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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Tatarine

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Tatarine

Obesity 2 Gastric Cancer 2 Psychotic Disorders 1 Cardiovascular Risk 1 Taurine is considered to be an immune modulator. It is not i 1 Peripartum Cardiomyopathy 1 Bipolar Disorder|Mania|Bipolar Depression 1 Rheumatoid arthritis 1 Periodontitis 1 Recent clinical studies have shown that the appropriate use 1 Oxidative Stress 1 Mild cognitive impairment (MCI) refers to a common condition 1

📋 Sample Trials

NCT01421979

Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in Humans

Completed

NCT00217165

Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study

Completed · Phase 2

NCT00497978

The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient

Completed

📊 Sample Meta-Analyses

CRD42021285986

The effect of taurine supplementation on cognition for patients with mild cognitive impairment: A systematic review and meta-analysis

Mild cognitive impairment (MCI) refers to a common condition in the elderly with

CRD42018087417

Effect of taurine amino acid on advanced glycation end products (AGEs) in vivo and in vitro studies: a systematic review

Advanced glycation end products (AGEs) are damaging compound that are generated

CRD42021225243

Dose response of taurine on aerobic and strength exercises: A systematic approach

We included studies for systematic review that reported participants who perform

📚 Sample References

PMID 32017914

Taurine protects against cardiac dysfunction induced by pressure overload through SIRT1-p53 activation

Chem Biol Interact · 2020

PMID 32407847

Taurine and hesperidin rescues carbon tetrachloride-triggered testicular and kidney damage in rats via modulating oxidative stress and inflammation

Life Sci · 2020

PMID 32566100

Taurine Attenuates Carcinogenicity in Ulcerative Colitis-Colorectal Cancer Mouse Model

Oxid Med Cell Longev · 2020

⚗️ All Ingredient data fields for Tatarine

⚗️ Identity

Name

Tatarine

Aliases / Synonyms

taurine; 2-aminoethanesulfonic acid; 107-35-7; Ethanesulfonic acid, 2-amino-; tauphon; L-Taurine; 2-Aminoethylsulfonic acid; 2-Sulfoethylamine; O-Due; taufon

🧪 Chemistry

Molecular Weight

125.1490

LogP

-1.1671

Drug-likeness

0.456

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C(CS(=O)(=O)O)N

Isomeric SMILES

C(CS(=O)(=O)O)N

InChIKey

XOAAWQZATWQOTB-UHFFFAOYSA-N

InChI

InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

🔗 External References

HERB DB

HBIN045566 ↗

PubChem CID

1123 ↗

HIT

C0561

TCMID

38734

🔍 Raw view — every non-empty column on this row (28 fields)

name

Tatarine

common names

taurine; 2-aminoethanesulfonic acid; 107-35-7; Ethanesulfonic acid, 2-amino-; tauphon; L-Taurine; 2-Aminoethylsulfonic acid; 2-Sulfoethylamine; O-Due; taufon

herb ingredient id

HBIN045566

canonical smiles

C(CS(=O)(=O)O)N

isomeric smiles

C(CS(=O)(=O)O)N

inchi

InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

inchikey

XOAAWQZATWQOTB-UHFFFAOYSA-N

mol wt

125.1490

num h acceptors

num h donors

mol logp

-1.1671

num rotatable bonds

drug likeness

0.456

tcmid ingredient id

38734

pubchem cid

1123

hit id

C0561

🏥 Linked Health Topics

6 · studied for these conditions (text bridge)

Peripartum Cardiomyopathy

phenotype

📋 Clinical Trials

12 · subject of clinical study

NCT01421979 Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) t

→ Cardiovascular Risk

NCT00217165 Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study

→ Bipolar Disorder|Mania|Bipolar Depression

NCT00497978 The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Pat

→ Insulin Resistance|Elderly Patient|Oxidative Stres

NCT01192828 Oxidative Stress Markers In Inherited Homocystinuria And The Impact Of Taurine

→ Homocystinuria

NCT03907267 Taurine in Peripartum Cardiomyopathy

→ Peripartum Cardiomyopathy

NCT04047043 Evaluation of Serum Taurine as a Prognostic Marker for Graft Function in Adult E

→ Taurine

NCT04192539 The Prospect of Using Serum Taurine Level as a Potential Biomarker for Early Det

→ Taurine in Cancer Colon

NCT04279600 Taurine Supplementation and Training Effects on Energy Metabolism, Inflammation

→ Obesity

NCT04646512 Taurine Supplementation and Exercise on Irisin Levels in Obesity

→ Obesity

NCT04772508 Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.

→ Periodontitis

NCT04874012 Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With

→ Diabetes Mellitus, Type 2

NCT05149716 Taurine as a Possible Anti-aging Therapy?

→ Oxidative Stress

📊 Meta-Analyses

10 · systematic review

CRD42021285986 The effect of taurine supplementation on cognition for patients with mild cognit

→ Mild cognitive impairment (MCI) refers to a common

CRD42018087417 Effect of taurine amino acid on advanced glycation end products (AGEs) in vivo a

→ Advanced glycation end products (AGEs) are damagin

CRD42021225243 Dose response of taurine on aerobic and strength exercises: A systematic approac

→ We included studies for systematic review that rep

CRD42021227649 Effects of taurine on rheumatoid arthritis: A systematic review

→ Rheumatoid arthritis

CRD42021241114 Effect of taurine administration on symptoms, severity, or clinical outcome of d

→ Dilated cardiomyopathy (DCM) Heart failure (HF)

CRD42022307677 The effects of taurine supplementation on Diabete mellitus in humans: a systemat

→ The nutritional supplement taurine is expected to

CRD42022315337 Effect of taurine - fortified enteral nutrition on prognosis in critically ill p

→ Taurine is considered to be an immune modulator. I

CRD42022325835 taurine supplementation and cardiovascular risk factors: systematic review and m

→ In this review the effect of taurine on cardiovasc

CRD42023391661 The acute effect of energy drink with taurine on resting blood pressure in healt

→ We will evaluate healthy young subjects.

CRD42023409624 Efficacy of immunonutrition in burn patients: systematic review and network meta

→ Recent clinical studies have shown that the approp

📚 PubMed References

12 · cited research

PMID 32017914 Taurine protects against cardiac dysfunction induced by pressure overload throug

Chem Biol Interact

PMID 32407847 Taurine and hesperidin rescues carbon tetrachloride-triggered testicular and kid

Life Sci

PMID 32566100 Taurine Attenuates Carcinogenicity in Ulcerative Colitis-Colorectal Cancer Mouse

Oxid Med Cell Longev

PMID 32962196 Taurine Inhibits Glucocorticoid-Induced Bone Mitochondrial Injury, Preventing Os

Int J Mol Sci

PMID 33525569 Cytoprotective Effects of Taurine on Heat-Induced Bovine Mammary Epithelial Cell

Cells

PMID 33777017 Taurine Alleviates Streptococcus uberis- Induced Inflammation by Activating Auto

Front Immunol

PMID 33912173 Taurine Antagonizes Macrophages M1 Polarization by Mitophagy-Glycolysis Switch B

Front Immunol

PMID 33937232 Taurine Attenuates the Hypotaurine-Induced Progression of CRC via ERK/RSK Signal

Front Cell Dev Biol

PMID 34040692 Taurine Increases Zinc Preconditioning-Induced Prevention of Nitrosative Stress,

Oxid Med Cell Longev

PMID 34124164 Taurine Protects C2C12 Myoblasts From Impaired Cell Proliferation and Myotube Di

Front Mol Biosci

PMID 34139304 On the mechanisms of taurine in alleviating electrocardiographic, hemodynamic, a

Food Chem Toxicol

PMID 34693866 Microbial contribution to the caloric restriction-triggered regulation of the in

Gut Microbes

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables