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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Hemin

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Hemin

Healthy Volunteers 1 Acute Intermittent Porphyria|Hereditary Coproporphyria|Varie 1 Post-ERCP Acute Pancreatitis 1

📋 Sample Trials

NCT00882804

Hemin in Healthy Subjects

Completed · Phase 1

NCT02922413

Panhematin for Prevention of Acute Attacks of Porphyria

Terminated · Phase 2

NCT01855841

Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis

Completed · Phase 2

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

PMID 31843526

Hemin treatment protects neonatal rats from sevoflurane-induced neurotoxicity via the phosphoinositide 3-kinase/Akt pathway

Life Sci · 2020

PMID 32726649

Catalytic nanographene oxide with hemin for enhanced photodynamic therapy

J Control Release · 2020

PMID 33187129

Hemin Prevents Increased Glycolysis in Macrophages upon Activation: Protection by Microbiota-Derived Metabolites of Polyphenols

Antioxidants (Basel) · 2020

⚗️ All Ingredient data fields for Hemin

⚗️ Identity

Name

Hemin

Aliases / Synonyms

Panhematin; Chlorohemin; 16009-13-5; hemin chloride; Ferriprotoporphyrin chloride; HEMIN [VANDF]; HEMIN [JAN]; HEMIN [WHO-DD]; HEMIN [MI]

🧪 Chemistry

Molecular Weight

651.9520

LogP

3.4591

Drug-likeness

0.355

Oral Bioavailability

8.2940

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]

Isomeric SMILES

CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]

InChIKey

BTIJJDXEELBZFS-UHFFFAOYSA-K

InChI

InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3

🔗 External References

HERB DB

HBIN029001 ↗

PubChem CID

455658 ↗

CAS Number

16009-13-5 ↗

SymMap

11310

TCMID

9344

TCMSP

MOL010250

TCM-ID

13007

🔍 Raw view — every non-empty column on this row (32 fields)

name

Hemin

common names

Panhematin; Chlorohemin; 16009-13-5; hemin chloride; Ferriprotoporphyrin chloride; HEMIN [VANDF]; HEMIN [JAN]; HEMIN [WHO-DD]; HEMIN [MI]

herb ingredient id

HBIN029001

canonical smiles

CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]

isomeric smiles

CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]

inchi

inchikey

BTIJJDXEELBZFS-UHFFFAOYSA-K

mol wt

651.9520

num h acceptors

num h donors

mol logp

3.4591

num rotatable bonds

drug likeness

0.355

ob score

8.2940

cas id

16009-13-5

symmap mol id

11310

tcmid ingredient id

9344

tcmsp ingredient id

MOL010250

tcm id ingredient id

13007

pubchem cid

455658

📋 Clinical Trials

3 · subject of clinical study

NCT00882804 Hemin in Healthy Subjects

→ Healthy Volunteers

NCT02922413 Panhematin for Prevention of Acute Attacks of Porphyria

→ Acute Intermittent Porphyria|Hereditary Coproporph

NCT01855841 Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acut

→ Post-ERCP Acute Pancreatitis

📚 PubMed References

6 · cited research

PMID 31843526 Hemin treatment protects neonatal rats from sevoflurane-induced neurotoxicity vi

Life Sci

PMID 32726649 Catalytic nanographene oxide with hemin for enhanced photodynamic therapy

J Control Release

PMID 33187129 Hemin Prevents Increased Glycolysis in Macrophages upon Activation: Protection b

Antioxidants (Basel)

PMID 35218766 Administration of hemin ameliorates ovarian ischemia reperfusion injury via modu

Life Sci

PMID 36230727 High Hemin Concentration Induces Escape from Senescence of Normoxic and Hypoxic

Cancers (Basel)

PMID 36525776 Hemin protects UVB-induced skin damage through inhibiting keratinocytes apoptosi

J Photochem Photobiol B

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables