Relationship Graph Explorer
Follow the connections
Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
🌿
Herb
6,826
→
⚗️
Ingredient
44,598
→
🧬
Gene Target
15,695
→
🏥
Disease
30,467
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Ibogain
1
Clinical Trials
3
Meta-Analyses
0
PubMed References
Top Conditions Studied with Ibogain
📋 Sample Trials
NCT04003948
Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification
Unknown · Phase 2
📊 Sample Meta-Analyses
CRD42021287034
Ibogaine and Noribogaine in Substance Use Disorder: a systematic review of the literature
Ibogaine. Noribogaine. Substance Use Disorder (SUD). Addiction. Craving.
CRD42020201481
The adverse effects of ibogaine: A systematic review of literature (2015-2020) with special attention to drug-drug interactions
The aim of this manuscript is to perform a systematic review of literature in or
CRD42021242392
A systematic literature review of clinical trials and therapeutic applications of iboga, ibogaine and noribogaine
Mental Health
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Ibogain
⚗️ Identity
Name
Ibogain
Aliases / Synonyms
IBOGAINE; 12-Methoxyibogamine; Endabuse; (-)-Ibogaine; 83-74-9; (5beta)-12-methoxyibogamine; Ibogamine, 12-methoxy-; EINECS 201-498-4; NSC 249764
🧪 Chemistry
Molecular Weight
310.4410
LogP
3.9366
Drug-likeness
0.91
Oral Bioavailability
50.5210
H-Bond Acceptors
2
H-Bond Donors
1
Rotatable Bonds
2
🔬 Structures
Canonical SMILES
CCC1CC2CC3C1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC
Isomeric SMILES
CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC
InChIKey
HSIBGVUMFOSJPD-CFDPKNGZSA-N
InChI
InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1
🔗 External References
🔍 Raw view — every non-empty column on this row (30 fields)
name
Ibogain
common names
IBOGAINE; 12-Methoxyibogamine; Endabuse; (-)-Ibogaine; 83-74-9; (5beta)-12-methoxyibogamine; Ibogamine, 12-methoxy-; EINECS 201-498-4; NSC 249764
herb ingredient id
HBIN029910
canonical smiles
CCC1CC2CC3C1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC
isomeric smiles
CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC
inchi
InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1
inchikey
HSIBGVUMFOSJPD-CFDPKNGZSA-N
mol wt
310.4410
num h acceptors
2
num h donors
1
mol logp
3.9366
num rotatable bonds
2
drug likeness
0.91
ob score
50.5210
cas id
17378-46-0
symmap mol id
3103
tcmsp ingredient id
MOL000529
pubchem cid
197060
📋 Clinical Trials
1 · subject of clinical studyNCT04003948 Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxi
→ Drug Dependence|Drug Use Disorders|Opioid Dependen
📊 Meta-Analyses
3 · systematic reviewCRD42021287034 Ibogaine and Noribogaine in Substance Use Disorder: a systematic review of the l
→ Ibogaine. Noribogaine. Substance Use Disorder (SUD
CRD42020201481 The adverse effects of ibogaine: A systematic review of literature (2015-2020) w
→ The aim of this manuscript is to perform a systema
CRD42021242392 A systematic literature review of clinical trials and therapeutic applications o
→ Mental Health
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables