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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

Uridine

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Uridine

Bipolar Disorder 1 5'-Nucleotidase Syndrome 1 Suicidal Ideation 1 HIV Infections|Insulin Resistance|Hyperlactatemia 1 Healthy Male Subjects 1 Cystic Fibrosis 1 Bipolar Disorder|Bipolar Depression|Manic Depression 1

📋 Sample Trials

NCT00004658

Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involving Excessive 5'-Nucleotidase Activity

Completed · Phase 2

NCT00471614

Effects of Uridine Supplementation on Metabolic Side Effects of Stavudine and Zidovudine

Completed · Phase 2

NCT00841269

Oral Uridine for Treatment of Bipolar Depression in Adolescents

Completed · Phase 2

📊 Sample Meta-Analyses

None linked yet.

📚 Sample References

PMID 36142532

Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet-Streptozotocin-Induced Diabetes

Int J Mol Sci · 2022

PMID 36142572

The Effect of Uridine on the State of Skeletal Muscles and the Functioning of Mitochondria in Duchenne Dystrophy

Int J Mol Sci · 2022

⚗️ All Ingredient data fields for Uridine

⚗️ Identity

Name

Uridine

Aliases / Synonyms

58-96-8; Uridin; Uracil riboside; 1-beta-D-Ribofuranosyluracil; beta-Uridine; Uracil, 1-beta-D-ribofuranosyl-; d-uridine; CHEBI:16704; MFCD00006526

🧪 Chemistry

Molecular Weight

244.2030

LogP

-2.8519

Drug-likeness

0.444

Oral Bioavailability

10.4880

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

Isomeric SMILES

C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

InChIKey

DRTQHJPVMGBUCF-XVFCMESISA-N

InChI

InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

🔗 External References

HERB DB

PubChem CID

CAS Number

DrugBank

NPASS

NPC43246

HIT

C0471

SymMap

TCMID

22236

TCMSP

MOL000059

TCM-ID

258

🔍 Raw view — every non-empty column on this row (35 fields)

name

Uridine

common names

58-96-8; Uridin; Uracil riboside; 1-beta-D-Ribofuranosyluracil; beta-Uridine; Uracil, 1-beta-D-ribofuranosyl-; d-uridine; CHEBI:16704; MFCD00006526

herb ingredient id

HBIN047579

canonical smiles

C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

isomeric smiles

C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

inchi

InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

inchikey

DRTQHJPVMGBUCF-XVFCMESISA-N

mol wt

244.2030

num h acceptors

num h donors

mol logp

-2.8519

num rotatable bonds

drug likeness

0.444

ob score

10.4880

cas id

68184-15-6

symmap mol id

tcmid ingredient id

22236

tcmsp ingredient id

MOL000059

tcm id ingredient id

258

pubchem cid

6029

drugbank id

DB02745

npass id

NPC43246

hit id

C0471

🏥 Linked Health Topics

2 · diseases via target pathways

📋 Clinical Trials

7 · subject of clinical study

NCT00004658 Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involvin

→ 5'-Nucleotidase Syndrome

NCT00471614 Effects of Uridine Supplementation on Metabolic Side Effects of Stavudine and Zi

→ HIV Infections|Insulin Resistance|Hyperlactatemia

NCT00841269 Oral Uridine for Treatment of Bipolar Depression in Adolescents

→ Bipolar Disorder

NCT01261260 Effect of Uridine on GABA and High Energy Phosphate Levels in Healthy Volunteers

→ Healthy Male Subjects

NCT01805440 Uridine Adolescent Bipolar Depression Randomized Controlled Trial

→ Bipolar Disorder|Bipolar Depression|Manic Depressi

NCT03265964 Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

→ Suicidal Ideation

NCT00004705 Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis

→ Cystic Fibrosis

📚 PubMed References

2 · cited research

PMID 36142532 Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in

Int J Mol Sci

PMID 36142572 The Effect of Uridine on the State of Skeletal Muscles and the Functioning of Mi

Int J Mol Sci

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables