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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿
Herb
6,826
→
⚗️
Ingredient
44,598
→
🧬
Gene Target
15,695
→
🏥
Disease
30,467
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins
⚗️ Ingredient

Herbacetin

Open on HERB 2.0 ↗
0
Clinical Trials
0
Meta-Analyses
0
PubMed References
⚗️ All Ingredient data fields for Herbacetin
⚗️ Identity
Name
Herbacetin
Aliases / Synonyms
527-95-7; 8-Hydroxykaempferol; Isoarticulatidin; 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one; 3,4',5,7,8-Pentahydroxyflavone; 3,5,7,8,4'-Pentahydroxyflavone; 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 736854V2KE; Flavone, 3,4',5,7,8-pentahydroxy-
🧪 Chemistry
Molecular Weight
302.2380
LogP
1.9880
Drug-likeness
0.343
Oral Bioavailability
36.0740
H-Bond Acceptors
7
H-Bond Donors
5
Rotatable Bonds
1
🔬 Structures
Canonical SMILES
C1=CC(=CC=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O
Isomeric SMILES
C1=CC(=CC=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O
InChIKey
ZDOTZEDNGNPOEW-UHFFFAOYSA-N
InChI
InChI=1S/C15H10O7/c16-7-3-1-6(2-4-7)14-13(21)12(20)10-8(17)5-9(18)11(19)15(10)22-14/h1-5,16-19,21H
🔗 External References
HERB DB
HBIN029135 ↗
PubChem CID
5280544 ↗
CAS Number
527-95-7 ↗
NPASS
NPC225731
HIT
C0495
TCMID
9420
TCMSP
MOL002823
TCM-ID
3776
🔍 Raw view — every non-empty column on this row (35 fields)
name
Herbacetin
common names
527-95-7; 8-Hydroxykaempferol; Isoarticulatidin; 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one; 3,4',5,7,8-Pentahydroxyflavone; 3,5,7,8,4'-Pentahydroxyflavone; 3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 736854V2KE; Flavone, 3,4',5,7,8-pentahydroxy-
herb ingredient id
HBIN029135
canonical smiles
C1=CC(=CC=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O
isomeric smiles
C1=CC(=CC=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O
inchi
InChI=1S/C15H10O7/c16-7-3-1-6(2-4-7)14-13(21)12(20)10-8(17)5-9(18)11(19)15(10)22-14/h1-5,16-19,21H
inchikey
ZDOTZEDNGNPOEW-UHFFFAOYSA-N
mol wt
302.2380
num h acceptors
7
num h donors
5
mol logp
1.9880
num rotatable bonds
1
drug likeness
0.343
ob score
36.0740
cas id
527-95-7
tcmid ingredient id
9420
tcmsp ingredient id
MOL002823
tcm id ingredient id
3776
pubchem cid
5280544
npass id
NPC225731
hit id
C0495
tcmsp mol id
MOL002823
tcmsp molecule id
2823

🌿 Related Herbs

1 · contains this compound
Ephedra
Ma Huang

🧬 Gene / Protein Targets

14 · directly binds these targets
AR
Gene AR
PPARG
Gene PPARG
Prostaglandin G/H synthase 1
Prostaglandin G/H synthase 2
Heat shock protein HSP 90
Dipeptidyl peptidase IV
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform
Thrombin
Gamma-aminobutyric-acid receptor alpha-2 subunit
Acetylcholinesterase
Muscarinic acetylcholine receptor M2
Gamma-aminobutyric acid receptor subunit alpha-1
Ig gamma-1 chain C region
Trypsin-1

🏥 Linked Health Topics

30 · diseases via target pathways
Hypospadias 1, X-Linked
syndrome
Prostate cancer
disease
Spinal and bulbar muscular atrophy
disease
XY disorders of sex development (Other)
disease
XY disorders of sex development (Disorders in androgen synthesis or action)
disease
Spinal and bulbar muscular atrophy of Kennedy
disease
Androgen insensitivity
disease
Asthma
syndrome
Atherosclerosis
syndrome
Autoimmune Diseases
group
Renal Cell Carcinoma
disease
Ulcerative Colitis
syndrome
Diabetes Mellitus
group
Inflammation
phenotype
Insulin Resistance
phenotype
Multiple Sclerosis
syndrome
Obesity
syndrome
Psoriasis
syndrome
Pancreatic Cancer
disease
Crohns's Disease, unspecified
disease
Atopic Dermatitis
disease
Chronic inflammatory diseases
disease
Adrenocorticotrophic hormone-secreting pituitary tumors
disease
Bladder cancer
disease
Inflammatory Bowel Disease
disease
Ischemic heart disease
disease
Testicular cancer
disease
Thyroid follicular carcinoma
disease
Cardiovascular disease, unspecified
disease
Alzheimer'S Disease
syndrome
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables