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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Enoxaparin

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Enoxaparin

Venous Thromboembolism 2 The condition to be studied is COVID-19, a novel highly infe 1 COVID-19|Deep Vein Thrombosis|Anticoagulants and Bleeding Di 1 Prevention of deep vein thrombosis and pulmonary embolism in 1 Acute Respiratory Failure|SARS CoV 2 Infection|Anticoagulant 1 VTE prophylaxis in obese post-caesarean women. 1 Patients undergoing total knee arthroplasty(TKA) are at high 1 Venous thromboembolism, anticoagulants 1 MPN is a group of heterogenous chronic hematologic malignanc 1 Venous thromboembolism (VTE) refers to a blood clot that sta 1 Hypercoagulability is a common cause of morbidity and mortal 1 Venous thromboembolism (VTE) poses a significant challenge a 1

📋 Sample Trials

NCT05225155

Effect of Prophylatic Use of Enoxaparin in Women Undergoing in Vitro Fertilization Treatment

Completed

NCT05334654

Bivalirudin Versus Enoxaparin in Critically Ill COVID-19 Patients

Completed

NCT05265676

Bioequivalence Study of a Generic Enoxaparin Sodium to Clexane® After Single Subcutaneous Dose in Healthy Human Subjects

Completed · Phase 1

📊 Sample Meta-Analyses

CRD42016039951

Apixaban versus enoxaparin for thromboprophylaxis in patients undergoing total knee replacement (TKR) and total hip replacement (THR)

Total knee replacement (TKR) is the treatment of choice in patients suffering fr

CRD42018090050

<div>The safety and effectiveness of enoxaparin and aspirin for extended venous thromboembolism prophylaxis after total hip and knee arthroplasty: a systematic review</div>

Prevention of deep vein thrombosis and pulmonary embolism in patients who have u

CRD42019104205

Comparison of direct oral anticoaugulants and enoxaparin for preventing major vascular events after total hip or knee replacement: a network meta-analysis

Total hip or knee replacement surgery, postoperative vascular events.

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Enoxaparin

⚗️ Identity

Name

Enoxaparin

Aliases / Synonyms

Clexane; Clivarin; Nadroparine; Ardeparin; Bemiparin; Certoparin; Clivarine; Dalteparin; Fraxiparin

🧪 Chemistry

Molecular Weight

1134.9340

LogP

-10.7119

Drug-likeness

0.047

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O

Isomeric SMILES

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O

InChIKey

HTTJABKRGRZYRN-UHFFFAOYSA-N

InChI

InChI=1S/C26H42N2O37S5/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36/h5-20,23-26,28-29,31-34,39H,2-3H2,1H3,(H,27,30)(H,35,36)(H,37,38)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)

🔗 External References

HERB DB

HBIN025099 ↗

PubChem CID

772 ↗

NPASS

NPC305261

TCMID

23123

🔍 Raw view — every non-empty column on this row (28 fields)

name

Enoxaparin

common names

Clexane; Clivarin; Nadroparine; Ardeparin; Bemiparin; Certoparin; Clivarine; Dalteparin; Fraxiparin

herb ingredient id

HBIN025099

canonical smiles

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O

isomeric smiles

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O

inchi

inchikey

HTTJABKRGRZYRN-UHFFFAOYSA-N

mol wt

1134.9340

num h acceptors

num h donors

mol logp

-10.7119

num rotatable bonds

drug likeness

0.047

tcmid ingredient id

23123

pubchem cid

772

npass id

NPC305261

🏥 Linked Health Topics

1 · diseases via target pathways

Venous Thromboembolism

phenotype

📋 Clinical Trials

5 · subject of clinical study

NCT05225155 Effect of Prophylatic Use of Enoxaparin in Women Undergoing in Vitro Fertilizati

→ Infertility, Female|Thrombophilia|Fertilization in

NCT05334654 Bivalirudin Versus Enoxaparin in Critically Ill COVID-19 Patients

→ Acute Respiratory Failure|SARS CoV 2 Infection|Ant

NCT05265676 Bioequivalence Study of a Generic Enoxaparin Sodium to Clexane® After Single Sub

→ Healthy

NCT05224388 Evaluating Dose Regimen of Intravenous Unfractionated Heparin and Low Molecular

→ COVID-19|Deep Vein Thrombosis|Anticoagulants and B

NCT05226793 Medication Use Evaluation for Enoxaparin in Hospitalized COVID-19 Patients

→ Venous Thromboembolism

📊 Meta-Analyses

12 · systematic review

CRD42016039951 Apixaban versus enoxaparin for thromboprophylaxis in patients undergoing total k

→ Total knee replacement (TKR) is the treatment of c

CRD42018090050 <div>The safety and effectiveness of enoxaparin and aspirin for extended venous

→ Prevention of deep vein thrombosis and pulmonary e

CRD42019104205 Comparison of direct oral anticoaugulants and enoxaparin for preventing major va

→ Total hip or knee replacement surgery, postoperati

CRD42020138958 A systematic review of economic evaluation of rivaroxaban versus enoxaparin for

→ Venous thromboembolism (VTE) refers to a blood clo

CRD42020153712 Enoxaparin vs unfractionated heparin for the prevention of venous thromboembolis

→ Venous thromboembolism

CRD42020156278 Enoxaparin versus unfractionated heparin during percutaneous coronary interventi

→ Coronary heart disease (CHD).

CRD42020179955 Efficacy and safety of enoxaparin or fondaparinux in COVID-19 patients: a living

→ The condition to be studied is COVID-19, a novel h

CRD42020220379 Prophylactic Enoxaparin Dosing by Anti-Xa trough levels in reducing Venous Throm

→ Venous thromboembolism (VTE) poses a significant c

CRD42021236062 Use of Enoxaparin (LMWH) and its efficacy in Neurosurgical Patients: literature

CRD42021266102 Efficacy and safety of enoxaparin versus new oral anticoagulants to prevent veno

→ Total hip replacement (THR) is an effective and co

CRD42021267438 Use of Enoxaparin (LMWH) and it’s efficacy in Trauma Patients - Should anti-fact

CRD42021270070 Enoxaparin and it’s efficacy in Spinal Surgical Patients – Should anti-factor Xa

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables