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Ingredient
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Gene Target
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Disease
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
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⚗️ Ingredient

Eriodictyol

Open on HERB 2.0 ↗
0
Clinical Trials
0
Meta-Analyses
4
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32158391
Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells via PI3K/Akt/NF-κB Signaling Pathway
Front Pharmacol · 2020
PMID 34785489
Eriodictyol protects skin cells from UVA irradiation-induced photodamage by inhibition of the MAPK signaling pathway
J Photochem Photobiol B · 2022
PMID 35093024
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation
Mol Med · 2022
⚗️ All Ingredient data fields for Eriodictyol
⚗️ Identity
Name
Eriodictyol
Aliases / Synonyms
552-58-9; Eriodictiol; (+)-Eriodictyol; Huazhongilexone; (S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one; UNII-Q520486B8Y; CHEBI:28412; (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
🧪 Chemistry
Molecular Weight
288.2550
LogP
2.2155
Drug-likeness
0.599
Oral Bioavailability
71.7930
H-Bond Acceptors
6
H-Bond Donors
4
Rotatable Bonds
1
🔬 Structures
Canonical SMILES
C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
Isomeric SMILES
C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
InChIKey
SBHXYTNGIZCORC-ZDUSSCGKSA-N
InChI
InChI=1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m0/s1
🔗 External References
HERB DB
HBIN025593 ↗
PubChem CID
440735 ↗
CAS Number
552-58-9 ↗
NPASS
NPC294852
HIT
C0050
SymMap
595
TCMID
7277
TCMSP
MOL005190
TCM-ID
4555
🔍 Raw view — every non-empty column on this row (36 fields)
name
Eriodictyol
common names
552-58-9; Eriodictiol; (+)-Eriodictyol; Huazhongilexone; (S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one; UNII-Q520486B8Y; CHEBI:28412; (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
herb ingredient id
HBIN025593
canonical smiles
C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
isomeric smiles
C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O
inchi
InChI=1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m0/s1
inchikey
SBHXYTNGIZCORC-ZDUSSCGKSA-N
mol wt
288.2550
num h acceptors
6
num h donors
4
mol logp
2.2155
num rotatable bonds
1
drug likeness
0.599
ob score
71.7930
cas id
552-58-9
symmap mol id
595
tcmid ingredient id
7277
tcmsp ingredient id
MOL005190
tcm id ingredient id
4555
pubchem cid
440735
npass id
NPC294852
hit id
C0050
tcmsp mol id
MOL005190
tcmsp molecule id
5190

🌿 Related Herbs

1 · contains this compound
Ephedra
Ma Huang

🧬 Gene / Protein Targets

9 · directly binds these targets
HMOX1
Gene HMOX1
NCOA2
Gene NCOA2
Prostaglandin G/H synthase 1
Prostaglandin G/H synthase 2
Heat shock protein HSP 90
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform
mRNA of PKA Catalytic Subunit C-alpha
Nuclear factor erythroid 2-related factor 2
NAD(P)H dehydrogenase [quinone] 1

🏥 Linked Health Topics

30 · diseases via target pathways
Cardiovascular disease, unspecified
disease
Chronic inflammatory diseases
disease
Alzheimer'S Disease
syndrome
Arthritis
syndrome
Renal Cell Carcinoma
disease
Carpal Tunnel Syndrome
syndrome
Endometriosis
syndrome
Inflammation
phenotype
Meningioma
disease
Myocardial Infarction
syndrome
Peutz-Jeghers Syndrome
syndrome
Malignant Mesothelioma
disease
Colorectal cancer
disease
Cancer, unspecific
disease
Lung Cancer
disease
Osteoarthritis
disease
Breast cancer
disease
Prostate cancer
disease
Rheumatoid arthritis, unspecified
disease
Analgesics
disease
Stroke
disease
Inflammatory diseases
disease
Bladder cancer
disease
Abdominal aortic aneurysm
disease
Adenomatous polyposis
disease
Carcinoma in situ, unspecified
disease
Dysmenorrhea, unspecified
disease
Genitourinary tumors
disease
Gestational hypertension
disease
Oropharyngeal squamous cell carcinoma
disease

📚 PubMed References

4 · cited research
PMID 32158391 Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma C
Front Pharmacol
PMID 34785489 Eriodictyol protects skin cells from UVA irradiation-induced photodamage by inhi
J Photochem Photobiol B
PMID 35093024 Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferr
Mol Med
PMID 35184647 Eriodictyol suppresses the malignant progression of colorectal cancer by downreg
Bioengineered
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables