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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Prostaglandin e1

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Prostaglandin e1

Stage II Peripheral Arterial Occlusive Disease|Intermittent 1 Pyloric Stenosis;Acquired|Congenital Heart Disease 1

📋 Sample Trials

NCT01263925

Prostaglandin E1 in Outpatients With Intermittent Claudication

Completed · Phase 3

NCT04496050

Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns

Unknown

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

PMID 31685975

Prostaglandin E1 attenuates high glucose-induced apoptosis in proximal renal tubular cells by inhibiting the JNK/Bim pathway

Acta Pharmacol Sin · 2020

⚗️ All Ingredient data fields for Prostaglandin e1

⚗️ Identity

Name

Prostaglandin e1

Aliases / Synonyms

alprostadil; 745-65-3; PGE1; Edex; Caverject; Muse; Prostin VR; Befar; Alprostadilum

🧪 Chemistry

Molecular Weight

354.4870

LogP

3.4751

Drug-likeness

0.348

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O

Isomeric SMILES

CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

InChIKey

GMVPRGQOIOIIMI-DWKJAMRDSA-N

InChI

InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

🔗 External References

HERB DB

HBIN040885 ↗

PubChem CID

5280723 ↗

DrugBank

DB00770 ↗

TCMID

17940

🔍 Raw view — every non-empty column on this row (28 fields)

name

Prostaglandin e1

common names

alprostadil; 745-65-3; PGE1; Edex; Caverject; Muse; Prostin VR; Befar; Alprostadilum

herb ingredient id

HBIN040885

canonical smiles

CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O

isomeric smiles

CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

inchi

InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

inchikey

GMVPRGQOIOIIMI-DWKJAMRDSA-N

mol wt

354.4870

num h acceptors

num h donors

mol logp

3.4751

num rotatable bonds

drug likeness

0.348

tcmid ingredient id

17940

pubchem cid

5280723

drugbank id

DB00770

📋 Clinical Trials

2 · subject of clinical study

NCT01263925 Prostaglandin E1 in Outpatients With Intermittent Claudication

→ Stage II Peripheral Arterial Occlusive Disease|Int

NCT04496050 Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns

→ Pyloric Stenosis;Acquired|Congenital Heart Disease

📚 PubMed References

1 · cited research

PMID 31685975 Prostaglandin E1 attenuates high glucose-induced apoptosis in proximal renal tub

Acta Pharmacol Sin

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables