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Ingredient
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Gene Target
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
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⚗️ Ingredient

Ornithine

Open on HERB 2.0 ↗
2
Clinical Trials
3
Meta-Analyses
1
PubMed References
Top Conditions Studied with Ornithine
The Cochrane Hepato-Biliary Group 2 Non-alcoholic Fatty Liver Disease 1 Cirrhosis 1 There were an estimated 4.8 million new cases of gastrointes 1
📋 Sample Trials
NCT05042245
The Efficacy and Safety of Ornithine Aspartic Acid Granules in NAFLD Against Silymarin Capsules
Unknown · Phase 4
NCT05737030
Effect of L-ornithine-L-aspertate (LOLA) on the Gut Microbiome
Recruiting · Phase 4
📊 Sample Meta-Analyses
CRD42017055017
L-ornithine L-aspartate for people with cirrhosis and hepatic encephalopathy [Cochrane Protocol]
The Cochrane Hepato-Biliary Group
CRD42017082998
L-ornithine L-aspartate for people with cirrhosis and hepatic encephalopathy [Cochrane protocol]
The Cochrane Hepato-Biliary Group
CRD42022309307
The use of Eflornithine for chemoprevention of gastrointestinal cancers
There were an estimated 4.8 million new cases of gastrointestinal (GI) cancers a
📚 Sample References
PMID 34836006
Additive Effects of L-Ornithine on Preferences to Basic Taste Solutions in Mice
Nutrients · 2021
⚗️ All Ingredient data fields for Ornithine
⚗️ Identity
Name
Ornithine
Aliases / Synonyms
L-ornithine; 70-26-8; (S)-2,5-Diaminopentanoic acid; (S)-Ornithine; (S)-2,5-diaminovaleric acid; (2S)-2,5-diaminopentanoic acid; Ornithine [INN]; L-Norvaline, 5-amino-; (S)-alpha,delta-Diaminovaleric acid
🧪 Chemistry
Molecular Weight
132.1630
LogP
-0.8628
Drug-likeness
0.464
H-Bond Acceptors
3
H-Bond Donors
3
Rotatable Bonds
4
🔬 Structures
Canonical SMILES
C(CC(C(=O)O)N)CN
Isomeric SMILES
C(C[C@@H](C(=O)O)N)CN
InChIKey
AHLPHDHHMVZTML-BYPYZUCNSA-N
InChI
InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
🔗 External References
HERB DB
HBIN038287 ↗
PubChem CID
6262 ↗
TCMID
16197
🔍 Raw view — every non-empty column on this row (27 fields)
name
Ornithine
common names
L-ornithine; 70-26-8; (S)-2,5-Diaminopentanoic acid; (S)-Ornithine; (S)-2,5-diaminovaleric acid; (2S)-2,5-diaminopentanoic acid; Ornithine [INN]; L-Norvaline, 5-amino-; (S)-alpha,delta-Diaminovaleric acid
herb ingredient id
HBIN038287
canonical smiles
C(CC(C(=O)O)N)CN
isomeric smiles
C(C[C@@H](C(=O)O)N)CN
inchi
InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
inchikey
AHLPHDHHMVZTML-BYPYZUCNSA-N
mol wt
132.1630
num h acceptors
3
num h donors
3
mol logp
-0.8628
num rotatable bonds
4
drug likeness
0.464
tcmid ingredient id
16197
pubchem cid
6262

🏥 Linked Health Topics

2 · diseases via target pathways
Non-Alcoholic Fatty Liver Disease
syndrome
Cirrhosis
syndrome

📋 Clinical Trials

2 · subject of clinical study
NCT05042245 The Efficacy and Safety of Ornithine Aspartic Acid Granules in NAFLD Against Sil
→ Non-alcoholic Fatty Liver Disease
NCT05737030 Effect of L-ornithine-L-aspertate (LOLA) on the Gut Microbiome
→ Cirrhosis

📊 Meta-Analyses

3 · systematic review
CRD42017055017 L-ornithine L-aspartate for people with cirrhosis and hepatic encephalopathy [Co
→ The Cochrane Hepato-Biliary Group
CRD42017082998 L-ornithine L-aspartate for people with cirrhosis and hepatic encephalopathy [Co
→ The Cochrane Hepato-Biliary Group
CRD42022309307 The use of Eflornithine for chemoprevention of gastrointestinal cancers
→ There were an estimated 4.8 million new cases of g

📚 PubMed References

1 · cited research
PMID 34836006 Additive Effects of L-Ornithine on Preferences to Basic Taste Solutions in Mice
Nutrients
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables