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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
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⚗️ Ingredient

Isoquercitrin

Open on HERB 2.0 ↗
6
Clinical Trials
0
Meta-Analyses
2
PubMed References
Top Conditions Studied with Isoquercitrin
Healthy 1 Chronic Kidney Disease 1 Thromboembolism of Vein VTE in Colorectal Cancer|Thromboembo 1 Sickle Cell Disease 1 SARS-CoV 2|COVID-19|Coronavirus Disease 2019 1 Overweight|Obese 1
📋 Sample Trials
NCT02195232
Cancer Associated Thrombosis and Isoquercetin (CATIQ)
Completed · Phase 2|Phase 3
NCT02552888
Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial
Completed · Phase 2
NCT04514510
Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease
Completed · Phase 2
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32692981
Cellular target of isoquercetin from Passiflora ligularis Juss for glucose uptake in rat soleus muscle
Chem Biol Interact · 2020
PMID 34626776
Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway
J Ethnopharmacol · 2021
⚗️ All Ingredient data fields for Isoquercitrin
⚗️ Identity
Name
Isoquercitrin
Aliases / Synonyms
Isoquercetin; 482-35-9; Hirsutrin; Quercetin 3-glucoside; 3-Glucosylquercetin; Quercetin 3-o-glucopyranoside; Quercetin 3-D-glucoside; Quercetol 3-monoglucoside; Quercetin 3-O-glucoside
🧪 Chemistry
Molecular Weight
464.3790
LogP
-0.5389
Drug-likeness
0.229
H-Bond Acceptors
12
H-Bond Donors
8
Rotatable Bonds
4
🔬 Structures
Canonical SMILES
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O
Isomeric SMILES
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O
InChIKey
OVSQVDMCBVZWGM-QSOFNFLRSA-N
InChI
InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1
🔗 External References
HERB DB
HBIN031102 ↗
PubChem CID
5280804 ↗
CAS Number
21637-25-2 ↗
NPASS
NPC179950
HIT
C0156
TCMID
11639
TCMSP
MOL002051
TCM-ID
3357
🔍 Raw view — every non-empty column on this row (32 fields)
name
Isoquercitrin
common names
Isoquercetin; 482-35-9; Hirsutrin; Quercetin 3-glucoside; 3-Glucosylquercetin; Quercetin 3-o-glucopyranoside; Quercetin 3-D-glucoside; Quercetol 3-monoglucoside; Quercetin 3-O-glucoside
herb ingredient id
HBIN031102
canonical smiles
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O
isomeric smiles
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O
inchi
InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1
inchikey
OVSQVDMCBVZWGM-QSOFNFLRSA-N
mol wt
464.3790
num h acceptors
12
num h donors
8
mol logp
-0.5389
num rotatable bonds
4
drug likeness
0.229
cas id
21637-25-2
tcmid ingredient id
11639
tcmsp ingredient id
MOL002051
tcm id ingredient id
3357
pubchem cid
5280804
npass id
NPC179950
hit id
C0156

📋 Clinical Trials

6 · subject of clinical study
NCT02195232 Cancer Associated Thrombosis and Isoquercetin (CATIQ)
→ Thromboembolism of Vein VTE in Colorectal Cancer|T
NCT02552888 Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial
→ Chronic Kidney Disease
NCT04514510 Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects
→ Sickle Cell Disease
NCT04622865 Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Pa
→ SARS-CoV 2|COVID-19|Coronavirus Disease 2019
NCT01722669 Quercetin PK/PD Study in Healthy Adults and Patients With Hypercoagulable States
→ Healthy
NCT02818699 Body Fat Reducing Effect and Safety of Enzymatically Modified Isoquercitrin in O
→ Overweight|Obese

📚 PubMed References

2 · cited research
PMID 32692981 Cellular target of isoquercetin from Passiflora ligularis Juss for glucose uptak
Chem Biol Interact
PMID 34626776 Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/
J Ethnopharmacol
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables