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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
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Ingredient
44,595
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Gene Target
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→
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Disease
30,170
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
🏥 Disease / Health Topic
Septic Shock
46
Clinical Trials
86
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT01284452
Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Completed
NCT02114710
Effects of Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock
Completed · Phase 3
NCT02266589
Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock
Completed · Phase 3
📊 Sample Meta-Analyses
CRD42017062198
Effects of hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock
We will consider adults with septic shock as defined in individual trials.
CRD42018090792
The effects of low dose hydrocortisone in patients with sepsis or septic shock
Patients with sepsis or septic shock.
CRD42018100112
Impact of hydrocortisone in sepsis and septic shock on mortality. A protocol of literature review and meta-analysis
The included conditions are sepsis or septic shock as defined by the Third Inter
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Septic Shock
🏥 Names
Disease Name
Septic Shock
Alias Names
Shock, Septic; Shock, Endotoxic; Septic Shock; Toxic Shock Syndrome
Topic Type
phenotype
🧬 Ontology Classifications
DisGeNET Type
phenotype
UMLS Type
Pathologic Function
MeSH Class
Infections; Pathological Conditions, Signs and Symptoms
DO Class
disease by infectious agent
🔗 External References
🔍 Raw view — every non-empty column on this row (26 fields)
name
Septic Shock
alias name
Shock, Septic; Shock, Endotoxic; Septic Shock; Toxic Shock Syndrome
topic type
phenotype
disgenet disease type
phenotype
umls disease type
Pathologic Function
mesh disease class
Infections; Pathological Conditions, Signs and Symptoms
do disease class
disease by infectious agent
umls disease type id
T046
mesh disease class id
C01; C23
do disease class id
DOID:0050117
herb disease id
HBDIS002740
disgenet id
C0036983
mesh id
D012772
do id
14115
⚗️ Related Ingredients
9 · shared evidence📋 Clinical Trials
12 · subject of clinical studyNCT01284452 Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients W
→ Septic Shock|Severe Sepsis|Acute Lung Injury|Acute
NCT02114710 Effects of Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients
→ Coagulation Dysfunction in Septic Shock|Hemodynami
NCT02266589 Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septi
→ Septic Shock|Sepsis
NCT02580240 Initiation of Hydrocortisone for the Treatment of Septic Shock
→ Septic Shock
NCT02768740 Hydrocortisone 50 mg Every 6 Hours Compared to Hydrocortisone 300 mg Per Day in
→ Septic Shock
NCT03401398 Stress Hydrocortisone In Pediatric Septic Shock
→ Septic Shock
NCT03872011 Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
→ Septic Shock
NCT03872011 Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
→ Septic Shock
NCT03872011 Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
→ Septic Shock
NCT04197115 Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
→ Sepsis|Septic Shock
NCT04197115 Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
→ Sepsis|Septic Shock
NCT04492280 Evaluation of the Role of Hydrocortisone Either Alone or Combined With Fludrocor
→ Septic Shock
📊 Meta-Analyses
12 · systematic reviewCRD42017062198 Effects of hydrocortisone and hydrocortisone plus fludrocortisone in adults with
→ We will consider adults with septic shock as defin
CRD42018090792 The effects of low dose hydrocortisone in patients with sepsis or septic shock
→ Patients with sepsis or septic shock.
CRD42018100112 Impact of hydrocortisone in sepsis and septic shock on mortality. A protocol of
→ The included conditions are sepsis or septic shock
CRD42019139069 Fludrocortisone with hydrocortisone for adult patients with septic shock
→ Septic shock
CRD42019139343 Effect of hydrocortisone for adults patients with septic shock unresponsive to i
→ Septic shock.
CRD42020170648 Effect of combined vitamin C, hydrocortisone and thiamine for patients with sept
→ Nowadays, the mortality rate of septic shock remai
CRD42020170648 Effect of combined vitamin C, hydrocortisone and thiamine for patients with sept
→ Nowadays, the mortality rate of septic shock remai
CRD42020170648 Effect of combined vitamin C, hydrocortisone and thiamine for patients with sept
→ Nowadays, the mortality rate of septic shock remai
CRD42020203166 Hydrocortisone, ascorbic acid and thiamine for sepsis and septic shock: a meta-a
→ The effect of treatment with hydrocortisone, ascor
CRD42020203166 Hydrocortisone, ascorbic acid and thiamine for sepsis and septic shock: a meta-a
→ The effect of treatment with hydrocortisone, ascor
CRD42020203166 Hydrocortisone, ascorbic acid and thiamine for sepsis and septic shock: a meta-a
→ The effect of treatment with hydrocortisone, ascor
CRD42020206950 Combination therapy of thiamine and vitamin C in treating patients with sepsis o
→ Sepsis is a common yet complex disorder that remai
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
empty — needs
HERB_herb_ingredientimport - Ingredient ↔ Target:
empty — needs
HERB_ingredient_targetimport - Target ↔ Disease:
empty — needs
HERB_target_diseaseimport - Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables