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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Myoinositol

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Myoinositol

Polycystic Ovary Syndrome 6 PCOS 3 Infant, Newborn|Infant, Low Birth Weight|Infant, Small for G 2 Gestational Diabetes Mellitus 2 Gestational Diabetes 2 Myoinositol|Cryopreservation|Human|Sperm 1 Women Infertility 1 Alzheimer's Disease 1 Polycystic Ovary Syndrome|Infertility 1 Metabolic Syndrome|Cardiac Fibrosis 1 Acne Vulgaris 1 Type 2 Diabetes 1

📋 Sample Trials

NCT04745780

Evaluation of Efficacy and Safety of a Combination Containing Myo-inositol, D-chiro-inositol, Alpha-lactalbumin, Zinc and Extract of Gymnema Sylvestre in Subjects Diabetic Patients.

Completed

NCT01115127

Myo-inositol and Melatonin in Pre-menopausal Women

Completed · Phase 2|Phase 3

NCT00061997

Inositol in Preventing Lung Cancer in Patients With Bronchial Epithelial Dysplasia Who Are Current or Former Smokers

Completed · Phase 1

📊 Sample Meta-Analyses

CRD42017082275

Systematic review and meta-analysis of trials comparing markers of ovarian reserve and treatment outcomes following treatment with myo-inositol/di-chiro-inositol versus placebo/no treatment in women with polycystic ovary syndrome (PCOS) undergoing in-vitro fertilisation/intra-cytoplasmic sperm injection (IVF/ICSI) treatment.

Assisted Reproductive Technology. Polycystic Ovary Syndrome.

CRD42022380602

Study of comparative effectiveness and safety of metformin, myoinositol, life style changes and herbal medicines in improving endocrine and clinical variables in management PCOS patients a systematic review and a network meta-analysis.

Polycystic ovarian syndrome (PCOS) is the most common reason of infertility affe

CRD42023449705

Clinical Comparative Efficacy and Therapeutic Strategies for the Hashimoto's Thyroiditis: a Systematic Review and Network Meta-analysis.

Hashimoto’s thyroiditis (HT) is an autoimmune disease that destroys thyroid cell

📚 Sample References

PMID 34665453

The effect of metformin and myoinositol on metabolic outcomes in women with polycystic ovary syndrome: role of body mass and adiponectin in a randomized controlled trial

J Endocrinol Invest · 2021

PMID 35163126

Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats

Int J Mol Sci · 2022

PMID 36611810

Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis

Cells · 2023

⚗️ All Ingredient data fields for Myoinositol

⚗️ Identity

Name

Myoinositol

Aliases / Synonyms

inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; 87-89-8; meso-Inositol; D-chiro-Inositol

🧪 Chemistry

Molecular Weight

180.1560

LogP

-3.8346

Drug-likeness

0.227

H-Bond Acceptors

H-Bond Donors

🔬 Structures

Canonical SMILES

C1(C(C(C(C(C1O)O)O)O)O)O

Isomeric SMILES

C1(C(C(C(C(C1O)O)O)O)O)O

InChIKey

CDAISMWEOUEBRE-UHFFFAOYSA-N

InChI

InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H

🔗 External References

HERB DB

HBIN036059 ↗

PubChem CID

892 ↗

NPASS

NPC113212

HIT

C0557

TCMID

23297; 23298; 11082; 31316; 37030; 3880; 38187; 36818; 11081

TCM-ID

2484; 24770

🔍 Raw view — every non-empty column on this row (30 fields)

name

Myoinositol

common names

inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; 87-89-8; meso-Inositol; D-chiro-Inositol

herb ingredient id

HBIN036059

canonical smiles

C1(C(C(C(C(C1O)O)O)O)O)O

isomeric smiles

C1(C(C(C(C(C1O)O)O)O)O)O

inchi

InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H

inchikey

CDAISMWEOUEBRE-UHFFFAOYSA-N

mol wt

180.1560

num h acceptors

num h donors

mol logp

-3.8346

num rotatable bonds

drug likeness

0.227

tcmid ingredient id

23297; 23298; 11082; 31316; 37030; 3880; 38187; 36818; 11081

tcm id ingredient id

2484; 24770

pubchem cid

892

npass id

NPC113212

hit id

C0557

🏥 Linked Health Topics

6 · studied for these conditions (text bridge)

Polycystic Ovary Syndrome

syndrome

Gestational Diabetes

phenotype

📋 Clinical Trials

12 · subject of clinical study

NCT04745780 Evaluation of Efficacy and Safety of a Combination Containing Myo-inositol, D-ch

→ Type 2 Diabetes

NCT01115127 Myo-inositol and Melatonin in Pre-menopausal Women

→ Pre-menopausal Irregular Cycles and Bleedings

NCT00061997 Inositol in Preventing Lung Cancer in Patients With Bronchial Epithelial Dysplas

→ Lung Cancer|Precancerous Condition

NCT00349726 Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants

→ Infant, Newborn|Infant, Low Birth Weight|Infant, S

NCT00452829 Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PO

→ Recurrent Neural Tube Defects

NCT00783705 Inositol in Preventing Lung Cancer in Current or Former Smokers With Bronchial D

→ Non-small Cell Lung Cancer|Squamous Lung Dysplasia

NCT01030575 Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (I

→ Infant, Newborn|Infant, Low Birth Weight|Infant, S

NCT01047982 Myo-inositol in Obese Pregnant Women

→ Gestational Diabetes

NCT01342874 Improved Outcomes Associated With Inositol Dietary Supplementation in Women With

→ Gestational Diabetes Mellitus

NCT01396486 Inositol and Omega-3 Fatty Acids in Pediatric Mania

→ Pediatric Bipolar Spectrum Disorders

NCT01555190 Combination Therapy With Myo-inositol and Folic Acid Versus Myo-inositol Alone

→ Polycystic Ovary Syndrome|Hirsutism|Menstrual Irre

NCT01791647 Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome

→ Polycystic Ovary Syndrome

📊 Meta-Analyses

9 · systematic review

CRD42017082275 Systematic review and meta-analysis of trials comparing markers of ovarian reser

→ Assisted Reproductive Technology. Polycystic Ovary

CRD42022380602 Study of comparative effectiveness and safety of metformin, myoinositol, life st

→ Polycystic ovarian syndrome (PCOS) is the most com

CRD42023449705 Clinical Comparative Efficacy and Therapeutic Strategies for the Hashimoto's

→ Hashimoto’s thyroiditis (HT) is an autoimmune dise

CRD42023424883 Investigating the efficacy of natural products on metabolism and on endocrine st

→ Polycystic ovarian syndrome (PCOS) is one of the m

CRD42023459005 Role of dietary supplements in type 2 diabetes mellitus with coronary heart dise

→ Outcomes associated with populations in type 2 dia

CRD42023441257 Comparison of nutritional supplements in improving glycolipid metabolism and end

→ Polycystic ovary syndrome (PCOS) is a common gynec

CRD42023380584 Myoinositol for PCOS symptoms in adolescents: a systematic review

→ Polycystic ovarian syndrome (PCOS) in adolescent f

CRD42023433328 Effectiveness of inositol on oocyte and embryo quality in women undergoing repro

→ Inositol is a C6 sugar alcohol belonging to the B-

CRD42023437596 The effectiveness of four commonly used oral nutraceuticals in improving the Spe

→ Infertility is defined as being unable to conceive

📚 PubMed References

3 · cited research

PMID 34665453 The effect of metformin and myoinositol on metabolic outcomes in women with poly

J Endocrinol Invest

PMID 35163126 Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats

Int J Mol Sci

PMID 36611810 Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury vi

Cells

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables