Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿

Herb

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🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Abetalipoproteinemia Abortion, Habitual Agenesis Acanthamoeba Keratitis Acanthosis Nigricans Achondrogenesis Achondroplasia Acne Vulgaris Acne Keloid Apert Syndrome

🏥 Disease / Health Topic

Pain

Open on HERB 2.0 ↗

377

Clinical Trials

434

Meta-Analyses

PubMed References

📋 Sample Trials

NCT02201238

Pharmacokinetics Study Comparing Topical Diclofenac/Menthol Gels With Voltaren Gel and Oral Diclofenac Sodium

Completed · Phase 1

NCT02100670

A Multicenter Efficacy Study of a Diclofenac+Menthol Gel in Subjects With Ankle Sprain

Completed · Phase 3

NCT02169154

A Safety Study to Investigate the Skin Irritancy Potential of Diclofenac-Menthol Gel

Completed · Phase 1

📊 Sample Meta-Analyses

CRD42015016920

The effectiveness of moxibustion for treating knee osteoarthritis: a systematic review and meta-analyses

Knee osteoarthritis is a major cause of pain and functional limitation. Compleme

CRD42015016920

The effectiveness of moxibustion for treating knee osteoarthritis: a systematic review and meta-analyses

Knee osteoarthritis is a major cause of pain and functional limitation. Compleme

CRD42023392176

A network meta-analysis of effects of acupuncture and moxibustion on breast cancer-related lymphedema

Breast cancer is one of the most common malignant tumors in women, and the incid

📚 Sample References

None linked yet.

🏥 All Disease / Health Topic data fields for Pain

🏥 Names

Disease Name

Pain

Alias Names

Ache; Pain, Splitting; Suffering, Physical; Pain, Radiating; Pain, Crushing; Pain; Pain, Unspecified; Pain, Migratory; Pain, Burning

Topic Type

phenotype

🧬 Ontology Classifications

DisGeNET Type

phenotype

UMLS Type

Sign or Symptom

MeSH Class

Pathological Conditions, Signs and Symptoms

HPO Class

Constitutional symptom

🔗 External References

HERB DB

MeSH

ICD-10

HPO

DisGeNET

C0030193

🔍 Raw view — every non-empty column on this row (27 fields)

name

Pain

alias name

Ache; Pain, Splitting; Suffering, Physical; Pain, Radiating; Pain, Crushing; Pain; Pain, Unspecified; Pain, Migratory; Pain, Burning

topic type

phenotype

disgenet disease type

phenotype

umls disease type

Sign or Symptom

mesh disease class

Pathological Conditions, Signs and Symptoms

hpo disease class

Constitutional symptom

umls disease type id

T184

mesh disease class id

C23

hpo disease class id

HP:0025142

herb disease id

HBDIS002263

disgenet id

C0030193

mesh id

D010146

hpo id

HP:0012531

icd10 id

R52.9

🌿 Related Herbs

12 · shared evidence

Turmeric; Rhizome of Common Turmeric

Lemon Equivalent Plant: Citrus Limonia

Mountain Tobacco

⚗️ Related Ingredients

12 · shared evidence

2-methyl-1,4-naphthoquinone

4-pregnene-17α,20β,21-triol-3,11-dione

📜 Related Formulas

1 · contains this herb

Dajian Zhong Decoction; Da Jian Zhong Decoction

📋 Clinical Trials

12 · subject of clinical study

NCT02201238 Pharmacokinetics Study Comparing Topical Diclofenac/Menthol Gels With Voltaren G

→ Pain

NCT02100670 A Multicenter Efficacy Study of a Diclofenac+Menthol Gel in Subjects With Ankle

→ Pain

NCT02169154 A Safety Study to Investigate the Skin Irritancy Potential of Diclofenac-Menthol

→ Pain

NCT04677985 Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases

→ Pain, Acute|Muscle Soreness|Tendon Injuries

NCT05130957 The Effect of Clove Oil on Labor Pain

→ Labor Pain

NCT03723980 Role of Propolis Paste in Preventing Pain After Root Canal Treatment.

→ Pain, Postoperative

NCT04983524 Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrot

→ Post-Operative Pain, Chronic|Necrotic Pulp

NCT03670420 The Application of Honey on Perineal Sutures

→ Perineal Tear|Pain|Burns

NCT02187588 Study to Assess the Kinetic of the Analgesic Effect and Tolerability of Eschscho

→ Pain

NCT05206266 Bioenhancing Effects of Black Pepper With Turmeric on Pain Ratings

→ Pain

NCT04506411 Turmeric Efficacy for Mobility and Joint Function

→ Knee Discomfort|Joint Pain

NCT04946981 Recovery and Muscle Function After Supplementation With Turmeric

→ Muscle Soreness|Pain|Muscle Damage

📊 Meta-Analyses

12 · systematic review

CRD42015016920 The effectiveness of moxibustion for treating knee osteoarthritis: a systematic

→ Knee osteoarthritis is a major cause of pain and f

CRD42015016920 The effectiveness of moxibustion for treating knee osteoarthritis: a systematic

→ Knee osteoarthritis is a major cause of pain and f

CRD42023392176 A network meta-analysis of effects of acupuncture and moxibustion on breast canc

→ Breast cancer is one of the most common malignant

CRD42023392176 A network meta-analysis of effects of acupuncture and moxibustion on breast canc

→ Breast cancer is one of the most common malignant

CRD42022357108 Effect of moxibustion on inflammatory cytokines in patients with low back pain:

→ Low back pain (LBP) is a common problem worldwide.

CRD42022357108 Effect of moxibustion on inflammatory cytokines in patients with low back pain:

→ Low back pain (LBP) is a common problem worldwide.

CRD42020192572 Correction of Breech Presentation with Moxibustion and Acupuncture

→ Breech presentation is a common malposition in the

CRD42020192572 Correction of Breech Presentation with Moxibustion and Acupuncture

→ Breech presentation is a common malposition in the

CRD42022297018 Effect of Chinese herbal medicine for promoting circulation on dysmenorrhea: A s

→ Dysmenorrhea, one of the most common gynecological

CRD42022374372 Acupuncture, moxibustion, cupping, laser therapy and electroacupuncture in patie

→ Low back pain

CRD42019138266 Effects of moxibustion combined with Western medicine on diabetic peripheral neu

→ Diabetic peripheral neuropathy (DPN) is one of the

CRD42015019793 Systematic review and meta-analyses of effectiveness and safety of Brazilian med

→ Osteoarthritis affects 1% of world population and

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables