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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
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Ingredient
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Gene Target
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
(-)-noradrenaline
21
Clinical Trials
28
Meta-Analyses
0
PubMed References
Top Conditions Studied with (-)-noradrenaline
treatment of maternal hypotension. parturients under cesarea 1
Norepinephrine|Hypotension|Anesthesiology|Major Abdominal Su 1
Pregnant women undergoing Caesarean section under neuraxial 1
Anesthesia|Pediatrics|Biliary Atresia 1
Anxiety, obsessive and stress-related disorders and its symp 1
This study will assess clinical outcomes after norepinephrin 1
Norepinephrine, Glypressin, Tourniquet Deflation|Hypotension 1
Phenylephrine has been used in cesarean delivery for a long 1
Anesthesia; Adverse Effect|Cesarean Section Complications 1
Alzheimer's disease (AD) is the most common form of dementia 1
The efficacy and safety of vasopressors; norepinephrine and 1
Intraoperative Hypotension 1
📋 Sample Trials
NCT05497700
Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related Hypotension
Unknown · Phase 3
NCT05368415
Comparison Between Three Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Ceaserian Section for Patients With Preeclampsia
Completed · Phase 4
NCT05521152
Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy
Completed · Phase 3
📊 Sample Meta-Analyses
CRD42017069090
Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) and placebo for anxiety, obsessive-compulsive and stress-related disorders: a systematic review and multilevel meta-analysis over the lifespan
Anxiety, obsessive and stress-related disorders and its symptom dimensions.
CRD42020208622
Vasopressin or norepinephrine in vasoplegic shock in surgical patients: Systematic review and meta-analysis
Vasoplegia is a common feature of all advanced shock states, with norepinephrine
CRD42018110903
Discontinuation sequence of norepinephrine and vasopressin in septic shock: a meta-analysis of the effect on hypotension incidence
Septic shock is an high mortality related disease where use of vasopressor is a
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for (-)-noradrenaline
⚗️ Identity
Name
(-)-noradrenaline
Aliases / Synonyms
norepinephrine; noradrenaline; L-Noradrenaline; 51-41-2; Levarterenol; Arterenol; (R)-Noradrenaline; (-)-Norepinephrine; L-Norepinephrine; Levophed
🧪 Chemistry
Molecular Weight
169.1800
LogP
0.0899
Drug-likeness
0.472
Oral Bioavailability
23.9620
H-Bond Acceptors
4
H-Bond Donors
4
Rotatable Bonds
2
🔬 Structures
Canonical SMILES
C1=CC(=C(C=C1C(CN)O)O)O
Isomeric SMILES
C1=CC(=C(C=C1[C@H](CN)O)O)O
InChIKey
SFLSHLFXELFNJZ-QMMMGPOBSA-N
InChI
InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
🔗 External References
HERB DB
PubChem CID
CAS Number
NPASS
NPC169207
HIT
C0255
SymMap
8232
TCMID
23053
TCMSP
MOL006654
🔍 Raw view — every non-empty column on this row (33 fields)
name
(-)-noradrenaline
common names
norepinephrine; noradrenaline; L-Noradrenaline; 51-41-2; Levarterenol; Arterenol; (R)-Noradrenaline; (-)-Norepinephrine; L-Norepinephrine; Levophed
herb ingredient id
HBIN037286
canonical smiles
C1=CC(=C(C=C1C(CN)O)O)O
isomeric smiles
C1=CC(=C(C=C1[C@H](CN)O)O)O
inchi
InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
inchikey
SFLSHLFXELFNJZ-QMMMGPOBSA-N
mol wt
169.1800
num h acceptors
4
num h donors
4
mol logp
0.0899
num rotatable bonds
2
drug likeness
0.472
ob score
23.9620
cas id
51-41-2
symmap mol id
8232
tcmid ingredient id
23053
tcmsp ingredient id
MOL006654
pubchem cid
439260
npass id
NPC169207
hit id
C0255
🏥 Linked Health Topics
2 · diseases via target pathways📋 Clinical Trials
12 · subject of clinical studyNCT05497700 Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia
→ Hypotension on Induction
NCT05368415 Comparison Between Three Norepinephrine Bolus Doses for Management of Post-spina
→ Anesthesia; Adverse Effect|Cesarean Section Compli
NCT05521152 Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoin
→ Anesthesia|Pediatrics|Biliary Atresia
NCT05264870 Norepinephrine in Caesarian Section
→ Cesarean Section Complications|Hemodynamic Instabi
NCT05248932 Norepinephrine to Prevent Hypotension in Ceasrean Delivery
→ Hypotension|Cesarean Section Complications
NCT05568160 Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Managem
→ Scheduled Cardiac Surgery With Extracorporeal Circ
NCT05276596 Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Post
→ Norepinephrine|Hypotension|Anesthesiology|Major Ab
NCT05502146 Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal
→ Spinal Anesthetic Toxicity|Hypotension Drug-Induce
NCT05290740 Two Norepinephrine Rescue Bolus Doses for Management of Severe Post-spinal Hypot
→ Postspinal Hypotension|Cesarean Delivery|Norepinep
NCT05492968 The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative He
→ Cardiac Output, Low|Cardiac Output, High|Perfusion
NCT05637164 Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for P
→ Norepinephrine|Post-induction Hypotension
NCT05355961 Effect of Norepinephrine Administration on Ventricular Systolic Function in Sept
→ Septic Shock
📊 Meta-Analyses
12 · systematic reviewCRD42017069090 Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin and Norepinephrine Re
→ Anxiety, obsessive and stress-related disorders an
CRD42020208622 Vasopressin or norepinephrine in vasoplegic shock in surgical patients: Systemat
→ Vasoplegia is a common feature of all advanced sho
CRD42018110903 Discontinuation sequence of norepinephrine and vasopressin in septic shock: a me
→ Septic shock is an high mortality related disease
CRD42018111731 Norepinephrine versus phenylephrine for management of maternal hypotension durin
→ Maternal hypotension is a physiological response d
CRD42018112816 Epinephrine and norepinephrine in Alzheimer’s disease: a systematic review and m
→ Alzheimer's disease (AD) is the most common form o
CRD42019121885 Norepinephrine vs Phenylephrine in cesarean delivery under spinal anesthesia: a
→ Norepinephrine and phenylephine for the treatment
CRD42019125873 Effect of serotonin-norepinephrine reuptake inhibitors for patients with chemoth
→ Peripheral neuropathy occurs with destruction of p
CRD42020142650 Pharmacological norepinephrine transporter inhibition for the prevention of vaso
→ Vasovagal syncope (VVS) is the most common form of
CRD42019144653 Norepinephrine in septic shock: a systematic review and meta-analysis
→ Sepsis remains to be one of the significant causes
CRD42020156979 Efficacy and safety of norepinephrine for management of spinal induced hypotensi
→ Spinal Induced Hypotesion is the most common probl
CRD42021168620 The effects of norepinephrine compared to other vasopressors on perioperative cl
→ This study will assess clinical outcomes after nor
CRD42020180208 Systematic review and meta-analysis of comparison between norepinephrine and phe
→ treatment of maternal hypotension. parturients und
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables