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Relationship Graph Explorer

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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿
Herb
6,826
→
⚗️
Ingredient
44,595
→
🧬
Gene Target
15,505
→
🏥
Disease
30,170
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Abetalipoproteinemia Abortion, Habitual Agenesis Acanthamoeba Keratitis Acanthosis Nigricans Achondrogenesis Achondroplasia Acne Vulgaris Acne Keloid Apert Syndrome
🏥 Disease / Health Topic

Tobacco Dependence

Open on HERB 2.0 ↗
27
Clinical Trials
2
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT01018394
Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
Completed · Phase 2|Phase 3
NCT01084707
Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product.
Completed
NCT01113424
Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum
Completed
📊 Sample Meta-Analyses
CRD42020158832
A systematic review of alternative electronic nicotine delivery systems (ANDS)-based interventions in reducing tobacco smoking in marginalised populations
Tobacco dependence
CRD42022383757
Structural and Functional brain aberrations correlated with Pharmacotherapy in nicotine addicts - A meta-analysis of longitudinal studies
Tobacco addiction according to ICD/DSM diagnostic criteria, tobacco dependence r
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Tobacco Dependence
🏥 Names
Disease Name
Tobacco Dependence
Alias Names
Nicotine Dependence; Mental And Behavioural Disorders Due To Use of Tobacco, Dependence Syndrome; Tobacco Dependence; Nicotine Use Disorder
Topic Type
disease
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Mental or Behavioral Dysfunction
MeSH Class
Mental Disorders; Chemically-Induced Disorders
🔗 External References
HERB DB
HBDIS002960 ↗
MeSH
D014029 ↗
ICD-10
F17.2 ↗
DisGeNET
C0040332
🔍 Raw view — every non-empty column on this row (24 fields)
name
Tobacco Dependence
alias name
Nicotine Dependence; Mental And Behavioural Disorders Due To Use of Tobacco, Dependence Syndrome; Tobacco Dependence; Nicotine Use Disorder
topic type
disease
disgenet disease type
disease
umls disease type
Mental or Behavioral Dysfunction
mesh disease class
Mental Disorders; Chemically-Induced Disorders
umls disease type id
T048
mesh disease class id
F03; C25
herb disease id
HBDIS002960
disgenet id
C0040332
mesh id
D014029
icd10 id
F17.2

⚗️ Related Ingredients

2 · shared evidence
Cannabidiol
(?)-nicotine

📋 Clinical Trials

12 · subject of clinical study
NCT01018394 Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
→ Tobacco Dependence
NCT01084707 Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Pro
→ Tobacco Dependence
NCT01113424 Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum
→ Tobacco Dependence
NCT01234792 Single-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Produ
→ Tobacco Dependence
NCT01234896 Single-dose Nicotine Pharmacokinetics With Four Oral Nicotine Replacement Produc
→ Tobacco Dependence
NCT01321931 Multiple-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Pro
→ Tobacco Dependence
NCT01368016 Nicotine Pharmacodynamics With a New Oral Nicotine Replacement Therapy and Nicot
→ Tobacco Dependence
NCT01440985 A Study on the Effects of Two Nicotine Replacement Products on Tooth Staining
→ Tobacco Dependence
NCT01681875 Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarett
→ Tobacco Dependence
NCT01928719 Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status
→ Tobacco Dependence
NCT01928758 Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders
→ Tobacco Dependence
NCT02355665 Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Thera
→ Tobacco Dependence

📊 Meta-Analyses

2 · systematic review
CRD42020158832 A systematic review of alternative electronic nicotine delivery systems (ANDS)-b
→ Tobacco dependence
CRD42022383757 Structural and Functional brain aberrations correlated with Pharmacotherapy in n
→ Tobacco addiction according to ICD/DSM diagnostic
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables