AlternativeMed
Ancient Wisdom Natural Remedies Modern Wellness
Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿
Herb
6,826
→
⚗️
Ingredient
44,595
→
🧬
Gene Target
15,505
→
🏥
Disease
30,170
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Da Ma Green Tea Common Olive Peanut Ginkgo Leaf; Ginkgo Folium Pomegranate Fruit Sucrose Cocoa Linseed Honey
🌿 Herb

Apple

Open on HERB 2.0 ↗
10
Clinical Trials
1
Meta-Analyses
2
PubMed References
Top Conditions Studied with Apple
Cardiovascular Diseases 1 Cardiovascular Disease 1 All randomized controlled trial studies investigated the bio 1 Oxidative Stress 1 Obesity, Abdominal|Hyperlipidemias|Inflammation|Dysbiosis 1 Impaired Fasting Glucose 1 Human Health|Polyphenols|Pharmacokinetics 1 Healthy Individual 1 Healthy 1 Gastrointestinal Symptoms 1 Diabetes|Cardiovascular Diseases|Prediabetes 1
📋 Sample Trials
NCT02542033
Glycemic Response to Low Sugar Apple Juice
Completed
NCT03846986
Postprandial Glycemia in Apple Products
Completed
NCT02974491
Consumption of Apple Juice in Hemodialysis Patients
Completed
📊 Sample Meta-Analyses
CRD42020215977
Investigation of apple and apple-related products on human health focusing on metabolic disease: a systematic review and meta-analysis
All randomized controlled trial studies investigated the biological effect of th
📚 Sample References
PMID 33037751
Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling
Phytother Res · 2021
PMID 34639090
Quercetin-3-Glucoside Extracted from Apple Pomace Induces Cell Cycle Arrest and Apoptosis by Increasing Intracellular ROS Levels
Int J Mol Sci · 2021
🌿 All Herb data fields for Apple
🌿 Names
Pinyin Name
Ping Guo
中文名 (Chinese)
苹果
Latin Name
Fructus Mali Pumilae
English Name
Apple
Alias Names
柰; 频婆; 柰子; 平波; 超凡子; 天然子; 频果; 西洋苹果
☯ TCM Properties
Properties (性味)
Cool; Sweet; Slightly Sour
Meridians (归经)
Lung; Spleen; Stomach
Part Used
Fruit
🩺 Clinical Profile
Function (功能)
To boost stomach, engender liquid, eliminate vexation, arouse liquor.
Indication (主治)
Scant fluid and thirst, spleen vacuity diarrhea, food retention and abdominal distention, resolve liquor toxin.
🔗 External References
HERB DB
HERB004372 ↗
TCMID
6303
🔍 Raw view — every non-empty column on this row (25 fields)
name
Apple
chinese name
苹果
pinyin name
Ping Guo
latin name
Fructus Mali Pumilae
english name
Apple
properties english
Cool; Sweet; Slightly Sour
meridians english
Lung; Spleen; Stomach
use part
Fruit
tcmid id
6303
herb id str
HERB004372
function text
To boost stomach, engender liquid, eliminate vexation, arouse liquor.
indication
Scant fluid and thirst, spleen vacuity diarrhea, food retention and abdominal distention, resolve liquor toxin.
alias name
柰; 频婆; 柰子; 平波; 超凡子; 天然子; 频果; 西洋苹果

🏥 Linked Health Topics

1 · studied for these conditions (text bridge)
Cardiovascular Diseases
group

📋 Clinical Trials

10 · subject of clinical study
NCT02542033 Glycemic Response to Low Sugar Apple Juice
→ Impaired Fasting Glucose
NCT03846986 Postprandial Glycemia in Apple Products
→ Healthy
NCT02974491 Consumption of Apple Juice in Hemodialysis Patients
→ Oxidative Stress
NCT03523403 Obesity-related Health Benefits of Apples
→ Obesity, Abdominal|Hyperlipidemias|Inflammation|Dy
NCT01585519 A Study Examining Effects of Apples/ Apple Products on Heart Disease Risk
→ Cardiovascular Disease
NCT03911050 Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human
→ Human Health|Polyphenols|Pharmacokinetics
NCT02224365 The Effects of Apple Consumption on Cardiovascular Health in Prediabetics and Ty
→ Diabetes|Cardiovascular Diseases|Prediabetes
NCT03227874 Effects of Dried Apple on Metabolic Responses
→ Healthy Individual
NCT03714464 Effect of Physical Form of Apples on Gastrointestinal Function and Satiety: a MR
→ Gastrointestinal Symptoms
NCT01141803 Effect of Apple and Apple Pomace on Inflammation and Cholesterol Metabolism in H
→ Cardiovascular Diseases

📊 Meta-Analyses

1 · systematic review
CRD42020215977 Investigation of apple and apple-related products on human health focusing on me
→ All randomized controlled trial studies investigat

📚 PubMed References

2 · cited research
PMID 33037751 Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-expose
Phytother Res
PMID 34639090 Quercetin-3-Glucoside Extracted from Apple Pomace Induces Cell Cycle Arrest and
Int J Mol Sci
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables