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⚗️ Ingredient

Malic acid

Open on HERB 2.0 ↗
2
Clinical Trials
1
Meta-Analyses
0
PubMed References
Top Conditions Studied with Malic acid
Xerostomia|Depression|Hypertension 1 Xerostomia 1 Xerostomia is the subjective sensation of dry mouth and is u 1
📋 Sample Trials
NCT04756986
Malic Acid in Treatment of Xerostomia
Unknown
NCT01652001
Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity
Completed · Phase 2|Phase 3
📊 Sample Meta-Analyses
CRD42021241322
Efficacy of a spray containing 1% malic acid in the treatment of Xerostomia: A systematic review and meta-analysis
Xerostomia is the subjective sensation of dry mouth and is usually (but not alwa
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Malic acid
⚗️ Identity
Name
Malic acid
Aliases / Synonyms
DL-malic acid; 6915-15-7; 2-Hydroxybutanedioic acid; 617-48-1; 2-Hydroxysuccinic acid; malate; Butanedioic acid, hydroxy-; hydroxysuccinic acid; Kyselina jablecna
🧪 Chemistry
Molecular Weight
134.0870
LogP
-1.0934
Drug-likeness
0.455
H-Bond Acceptors
3
H-Bond Donors
3
Rotatable Bonds
3
🔬 Structures
Canonical SMILES
C(C(C(=O)O)O)C(=O)O
Isomeric SMILES
C(C(C(=O)O)O)C(=O)O
InChIKey
BJEPYKJPYRNKOW-UHFFFAOYSA-N
InChI
InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
🔗 External References
HERB DB
HBIN034310 ↗
PubChem CID
525 ↗
NPASS
NPC51260
TCMID
24622; 13412
TCM-ID
2817
🔍 Raw view — every non-empty column on this row (29 fields)
name
Malic acid
common names
DL-malic acid; 6915-15-7; 2-Hydroxybutanedioic acid; 617-48-1; 2-Hydroxysuccinic acid; malate; Butanedioic acid, hydroxy-; hydroxysuccinic acid; Kyselina jablecna
herb ingredient id
HBIN034310
canonical smiles
C(C(C(=O)O)O)C(=O)O
isomeric smiles
C(C(C(=O)O)O)C(=O)O
inchi
InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
inchikey
BJEPYKJPYRNKOW-UHFFFAOYSA-N
mol wt
134.0870
num h acceptors
3
num h donors
3
mol logp
-1.0934
num rotatable bonds
3
drug likeness
0.455
tcmid ingredient id
24622; 13412
tcm id ingredient id
2817
pubchem cid
525
npass id
NPC51260

🏥 Linked Health Topics

1 · studied for these conditions (text bridge)
Xerostomia
disease

📋 Clinical Trials

2 · subject of clinical study
NCT04756986 Malic Acid in Treatment of Xerostomia
→ Xerostomia
NCT01652001 Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffer
→ Xerostomia|Depression|Hypertension

📊 Meta-Analyses

1 · systematic review
CRD42021241322 Efficacy of a spray containing 1% malic acid in the treatment of Xerostomia: A s
→ Xerostomia is the subjective sensation of dry mout
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables