bladder Cancer 1 Locally Advanced Cervical Cancer 1 Lung cancer is the malignant tumor with the highest incidenc 1 Advanced Biliary Tract Cancer 1 Unresectable Intrahepatic Cholangiocarcinoma 1 High-grade Salivary Gland Carcinoma 1 Induction chemotherapy (IC) followed by concurrent chemoradi 1 The Efficacy and Safety of Therapy Efficacy for Locally Adva 1

📋 Sample Trials

NCT06095141

Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Deficiency

Recruiting · Phase 2|Phase 3

NCT05823311

Lenvatinib, Tislelizumab Combined With Gemcitabine and Cisplatin (GPLET) in the Treatment of Advanced Cholangiocarcinoma

Recruiting · Phase 3

NCT06145412

A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer

Active_Not_Recruiting · Phase 2

📊 Sample Meta-Analyses

CRD42015017019

Concurrent chemoradiotherapy with weekly versus three-weekly cisplatin in locally advanced head and neck squamous cell carcinoma [Cochrane Protocol]

The Cochrane Ear, Nose and Throat Disorders Group

CRD42015019520

Radiation concomitant chemotherapy for head and neck cancer: is cisplatin more effective than carboplatin - a meta-analysis

Head and neck cancer are common in countries such as Brazil. It is related to lo

CRD42019123716

Comparison between fluoropyrimidine-cisplatin and gemcitabine-cisplatin as first-line chemotherapy for advanced biliary tract cancer: a meta-analysis

Advanced biliary tract cancer (cholangiocarcinoma or gallbladder cancer)

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Cisplatin

⚗️ Identity

Name

Cisplatin

Aliases / Synonyms

cisplatin; 14913-33-8; trans-Dichlorodiamineplatinum(II); azane;dichloroplatinum; Platinum, diamminedichloro-, (SP-4-1)-; trans-Diamminedichloro platinum(II); MFCD00011623; trans-Platinum(II)diammine dichloride; CACP; trans-Dichlorodiamineplatinum(II);Transplatin

🧪 Chemistry

Molecular Weight

300.0460

LogP

1.7005

Drug-likeness

0.715

H-Bond Acceptors

H-Bond Donors

🔬 Structures

Canonical SMILES

N.N.Cl[Pt]Cl

Isomeric SMILES

N.N.Cl[Pt]Cl

InChIKey

LXZZYRPGZAFOLE-UHFFFAOYSA-L

InChI

InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

🔗 External References

HERB DB

HBIN020917 ↗

PubChem CID

5702198 ↗

TCM-ID

22135

🔍 Raw view — every non-empty column on this row (27 fields)

name

Cisplatin

common names

herb ingredient id

HBIN020917

canonical smiles

N.N.Cl[Pt]Cl

isomeric smiles

N.N.Cl[Pt]Cl

inchi

InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

inchikey

LXZZYRPGZAFOLE-UHFFFAOYSA-L

mol wt

300.0460

num h acceptors

num h donors

mol logp

1.7005

num rotatable bonds

drug likeness

0.715

tcm id ingredient id

22135

pubchem cid

5702198

🏥 Linked Health Topics

6 · studied for these conditions (text bridge)

Cholangiocarcinoma

disease

High-Grade Salivary Gland Carcinoma

disease

Cholangiocarcinoma Non-Resectable

disease

Nasopharyngeal Carcinoma

disease

Unresectable Intrahepatic Cholangiocarcinoma

disease

Advanced Urothelial Carcinoma

disease

📋 Clinical Trials

12 · subject of clinical study

NCT06095141 Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Defici

→ Pancreatic Adenocarcinoma|Homologous Recombination

NCT05823311 Lenvatinib, Tislelizumab Combined With Gemcitabine and Cisplatin (GPLET) in the

→ Advanced Cholangiocarcinoma

NCT06145412 A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in Peop

→ Head and Neck Cancer

NCT06091124 Neoadjuvant Adebrelimab Plus Etoposide and Cisplatin in Neuroendocrine Bladder C

→ Neuroendocrine Carcinoma of the Bladder|Bladder Ca

NCT05746598 Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity t

→ Non Small Cell Lung Cancer|Nephropathy|Cardiotoxic

NCT05812430 Anlotinib Plus TQB2450 Combined With Nab-paclitaxel and Cisplatin as First-line

→ Advanced Biliary Tract Cancer

NCT05822934 Carboplatin-gemcitabine Versus Cisplatin- Gemcitabine as Neoadjuvant Chemotherap

→ Urinary Bladder Cancer

NCT05727410 Neoadjuvant Nivolumab, Docetaxel, Cisplatin Therapy Followed by Surgery and Radi

→ High-grade Salivary Gland Carcinoma

NCT05947201 Neoadjuvant Treatment of Cadonilimab Combined Albumin-paclitaxel, Cisplatin and

→ The Efficacy and Safety of Therapy Efficacy for Lo

NCT05738057 Combined Therapy Using D-TACE, Gemcitabine and Cisplatin, and PD1 Antibody in Ad

→ Unresectable Intrahepatic Cholangiocarcinoma

NCT06055738 Zimberelimab Combined With Albumin-bound Paclitaxel and Cisplatin in Neoadjuvant

→ Locally Advanced Cervical Cancer

NCT05967182 A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperat

→ Cholangiocarcinoma

📊 Meta-Analyses

12 · systematic review

CRD42015017019 Concurrent chemoradiotherapy with weekly versus three-weekly cisplatin in locall

→ The Cochrane Ear, Nose and Throat Disorders Group

CRD42015019520 Radiation concomitant chemotherapy for head and neck cancer: is cisplatin more e

→ Head and neck cancer are common in countries such

CRD42019123716 Comparison between fluoropyrimidine-cisplatin and gemcitabine-cisplatin as first

→ Advanced biliary tract cancer (cholangiocarcinoma

CRD42019152184 The efficacy of cisplatin for the treatment of patients with oral cancer (OC): a

→ Oral cancer; cisplatin.

CRD42019156558 Efficacy and safety of cisplatin for the management of adult patients with oral

→ Oral cancer; cisplatin

CRD42020163503 The optimal Chinese herbal injections for use with taxol plus cisplatin for trea

→ non-small cell lung cancer

CRD42020176544 Lentinan combined with cisplatin for intrathoracic injection of lung cancer:a sy

→ Oncology

CRD42020196422 Comparision of oncologic outcomes associated with neoadjuvant chemotherapy Dose

→ Muscle invasive bladder cancer

CRD42021252279 Network meta-analysis of six kinds of traditional Chinese medicine injections co

→ Lung cancer is the malignant tumor with the highes

CRD42021270838 A Systematic Review And Meta-Analysis of Concurrent Chemoradiotherapy With Singl

→ Concurrent chemoradiotherapy (CCRT) based on cispl

CRD42021285275 Intrapleural perfusion with Chinese herbal injections as adjuvant for cisplatin

→ MPE is one of the most common complications of adv

CRD42021291747 A Meta-Analysis of Concurrent Cisplatin Chemoradiotherapy followed by consolidat

→ Current standard treatment for patients with cervi

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables