Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿

Herb

→

→

→

→

🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Cis-resveratrol

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

124

PubMed References

Top Conditions Studied with Cis-resveratrol

📋 Sample Trials

NCT06020313

Autonomic and Cardiovascular Recovery After the Acute Use of Resveratrol in Overweight and Obesity Individuals

Recruiting

NCT05874882

Evaluating the Efficacy of Resveratrol Containing Mouthwash as Adjunct Treatment Periodontitis:

Recruiting · Early_Phase 1

NCT05808387

The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers

Recruiting

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

PMID 31233775

The hepatic-targeted, resveratrol loaded nanoparticles for relief of high fat diet-induced nonalcoholic fatty liver disease

J Control Release · 2019

PMID 30026862

Comparative profiling of analog targets: a case study on resveratrol for mouse melanoma metastasis suppression

Theranostics · 2018

PMID 28950914

Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway

J Exp Clin Cancer Res · 2017

⚗️ All Ingredient data fields for Cis-resveratrol

⚗️ Identity

Name

Cis-resveratrol

Aliases / Synonyms

(Z)-resveratrol; 61434-67-1; Cis resveratrol; Resveratrol, (Z)-; 5-[(Z)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol; 5-[(Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol; cis-3,4',5-trihydroxystilbene; (Z)-3,5,4'-trihydroxystilbene; Resveratrol (Z)-form [MI]

🧪 Chemistry

Molecular Weight

228.2470

LogP

2.9738

Drug-likeness

0.692

Oral Bioavailability

41.1270

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O

Isomeric SMILES

C1=CC(=CC=C1/C=C\C2=CC(=CC(=C2)O)O)O

InChIKey

LUKBXSAWLPMMSZ-UPHRSURJSA-N

InChI

InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1-

🔗 External References

HERB DB

HBIN020921 ↗

PubChem CID

1548910 ↗

CAS Number

501-36-0 ↗

NPASS

NPC248573

SymMap

3678

TCMSP

MOL001229

🔍 Raw view — every non-empty column on this row (31 fields)

name

Cis-resveratrol

common names

herb ingredient id

HBIN020921

canonical smiles

C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O

isomeric smiles

C1=CC(=CC=C1/C=C\C2=CC(=CC(=C2)O)O)O

inchi

InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1-

inchikey

LUKBXSAWLPMMSZ-UPHRSURJSA-N

mol wt

228.2470

num h acceptors

num h donors

mol logp

2.9738

num rotatable bonds

drug likeness

0.692

ob score

41.1270

cas id

501-36-0

symmap mol id

3678

tcmsp ingredient id

MOL001229

pubchem cid

1548910

npass id

NPC248573

🏥 Linked Health Topics

2 · studied for these conditions (text bridge)

📋 Clinical Trials

8 · subject of clinical study

NCT06020313 Autonomic and Cardiovascular Recovery After the Acute Use of Resveratrol in Over

→ Polyphenols|Cardiovascular Diseases|Autonomic Nerv

NCT05874882 Evaluating the Efficacy of Resveratrol Containing Mouthwash as Adjunct Treatment

→ Periodontitis

NCT05808387 The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers

→ Coronary Artery Disease|Menopause|Endothelial Dysf

NCT05981053 Biological Effects in Consumers of Resveratrol-enriched Wine

→ Aging|Healthy Aging|Sarcopenia|Obesity

NCT06095635 Acute Influence of Resveratrol Supplementation and Beet Extract in Recovery Afte

→ Coronary Artery Disease|Autonomic Nervous System D

NCT05761327 Investigation of the Effects of Curcumin and Resveratrol Supplements Added to th

→ Ulcerative Colitis

NCT05684848 Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre

→ Wheezing|Recurrent Respiratory Tract Infections

NCT06131918 Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabe

→ Peripheral Diabetic Neuropathy

📚 PubMed References

12 · cited research

PMID 31233775 The hepatic-targeted, resveratrol loaded nanoparticles for relief of high fat di

J Control Release

PMID 30026862 Comparative profiling of analog targets: a case study on resveratrol for mouse m

Theranostics

PMID 28950914 Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA dam

J Exp Clin Cancer Res

PMID 24442997 CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by S

Hepatology

PMID 24145604 Resveratrol attenuates vascular endothelial inflammation by inducing autophagy t

Autophagy

PMID 23856934 Resveratrol stimulates sphingosine-1-phosphate signaling of cathelicidin product

J Invest Dermatol

PMID 25677910 Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role o

Aging Cell

PMID 27048804 Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by

mBio

PMID 22561641 Impaired adenosine monophosphate-activated protein kinase signalling in dorsal r

Brain

PMID 23486084 Neurodegeneration in streptozotocin-induced diabetic rats is attenuated by treat

Neuroendocrinology

PMID 21278141 Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice throu

Cardiovasc Res

PMID 26891034 Identification of sirtuin 1 as a promising therapeutic target for hypertrophic s

Br J Pharmacol

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables