AlternativeMed
Ancient Wisdom Natural Remedies Modern Wellness
Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿
Herb
6,826
→
⚗️
Ingredient
44,598
→
🧬
Gene Target
15,695
→
🏥
Disease
30,467
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins
⚗️ Ingredient

(s)-serine

Open on HERB 2.0 ↗
4
Clinical Trials
0
Meta-Analyses
0
PubMed References
Top Conditions Studied with (s)-serine
Amyotrophic Lateral Sclerosis (ALS) 1 Alzheimer Disease 1 Hereditary Sensory and Autonomic Neuropathy Type I 1 GRIN Related Disorders 1
📋 Sample Trials
NCT01733407
L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1
Completed · Phase 1|Phase 2
NCT03580616
Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS)
Terminated · Phase 2
NCT04646447
Tolerability and Efficacy of L-Serine in Patients With GRIN-related Encephalopathy
Unknown
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for (s)-serine
⚗️ Identity
Name
(s)-serine
Aliases / Synonyms
L-serine; serine; 56-45-1; (S)-2-Amino-3-hydroxypropanoic acid; H-Ser-OH; beta-Hydroxyalanine; L-(-)-Serine; L-ser; Serine, L-
🧪 Chemistry
Molecular Weight
105.0930
LogP
-1.6094
Drug-likeness
0.394
H-Bond Acceptors
3
H-Bond Donors
3
Rotatable Bonds
2
🔬 Structures
Canonical SMILES
C(C(C(=O)O)N)O
Isomeric SMILES
C([C@@H](C(=O)O)N)O
InChIKey
MTCFGRXMJLQNBG-REOHCLBHSA-N
InChI
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
🔗 External References
HERB DB
HBIN044676 ↗
PubChem CID
5951 ↗
SymMap
17681
TCMID
19744; 33343
🔍 Raw view — every non-empty column on this row (28 fields)
name
(s)-serine
common names
L-serine; serine; 56-45-1; (S)-2-Amino-3-hydroxypropanoic acid; H-Ser-OH; beta-Hydroxyalanine; L-(-)-Serine; L-ser; Serine, L-
herb ingredient id
HBIN044676
canonical smiles
C(C(C(=O)O)N)O
isomeric smiles
C([C@@H](C(=O)O)N)O
inchi
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
inchikey
MTCFGRXMJLQNBG-REOHCLBHSA-N
mol wt
105.0930
num h acceptors
3
num h donors
3
mol logp
-1.6094
num rotatable bonds
2
drug likeness
0.394
symmap mol id
17681
tcmid ingredient id
19744; 33343
pubchem cid
5951

📋 Clinical Trials

4 · subject of clinical study
NCT01733407 L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1
→ Hereditary Sensory and Autonomic Neuropathy Type I
NCT03580616 Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Scler
→ Amyotrophic Lateral Sclerosis (ALS)
NCT04646447 Tolerability and Efficacy of L-Serine in Patients With GRIN-related Encephalopat
→ GRIN Related Disorders
NCT03062449 Phase IIa L-serine Trial for eAD
→ Alzheimer Disease
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables