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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Salicylic acid

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Salicylic acid

Chronic Rhinosinusitis|Aspirin Exacerbated Respiratory Disea 1 Acne Vulgaris 1 The Cochrane Skin Group 1 Acne vulgaris (AV) is a chronic inflammatory skin disease of 1 Acanthosis Nigricans(AN) is a skin condition that manifests 1

📋 Sample Trials

NCT01778465

Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease

Completed

NCT05712837

Efficacy of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild to Moderate Acne Vulgaris

Completed

📊 Sample Meta-Analyses

CRD42015020787

Topical azelaic acid, salicylic acid, nicotinamide, and sulphur for acne [Cochrane Protocol]

The Cochrane Skin Group

CRD42022328414

Efficacy and safety of fire needle therapy combined with 30% supramolecular salicylic acid for acne vulgaris: A systematic review and meta-analysis of randomized controlled trials

Acne vulgaris (AV) is a chronic inflammatory skin disease of the pilosebaceous f

CRD42023444441

Comparison on the Effectiveness of different Treatment modalities for Acanthosis Nigricans: A Systematic Review and Meta-analysis

Acanthosis Nigricans(AN) is a skin condition that manifests as thickened hyperpi

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Salicylic acid

⚗️ Identity

Name

Salicylic acid

Aliases / Synonyms

2-Hydroxybenzoic acid; 69-72-7; o-hydroxybenzoic acid; 2-Carboxyphenol; o-Carboxyphenol; Rutranex; Salonil; Retarder W; Duoplant

🧪 Chemistry

Molecular Weight

138.1220

LogP

1.0904

Drug-likeness

0.61

Oral Bioavailability

32.1270

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C1=CC=C(C(=C1)C(=O)O)O

Isomeric SMILES

C1=CC=C(C(=C1)C(=O)O)O

InChIKey

YGSDEFSMJLZEOE-UHFFFAOYSA-N

InChI

InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

🔗 External References

HERB DB

HBIN042852 ↗

PubChem CID

338 ↗

CAS Number

69-72-7 ↗

NPASS

NPC20045

TCMID

23230; 19173; 19172

TCMSP

MOL001801

TCM-ID

1299

🔍 Raw view — every non-empty column on this row (32 fields)

name

Salicylic acid

common names

2-Hydroxybenzoic acid; 69-72-7; o-hydroxybenzoic acid; 2-Carboxyphenol; o-Carboxyphenol; Rutranex; Salonil; Retarder W; Duoplant

herb ingredient id

HBIN042852

canonical smiles

C1=CC=C(C(=C1)C(=O)O)O

isomeric smiles

C1=CC=C(C(=C1)C(=O)O)O

inchi

InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

inchikey

YGSDEFSMJLZEOE-UHFFFAOYSA-N

mol wt

138.1220

num h acceptors

num h donors

mol logp

1.0904

num rotatable bonds

drug likeness

0.61

ob score

32.1270

cas id

69-72-7

tcmid ingredient id

23230; 19173; 19172

tcmsp ingredient id

MOL001801

tcm id ingredient id

1299

pubchem cid

338

npass id

NPC20045

🏥 Linked Health Topics

1 · studied for these conditions (text bridge)

Acne Vulgaris

syndrome

📋 Clinical Trials

2 · subject of clinical study

NCT01778465 Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease

→ Chronic Rhinosinusitis|Aspirin Exacerbated Respira

NCT05712837 Efficacy of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild

→ Acne Vulgaris

📊 Meta-Analyses

3 · systematic review

CRD42015020787 Topical azelaic acid, salicylic acid, nicotinamide, and sulphur for acne [Cochra

→ The Cochrane Skin Group

CRD42022328414 Efficacy and safety of fire needle therapy combined with 30% supramolecular sali

→ Acne vulgaris (AV) is a chronic inflammatory skin

CRD42023444441 Comparison on the Effectiveness of different Treatment modalities for Acanthosis

→ Acanthosis Nigricans(AN) is a skin condition that

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables