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Disease
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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Creatinine
10
Clinical Trials
17
Meta-Analyses
0
PubMed References
Top Conditions Studied with Creatinine
Paraquat (PQ, 1, 1′-dimethyl-4, 4′-bipyridinium dichloride) 2
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurod 1
Chronic Kidney Diseases|Acute Kidney Injury 1
Renal diseases (both acute and chronic) and generic markers 1
Adverse maternal-perinatal outcomes in preeclampsia regardin 1
Cancer 1
Premature rupture of membranes (PROM) occurs in 10% of all p 1
Acute kidney injury (AKI) is a syndrome characterized by a r 1
Performance of CKD-EPI and MDRD formulas in assessing estima 1
Urolithiasis|Hyperoxaluria 1
Surgery|Malignancy|Acute Kidney Injury|Cronich Kidney Diseas 1
Kidney function, contrast-induced acute kidney injury. 1
📋 Sample Trials
NCT00323128
Validation of Serum Creatinine Dosage and Renal Clearance
Completed · Phase 1
NCT03814057
Creatinine Height Index in Elderly
Completed
NCT04341974
Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury
Completed
📊 Sample Meta-Analyses
CRD42017076329
Relationship between Cognitive Impairment and Serum Creatinine Level of the Elderly: A meta-analysis
Cognitive impairment, or Cognitive deficit, is an inclusive term to describe any
CRD42018105840
Serum creatinine for predicting mortality after acute paraquat poisoning: a meta-analysis
Paraquat (PQ, 1, 1′-dimethyl-4, 4′-bipyridinium dichloride) is a quaternary nitr
CRD42018110879
Increased spot urine albumin-to-creatinine ratio and stroke incidence in general population: a systematic review and meta-analysis
Stroke and early sign of renal dysfunction
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Creatinine
⚗️ Identity
Name
Creatinine
Aliases / Synonyms
60-27-5; AYI8EX34EU; 2-Imino-1-methylimidazolidin-4-one; 1-Methylglycocyamidine; 1-Methylhydantoin-2-imide; Kreatinin; Creatinine,heated; Kreatininum; 2-amino-3-methyl-4H-imidazol-5-one
🧪 Chemistry
Molecular Weight
113.1200
LogP
-1.2269
Drug-likeness
0.428
H-Bond Acceptors
3
H-Bond Donors
1
🔬 Structures
Canonical SMILES
CN1CC(=O)N=C1N
Isomeric SMILES
CN1CC(=O)N=C1N
InChIKey
DDRJAANPRJIHGJ-UHFFFAOYSA-N
InChI
InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
🔗 External References
🔍 Raw view — every non-empty column on this row (28 fields)
name
Creatinine
common names
60-27-5; AYI8EX34EU; 2-Imino-1-methylimidazolidin-4-one; 1-Methylglycocyamidine; 1-Methylhydantoin-2-imide; Kreatinin; Creatinine,heated; Kreatininum; 2-amino-3-methyl-4H-imidazol-5-one
herb ingredient id
HBIN021665
canonical smiles
CN1CC(=O)N=C1N
isomeric smiles
CN1CC(=O)N=C1N
inchi
InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
inchikey
DDRJAANPRJIHGJ-UHFFFAOYSA-N
mol wt
113.1200
num h acceptors
3
num h donors
1
mol logp
-1.2269
num rotatable bonds
0
drug likeness
0.428
tcmid ingredient id
4223
pubchem cid
588
npass id
NPC27836
🏥 Linked Health Topics
1 · diseases via target pathways📋 Clinical Trials
10 · subject of clinical studyNCT00323128 Validation of Serum Creatinine Dosage and Renal Clearance
→ Kidney Failure
NCT03814057 Creatinine Height Index in Elderly
→ Malnutrition in Elderly
NCT04341974 Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury
→ Surgery|Malignancy|Acute Kidney Injury|Cronich Kid
NCT04368325 Low Creatinine Level and Respiratory Failure
→ Intensive Care Unit|Respiratory Insufficiency|Musc
NCT04571359 Spot Urine Oxalate to Creatinine Ratio and 24 Hours Urinary Oxalate
→ Urolithiasis|Hyperoxaluria
NCT00607529 Clinical Evaluation of an Investigational Blood Creatinine Point-of-Care Test De
→ Cancer
NCT02111148 Vaginal Fluid Wash in Pre-labour Rupture of Membranes
→ Disorder of Amniotic Cavity and/or Membrane
NCT04612595 The Association Between sUCR and the Survival in Patients With DKD
→ Diabetic Kidney Disease
NCT05118074 Nova Max Creatinine and eGFR Meter System
→ Chronic Kidney Diseases|Acute Kidney Injury
NCT05144971 StatStrip A Glucose/Creatinine Meter System Lay User Study Evaluation
→ Diabete Mellitus|CKD|ESRD
📊 Meta-Analyses
12 · systematic reviewCRD42017076329 Relationship between Cognitive Impairment and Serum Creatinine Level of the Elde
→ Cognitive impairment, or Cognitive deficit, is an
CRD42018105840 Serum creatinine for predicting mortality after acute paraquat poisoning: a meta
→ Paraquat (PQ, 1, 1′-dimethyl-4, 4′-bipyridinium di
CRD42018110879 Increased spot urine albumin-to-creatinine ratio and stroke incidence in general
→ Stroke and early sign of renal dysfunction
CRD42018112909 Creatinine levels in patients with amyotrophic lateral sclerosis: a meta-analysi
→ Amyotrophic lateral sclerosis (ALS) is an adult-on
CRD42018115818 Point-of-care creatinine tests to assess kidney function before administering in
→ Kidney function, contrast-induced acute kidney inj
CRD42019118840 Evaluation of the diagnostic performance of creatinine compared with urine outpu
→ Acute kidney injury (AKI) is a syndrome characteri
CRD42019121598 Role of endogenous biomarkers Cystatin C compared to Creatinine among diabetic C
→ To evaluate the role of endogenous bio-markers (Cy
CRD42019141788 Laboratory critical risk alert thresholds for creatinine results requiring immed
→ Renal diseases (both acute and chronic) and generi
CRD42020141800 Vaginal fluid urea and creatinine in the diagnosis of premature rupture of membr
→ Premature rupture of membranes (PROM) occurs in 10
CRD42020172602 What is the accuracy of albumin:creatinine ratio versus protein:creatinine ratio
→ Chronic Kidney Disease
CRD42021236613 Evaluation of the creatinine-based CKD-EPI and MDRD equations in estimating the
→ Performance of CKD-EPI and MDRD formulas in assess
CRD42022335006 Serum creatinine in predicting mortality after paraquat poisoning ：a meta
→ Paraquat (PQ, 1, 1′-dimethyl-4, 4′-bipyridinium di
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables