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Plus 6,743 TCM formulas connecting herbs together
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⚗️ Ingredient

Gamma-tocopherol

Open on HERB 2.0 ↗
2
Clinical Trials
0
Meta-Analyses
5
PubMed References
Top Conditions Studied with Gamma-tocopherol
Endothelial Dysfunction 1 Allergic|Asthmatic|Allergy|Asthma 1
📋 Sample Trials
NCT00836368
In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics
Completed · Phase 1
NCT01314443
Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function
Completed · Phase 1|Phase 2
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 29662196
Tocopherols inhibit esophageal carcinogenesis through attenuating NF-κB activation and CXCR3-mediated inflammation
Oncogene · 2018
PMID 24333275
Supplementation with γ-tocopherol attenuates endotoxin-induced airway neutrophil and mucous cell responses in rats
Free Radic Biol Med · 2014
PMID 24075893
γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation
Free Radic Biol Med · 2013
⚗️ All Ingredient data fields for Gamma-tocopherol
⚗️ Identity
Name
Gamma-tocopherol
Aliases / Synonyms
54-28-4; D-gamma-Tocopherol; (+)-gamma-Tocopherol; 7,8-Dimethyltocol; o-Xylotocopherol; Gamma tocopherol; (R,R,R)-gamma-Tocopherol; .gamma.-Tocopherol; Rrr-.gamma.-tocopherol
🧪 Chemistry
Molecular Weight
416.6900
LogP
8.5318
Drug-likeness
0.37
Oral Bioavailability
15.6210
H-Bond Acceptors
2
H-Bond Donors
1
Rotatable Bonds
12
🔬 Structures
Canonical SMILES
CC1=C(C=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)O
Isomeric SMILES
CC1=C(C=C2CC[C@@](OC2=C1C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O
InChIKey
QUEDXNHFTDJVIY-DQCZWYHMSA-N
InChI
InChI=1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1
🔗 External References
HERB DB
HBIN027166 ↗
PubChem CID
92729 ↗
CAS Number
54-28-4 ↗
NPASS
NPC48623
HIT
C0629
TCMID
32215; 21398
TCMSP
MOL002373
TCM-ID
22690
🔍 Raw view — every non-empty column on this row (33 fields)
name
Gamma-tocopherol
common names
54-28-4; D-gamma-Tocopherol; (+)-gamma-Tocopherol; 7,8-Dimethyltocol; o-Xylotocopherol; Gamma tocopherol; (R,R,R)-gamma-Tocopherol; .gamma.-Tocopherol; Rrr-.gamma.-tocopherol
herb ingredient id
HBIN027166
canonical smiles
CC1=C(C=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)O
isomeric smiles
CC1=C(C=C2CC[C@@](OC2=C1C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O
inchi
InChI=1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1
inchikey
QUEDXNHFTDJVIY-DQCZWYHMSA-N
mol wt
416.6900
num h acceptors
2
num h donors
1
mol logp
8.5318
num rotatable bonds
12
drug likeness
0.37
ob score
15.6210
cas id
54-28-4
tcmid ingredient id
32215; 21398
tcmsp ingredient id
MOL002373
tcm id ingredient id
22690
pubchem cid
92729
npass id
NPC48623
hit id
C0629

🏥 Linked Health Topics

1 · studied for these conditions (text bridge)
Endothelial Dysfunction
phenotype

📋 Clinical Trials

2 · subject of clinical study
NCT00836368 In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Su
→ Allergic|Asthmatic|Allergy|Asthma
NCT01314443 Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Fun
→ Endothelial Dysfunction

📚 PubMed References

5 · cited research
PMID 29662196 Tocopherols inhibit esophageal carcinogenesis through attenuating NF-κB activati
Oncogene
PMID 24333275 Supplementation with γ-tocopherol attenuates endotoxin-induced airway neutrophil
Free Radic Biol Med
PMID 24075893 γ-Tocopherol-rich supplementation additively improves vascular endothelial funct
Free Radic Biol Med
PMID 23512990 Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLP
Sci Signal
PMID 34896589 Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant
Free Radic Biol Med
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables