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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Saccharose

Open on HERB 2.0 ↗

Clinical Trials

116

Meta-Analyses

PubMed References

Top Conditions Studied with Saccharose

Pain 9 Overweight 2 Healthy 2 We are interested in examining the adverse effects of consum 2 Condition: Healthy adolescent/adult populations, adolescents 2 Sugar-sweetened beverage; cardiovascular disease; major card 1 Negative emotional states such as anxiety and depression. 1 Childhood obesity. Interventions to reduce sugar-sweetened b 1 Healthy|Human Gut Microflora 1 School-based interventions for the reduction of sugar and su 1 Gingivitis, defined as the inflammation of the gums and a pr 1 Addictiveness of sugar 1

📋 Sample Trials

NCT02134873

Sucrose Practices for Pain in Neonates

Completed

NCT02015442

Effect of Sucrose on Liver Fat

Completed

NCT04804397

Effects of Sucrose Added Blind to the Diet Over Eight Weeks on Body Mass and Weight in Men

Completed

📊 Sample Meta-Analyses

CRD42021239762

Antiplaque and antigingivitis efficacy of sugar-free chewing gums with or without active ingredients as an adjunct to toothbrushing: a systematic review

Only studies that involved adults (aged at least 18 years old) with gingivitis w

CRD42018094676

The role of sugar-free gum in oral care: a systematic review

Oral health.

CRD42014009638

Do sugar-sweetened beverages cause adverse health outcomes in adults? A systematic review protocol

We are interested in examining the adverse effects of consuming sugar-sweetened

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Saccharose

⚗️ Identity

Name

Saccharose

Aliases / Synonyms

sucrose; 57-50-1; sugar; Table sugar; Cane sugar; White sugar; D-Sucrose; Rohrzucker; Saccharum

🧪 Chemistry

Molecular Weight

342.2970

LogP

-5.3956

Drug-likeness

0.238

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O

Isomeric SMILES

C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CO)O)O)CO)O)O)O)O

InChIKey

CZMRCDWAGMRECN-UGDNZRGBSA-N

InChI

InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1

🔗 External References

HERB DB

HBIN042735 ↗

PubChem CID

5988 ↗

NPASS

NPC130683

HIT

C0569

TCMID

33350; 33351; 34234

🔍 Raw view — every non-empty column on this row (29 fields)

name

Saccharose

common names

sucrose; 57-50-1; sugar; Table sugar; Cane sugar; White sugar; D-Sucrose; Rohrzucker; Saccharum

herb ingredient id

HBIN042735

canonical smiles

C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O

isomeric smiles

C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CO)O)O)CO)O)O)O)O

inchi

InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1

inchikey

CZMRCDWAGMRECN-UGDNZRGBSA-N

mol wt

342.2970

num h acceptors

num h donors

mol logp

-5.3956

num rotatable bonds

drug likeness

0.238

tcmid ingredient id

33350; 33351; 34234

pubchem cid

5988

npass id

NPC130683

hit id

C0569

🏥 Linked Health Topics

5 · studied for these conditions (text bridge)

Pain

phenotype

Retinopathy of Prematurity

Overweight And Obesity

syndrome

📋 Clinical Trials

12 · subject of clinical study

NCT02134873 Sucrose Practices for Pain in Neonates

→ Pain

NCT02015442 Effect of Sucrose on Liver Fat

→ Healthy Volunteers

NCT04804397 Effects of Sucrose Added Blind to the Diet Over Eight Weeks on Body Mass and Wei

→ Overweight

NCT02725814 Sucrose Practices for Pain in Neonates Part B

→ Pain

NCT00949104 Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preter

→ Pain in Preterm Neonates

NCT04486105 Chronic Sucrose Intake, Markers of Health and Biomarker Identification

→ Dietary Exposure|Metabolic Disturbance

NCT00921544 Sucrose Analgesia for the Reduction of Pain During Retinopathy of Prematurity Sc

→ Retinopathy of Prematurity

NCT01931020 Analgesic Effect of Oral 25% Glucose Versus Oral 24% Sucrose for Pain Relief Dur

→ Pain

NCT02344368 The Effect of Sucrose on Pain Relief During Venous Blood Sampling in Preterm Inf

→ Pain

NCT03082001 Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth

→ Neonate|Pain|ELBW

NCT02728141 Healthy Infant Development Project - Sucrose Component

→ Iron Deficiency

NCT04898881 Breast Milk vs Sucrose in Relieving Procedural Pain in Preterm Neonates During B

→ Pain

📊 Meta-Analyses

12 · systematic review

CRD42021239762 Antiplaque and antigingivitis efficacy of sugar-free chewing gums with or withou

→ Only studies that involved adults (aged at least 1

CRD42018094676 The role of sugar-free gum in oral care: a systematic review

→ Oral health.

CRD42014009638 Do sugar-sweetened beverages cause adverse health outcomes in adults? A systemat

→ We are interested in examining the adverse effects

CRD42014009641 Do sugar-sweetened beverages cause adverse health outcomes in children? A system

→ We are interested in examining the adverse effects

CRD42022307003 Consumption of sugar sweetened beverages, artificially sweetened beverages and f

→ Hypertension, type 2 diabetes, coronary heart dise

CRD42022353683 Assessment The effectiveness of anaerobic digesters in the treatment of sugarcan

→ This research includes interventional studies that

CRD42020208952 Enablers and barriers for Sugar-Sweetened Beverage (SSB) Tax: A Systematic Revie

→ Obesity can be described as the accumulation of ex

CRD42012002379 Effect of dietary sugar intake on blood pressure

→ Blood pressure is commonly defined as the pressure

CRD42012002437 The effect of dietary sugar intake on blood lipids

→ Due to the link between overweight and obesity and

CRD42021259128 Sugar intake and risk of hypertension: a systematic review and dose–response met

→ Hypertension is a major risk factor for developing

CRD42022347984 The effect of free sugars on cognitive function: a systematic review and meta-an

→ Cognitive function refers to the ability to perfor

CRD42022354148 The association between the consumption of sugar-sweetened beverages (SSB) or ar

→ We explore multiple health-related outcomes: metab

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables