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Evidence
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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
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⚗️ Ingredient

Ldp

Open on HERB 2.0 ↗
20
Clinical Trials
2
Meta-Analyses
0
PubMed References
Top Conditions Studied with Ldp
Kidney Transplantation|ESRD 1 Anesthesia|Infant|Congenital Heart Disease|Hemodynamic Insta 1 Intra Operative Fluid Management 1 Adiposity|Weight Loss 1 Probable transitional circulatory shock (as defined by the a 1 Hypotension 1 Critically ill patients. Mortality and adverse events. 1 Hyperglycemia|Sepsis 1 Shock Hypovolemic|Shock, Septic|Blood Transfusion|Adrenaline 1 Heart Failure, Diastolic 1 Shock 1 Health 1
📋 Sample Trials
NCT02201121
Influences of Phenylephrine, Dopamine and Ephedrine on Stroke Volume Variation and Pulse Pressure Variation
Completed
NCT00115115
Donor Dopamine and Initial Graft Function
Completed · Phase 4
NCT00314704
Dopamine and Norepinephrine in Shock Patients
Completed · Phase 3
📊 Sample Meta-Analyses
CRD42016042867
Dopamine for cardiac dysfunction in critically ill adult patients: a systematic review with meta-analysis and trial sequential analysis
Critically ill patients. Mortality and adverse events.
CRD42023446535
Treatment of preterm neonates with probable transitional circulatory shock: A systematic review, network meta-analysis and clinical practice guidelines.
Probable transitional circulatory shock (as defined by the author)
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Ldp
⚗️ Identity
Name
Ldp
Aliases / Synonyms
dopamine; 4-(2-Aminoethyl)benzene-1,2-diol; 51-61-6; 3-Hydroxytyramine; Oxytyramine; Hydroxytyramin; Dopamin; 3,4-dihydroxyphenethylamine; hydroxytyramine; intropin
🧪 Chemistry
Molecular Weight
153.1810
LogP
0.5990
Drug-likeness
0.545
Oral Bioavailability
74.3990
H-Bond Acceptors
3
H-Bond Donors
3
Rotatable Bonds
2
🔬 Structures
Canonical SMILES
C1=CC(=C(C=C1CCN)O)O
Isomeric SMILES
C1=CC(=C(C=C1CCN)O)O
InChIKey
VYFYYTLLBUKUHU-UHFFFAOYSA-N
InChI
InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
🔗 External References
HERB DB
HBIN032819 ↗
PubChem CID
681 ↗
CAS Number
50444-17-2 ↗
NPASS
NPC146422
HIT
C0034
SymMap
7198
TCMSP
MOL005442
🔍 Raw view — every non-empty column on this row (32 fields)
name
Ldp
common names
dopamine; 4-(2-Aminoethyl)benzene-1,2-diol; 51-61-6; 3-Hydroxytyramine; Oxytyramine; Hydroxytyramin; Dopamin; 3,4-dihydroxyphenethylamine; hydroxytyramine; intropin
herb ingredient id
HBIN032819
canonical smiles
C1=CC(=C(C=C1CCN)O)O
isomeric smiles
C1=CC(=C(C=C1CCN)O)O
inchi
InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
inchikey
VYFYYTLLBUKUHU-UHFFFAOYSA-N
mol wt
153.1810
num h acceptors
3
num h donors
3
mol logp
0.5990
num rotatable bonds
2
drug likeness
0.545
ob score
74.3990
cas id
50444-17-2
symmap mol id
7198
tcmsp ingredient id
MOL005442
pubchem cid
681
npass id
NPC146422
hit id
C0034

🏥 Linked Health Topics

7 · studied for these conditions (text bridge)
Hypotension
phenotype
Parkinson Disease
syndrome
Prolactinoma
disease
Shock
phenotype
Septic Shock
phenotype
Chronic Pain
phenotype
Heart Failure, Diastolic
syndrome

📋 Clinical Trials

12 · subject of clinical study
NCT02201121 Influences of Phenylephrine, Dopamine and Ephedrine on Stroke Volume Variation a
→ Circulation|Drug Dose|Calculated SAP
NCT00115115 Donor Dopamine and Initial Graft Function
→ Kidney Transplantation|ESRD
NCT00314704 Dopamine and Norepinephrine in Shock Patients
→ Shock
NCT00604019 Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic
→ Septic Shock
NCT01318278 Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low
→ Hypotension
NCT01901809 Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction
→ Heart Failure, Diastolic
NCT02053935 Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects
→ Hyperglycemia|Sepsis
NCT02241083 The Effect of Norepinephrine and Dopamine on Radial Forearm Free Flap Tissue Oxy
→ Head and Neck Cancer
NCT02965963 The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During
→ Health
NCT03780686 Dopamine and Norepinephrine Infusion With Restricted Hydration
→ Renal Function Test, Urine Output, Lactate Level
NCT04525495 Dopamine in Neonate
→ Neonates and Preterm Infants
NCT04753008 Respiratory Effects of Dopamine in the Perioperative Care
→ Dopamine|Bronchodilation|Heart|Surgery|Functional

📊 Meta-Analyses

2 · systematic review
CRD42016042867 Dopamine for cardiac dysfunction in critically ill adult patients: a systematic
→ Critically ill patients. Mortality and adverse ev
CRD42023446535 Treatment of preterm neonates with probable transitional circulatory shock: A sy
→ Probable transitional circulatory shock (as define
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables