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Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿
Herb
6,826
→
⚗️
Ingredient
44,595
→
🧬
Gene Target
15,505
→
🏥
Disease
30,170
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Abetalipoproteinemia Abortion, Habitual Agenesis Acanthamoeba Keratitis Acanthosis Nigricans Achondrogenesis Achondroplasia Acne Vulgaris Acne Keloid Apert Syndrome
🏥 Disease / Health Topic

Nicotine Dependence

Open on HERB 2.0 ↗
43
Clinical Trials
2
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT02102100
The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
Completed
NCT02592772
Manipulating Tobacco Constituents in Male Menthol Smokers
Completed
NCT02102100
The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
Completed
📊 Sample Meta-Analyses
CRD42018087663
Systematic review and meta-analysis of the effectiveness of virtual reality exposure therapy for the treatment of alcohol and nicotine dependence
alcohol and/or nicotine dependence.
CRD42021268682
E-Cigarettes and Nicotine Replacement Therapy for Smoking Cessation and Nicotine Abstinence: A Meta-Analysis of Randomized Controlled Trials
Tobacco and nicotine dependence
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Nicotine Dependence
🏥 Names
Disease Name
Nicotine Dependence
Alias Names
Nicotine Dependence; Nicotine Use Disorder; Tobacco Dependence
Topic Type
disease
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Mental or Behavioral Dysfunction
MeSH Class
Mental Disorders; Chemically-Induced Disorders
DO Class
disease of mental health
🔗 External References
HERB DB
HBDIS002132 ↗
MeSH
D014029 ↗
Disease Ontology
50742
DisGeNET
C0028043
🔍 Raw view — every non-empty column on this row (26 fields)
name
Nicotine Dependence
alias name
Nicotine Dependence; Nicotine Use Disorder; Tobacco Dependence
topic type
disease
disgenet disease type
disease
umls disease type
Mental or Behavioral Dysfunction
mesh disease class
Mental Disorders; Chemically-Induced Disorders
do disease class
disease of mental health
umls disease type id
T048
mesh disease class id
F03; C25
do disease class id
DOID:150
herb disease id
HBDIS002132
disgenet id
C0028043
mesh id
D014029
do id
50742

🌿 Related Herbs

1 · shared evidence
Menthol

⚗️ Related Ingredients

5 · shared evidence
Menthol
Nicotine
(?)-nicotine
Oxytocin
Progesterone

📋 Clinical Trials

12 · subject of clinical study
NCT02102100 The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirabili
→ Nicotine Dependence
NCT02592772 Manipulating Tobacco Constituents in Male Menthol Smokers
→ Nicotine Dependence
NCT02102100 The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirabili
→ Nicotine Dependence
NCT02102100 The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirabili
→ Nicotine Dependence
NCT00956943 Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine
→ Nicotine Dependence
NCT00960778 Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinize
→ Nicotine Dependence
NCT00969137 Sensitivity to Intravenous Nicotine: Genetic Moderators
→ Nicotine Dependence
NCT00996034 Nicotine Vaccination and Nicotinic Receptor Occupancy
→ Nicotine Dependence
NCT01034020 Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers
→ Substance Related Disorder|Nicotine Dependence
NCT01588561 Nicotine Related Brain Activity: The Influence of Smoking History and Blood Nico
→ Nicotine Dependence
NCT01664741 Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging
→ Nicotine Dependence
NCT02587312 Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers
→ Nicotine Dependence

📊 Meta-Analyses

2 · systematic review
CRD42018087663 Systematic review and meta-analysis of the effectiveness of virtual reality expo
→ alcohol and/or nicotine dependence.
CRD42021268682 E-Cigarettes and Nicotine Replacement Therapy for Smoking Cessation and Nicotine
→ Tobacco and nicotine dependence
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables