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Herb
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Ingredient
44,598
→
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Gene Target
15,695
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Leucinum
2
Clinical Trials
7
Meta-Analyses
0
PubMed References
Top Conditions Studied with Leucinum
Hypertrophy|Strength Training Adaptations|Weight-Bearing Str 1
Healthy 1
The European Working Group on Sarcopenia in Older People (EW 1
Sarcopenia is a state of age-related progressive loss of mus 1
Older adults are at a greater risk of developing sarcopenia 1
Nutritional metabolism relating to muscle health has signifi 1
Leucine has been thought to augment adaptations to strength 1
It has been suggested that the leucine supplementation and i 1
Anthropometric outcomes: body weight, BMI, lean body mass, f 1
📋 Sample Trials
NCT05720390
Effects of Intragastric Quinine, Alone or Combined With L-leucine, on Postprandial Glycaemic Control
Recruiting
NCT06121869
Dileucine and Resistance Training Adaptations
Completed
📊 Sample Meta-Analyses
CRD42022342953
Leucine Enriched Whey Protein on Measures of Sarcopenia
Sarcopenia is a state of age-related progressive loss of muscle mass and functio
CRD42022357780
Effects of Leucine-enriched amino acid/whey protein supplement and exercise intervention on Sarcopenia in older adults: a systematic review and meta-analysis of randomized controlled trials
The European Working Group on Sarcopenia in Older People (EWGSOP) defines sarcop
CRD42013004477
Leucine supplementation and body composition in the elderly: a systematic review and meta-analysis
Anthropometric outcomes: body weight, BMI, lean body mass, fat mass Cardiovascul
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Leucinum
⚗️ Identity
Name
Leucinum
Aliases / Synonyms
L-leucine; leucine; 61-90-5; (S)-Leucine; H-Leu-OH; (S)-2-Amino-4-methylpentanoic acid; (2S)-2-amino-4-methylpentanoic acid; Leucin; (S)-(+)-Leucine; leu
🧪 Chemistry
Molecular Weight
131.1750
LogP
0.4444
Drug-likeness
0.584
Oral Bioavailability
72.9190
H-Bond Acceptors
2
H-Bond Donors
2
Rotatable Bonds
3
🔬 Structures
Canonical SMILES
CC(C)CC(C(=O)O)N
Isomeric SMILES
CC(C)C[C@@H](C(=O)O)N
InChIKey
ROHFNLRQFUQHCH-YFKPBYRVSA-N
InChI
InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
🔗 External References
🔍 Raw view — every non-empty column on this row (30 fields)
name
Leucinum
common names
L-leucine; leucine; 61-90-5; (S)-Leucine; H-Leu-OH; (S)-2-Amino-4-methylpentanoic acid; (2S)-2-amino-4-methylpentanoic acid; Leucin; (S)-(+)-Leucine; leu
herb ingredient id
HBIN032992
canonical smiles
CC(C)CC(C(=O)O)N
isomeric smiles
CC(C)C[C@@H](C(=O)O)N
inchi
InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
inchikey
ROHFNLRQFUQHCH-YFKPBYRVSA-N
mol wt
131.1750
num h acceptors
2
num h donors
2
mol logp
0.4444
num rotatable bonds
3
drug likeness
0.584
ob score
72.9190
cas id
71000-80-1
symmap mol id
7203
tcmsp ingredient id
MOL005448
pubchem cid
6106
📋 Clinical Trials
2 · subject of clinical studyNCT05720390 Effects of Intragastric Quinine, Alone or Combined With L-leucine, on Postprandi
→ Healthy
NCT06121869 Dileucine and Resistance Training Adaptations
→ Hypertrophy|Strength Training Adaptations|Weight-B
📊 Meta-Analyses
7 · systematic reviewCRD42022342953 Leucine Enriched Whey Protein on Measures of Sarcopenia
→ Sarcopenia is a state of age-related progressive l
CRD42022357780 Effects of Leucine-enriched amino acid/whey protein supplement and exercise inte
→ The European Working Group on Sarcopenia in Older
CRD42013004477 Leucine supplementation and body composition in the elderly: a systematic review
→ Anthropometric outcomes: body weight, BMI, lean bo
CRD42021227295 Assessing the leucine trigger and threshold hypothesis: a systematic and narrati
→ Nutritional metabolism relating to muscle health h
CRD42021243674 Effect of supplementation with leucine alone, together with other nutrients or w
→ Older adults are at a greater risk of developing s
CRD42023474941 Leucine Supplementation's Acute Effect on Recovery in Exercise: Systematic R
→ Leucine has been thought to augment adaptations to
CRD42023489418 Effects of leucine supplementation on muscle growth, strength, and recovery of a
→ It has been suggested that the leucine supplementa
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables