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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Oleovitamin a

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Oleovitamin a

Vitamin A Deficiency 8 Mortality|Morbidity 3 Retinitis Pigmentosa 2 Visceral Leishmaniasis 1 HIV Infections|Vitamin A Deficiency|HIV Seronegativity 1 Pneumonia|Diarrhea|Acute Upper Respiratory Tract Infections 1 Allogeneic Hematopoietic Stem Cell Transplantation Recipient 1 COVID-19 (viral respiratory illness) and its clinical conseq 1 Iron Metabolic Homeostasis 1 Village Children 1 Hematopoietic Stem Cell Transplant 1 Photodamaged Skin|Wrinkles 1

📋 Sample Trials

NCT00363038

Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising

Completed

NCT03112863

Comparison of the Cosmetic Effects of Bakuchiol and Retinol

Completed · Early_Phase 1

NCT00198822

Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh

Completed · Phase 3

📊 Sample Meta-Analyses

CRD42019110521

The accuracy of methods compared to HPLC for the diagnosis of vitamin A deficiency based on concentrations of serum retinol

Vitamin A deficiency, as defined by low serum retinol concentrations.

CRD42020215816

Retinol binding protein 4 level and risk of gestational diabetes mellitus: a meta analysis in prospective studies

Gestational diabetes mellitus occurs when beta cell dysfunction fails to compens

CRD42021259719

Sensitivity and Specificity of Serum Retinol as Vitamin A status indicator: meta-analysis and systematic review

📚 Sample References

PMID 34508587

The vitamin A transporter STRA6 adjusts the stoichiometry of chromophore and opsins in visual pigment synthesis and recycling

Hum Mol Genet · 2021

PMID 35464265

Xanthophyll β-cryptoxanthin treatment inhibits hepatic steatosis without altering vitamin A status in β-carotene 9',10'-oxygenase knockout mice

Hepatobiliary Surg Nutr · 2022

PMID 35493071

Retinol Binding Protein 7 Promotes Adipogenesis in vitro and Regulates Expression of Genes Involved in Retinol Metabolism

Front Cell Dev Biol · 2022

⚗️ All Ingredient data fields for Oleovitamin a

⚗️ Identity

Name

Oleovitamin a

Aliases / Synonyms

retinol; Vitamin A; all-trans-Retinol; 68-26-8; Vitamin A1; Alphalin; Chocola A; Alphasterol; Apostavit; Aquasynth

🧪 Chemistry

Molecular Weight

286.4590

LogP

5.5103

Drug-likeness

0.661

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C

Isomeric SMILES

CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/CO)/C)/C

InChIKey

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

InChI

InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

🔗 External References

HERB DB

HBIN038043 ↗

PubChem CID

445354 ↗

NPASS

NPC55412

HIT

C0366

SymMap

19408

TCMID

31755

🔍 Raw view — every non-empty column on this row (30 fields)

name

Oleovitamin a

common names

retinol; Vitamin A; all-trans-Retinol; 68-26-8; Vitamin A1; Alphalin; Chocola A; Alphasterol; Apostavit; Aquasynth

herb ingredient id

HBIN038043

canonical smiles

CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C

isomeric smiles

CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/CO)/C)/C

inchi

InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

inchikey

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

mol wt

286.4590

num h acceptors

num h donors

mol logp

5.5103

num rotatable bonds

drug likeness

0.661

symmap mol id

19408

tcmid ingredient id

31755

pubchem cid

445354

npass id

NPC55412

hit id

C0366

🏥 Linked Health Topics

9 · studied for these conditions (text bridge)

Retinopathy of Prematurity

📋 Clinical Trials

12 · subject of clinical study

NCT00363038 Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Br

→ Ecchymosis

NCT03112863 Comparison of the Cosmetic Effects of Bakuchiol and Retinol

→ Wrinkle|Photoaging

NCT00198822 Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and In

→ Vitamin A Deficiency|Maternal Mortality|Infant Mor

NCT00712647 Carotene and Retinol Efficacy Trial

→ Lung Cancer

NCT00000114 Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmen

→ Retinitis Pigmentosa

NCT00053612 Vitamin A to Reduce HIV in Vaginal Secretions and Prevent Viral Transmission

→ HIV Infections|Vitamin A Deficiency|HIV Seronegati

NCT00065455 Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa

→ Retinitis Pigmentosa

NCT00114868 Vitamin A Supplementation in Newborns Study

→ Infant, Newborn

NCT00168584 Different Doses of Vitamin A and Childhood Morbidity and Mortality

→ Mortality|Morbidity

NCT00168597 Vitamin A With BCG Vaccine

→ Mortality|Morbidity

NCT00168636 Different Doses of Vitamin A Supplementation and Male and Female Morbidity and M

→ Mortality|Morbidity

NCT00211341 Trial of the Impact of Vitamin A on Maternal Mortality

→ Vitamin A Deficiency|Maternal Mortality|Maternal M

📊 Meta-Analyses

7 · systematic review

CRD42019110521 The accuracy of methods compared to HPLC for the diagnosis of vitamin A deficien

→ Vitamin A deficiency, as defined by low serum reti

CRD42020215816 Retinol binding protein 4 level and risk of gestational diabetes mellitus: a met

→ Gestational diabetes mellitus occurs when beta cel

CRD42021259719 Sensitivity and Specificity of Serum Retinol as Vitamin A status indicator: meta

CRD42022300224 The association between circulating retinol binding protein 4 levels and NAFLD:

→ Serum retinol binding protein 4, NAFLD

CRD42022362281 The association between circulating retinol binding protein 4 levels and NAFLD:

→ Serum retinol binding protein 4, NAFLD.

CRD42023418843 The effects of nutrition interventions on adverse perinatal outcomes: an umbrell

→ To evaluate the quality of evidence and effectiven

CRD42023430805 Role of antioxidant therapy in the treatment and prognosis of COVID-19: a system

→ COVID-19 (viral respiratory illness) and its clini

📚 PubMed References

4 · cited research

PMID 34508587 The vitamin A transporter STRA6 adjusts the stoichiometry of chromophore and ops

Hum Mol Genet

PMID 35464265 Xanthophyll β-cryptoxanthin treatment inhibits hepatic steatosis without alterin

Hepatobiliary Surg Nutr

PMID 35493071 Retinol Binding Protein 7 Promotes Adipogenesis in vitro and Regulates Expressio

Front Cell Dev Biol

PMID 36030930 Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces f

J Lipid Res

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables