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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Vasopressin

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Vasopressin

Critically ill patients 2 post cardiac arrest in adults 2 Hemodynamic instability is a frequent complication in patien 1 Misoprostol Allergy|Oxytocin Allergy|Tranexamic Acid Allergy 1 Septic shock is a life-threatening condition that results fr 1 Heart failure (HF) is associated with impaired quality of li 1 Cardiac Arrest Neonatal 1 Sepsis is a common yet complex disorder that remains one of 1 Sepsis is a “life-threatening organ dysfunction caused by a 1 Critical care medicin 1 Vasopressin in combination with glucocorticoids have been de 1 Sepsis and septic shock are life-threatening conditions with 1

📋 Sample Trials

NCT05738148

Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation

Recruiting · Phase 1

NCT05806307

Methods Decreasing Bleeding in Open Myomectomy

Recruiting · Phase 4

📊 Sample Meta-Analyses

CRD42020178297

Efficacy of Corticosteroids, Vasopressin and Epinephrine combination therapy in patients with post_cardiac arrest: a systematic review of clinical trials

post cardiac arrest in adults

CRD42022296508

Evaluation of the effect of corticosteroids and vasopressin and epinephrine drugs alone or in combination in patients after cardiac arrest in a systematic network review

post cardiac arrest in adults

CRD42013005249

Vasopressin receptor antagonists for the treatment of heart failure

Heart failure (HF) is associated with impaired quality of life, with significant

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Vasopressin

⚗️ Identity

Name

Vasopressin

Aliases / Synonyms

8-L-Lysine vasopressin; Pressyn; 3-(Phenylalanine)-8-lysine oxytocin; BDBM627975; CVD-0019448; Q60496436; 6-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)hexanamide

🧪 Chemistry

Molecular Weight

1056.2390

LogP

-4.3291

Drug-likeness

0.047

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N

Isomeric SMILES

C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N

InChIKey

BJFIDCADFRDPIO-ZCCHBGLBSA-N

InChI

InChI=1S/C46H65N13O12S2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)/t28-,29?,30-,31-,32-,33-,34-,35-/m0/s1

🔗 External References

HERB DB

HBIN047763 ↗

PubChem CID

53477739 ↗

DrugBank

DB00067 ↗

NPASS

NPC240285

TCMID

22337

🔍 Raw view — every non-empty column on this row (29 fields)

name

Vasopressin

common names

herb ingredient id

HBIN047763

canonical smiles

C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N

isomeric smiles

C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N

inchi

inchikey

BJFIDCADFRDPIO-ZCCHBGLBSA-N

mol wt

1056.2390

num h acceptors

num h donors

mol logp

-4.3291

num rotatable bonds

drug likeness

0.047

tcmid ingredient id

22337

pubchem cid

53477739

drugbank id

DB00067

npass id

NPC240285

📋 Clinical Trials

2 · subject of clinical study

NCT05738148 Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation

→ Cardiac Arrest Neonatal

NCT05806307 Methods Decreasing Bleeding in Open Myomectomy

→ Misoprostol Allergy|Oxytocin Allergy|Tranexamic Ac

📊 Meta-Analyses

12 · systematic review

CRD42020178297 Efficacy of Corticosteroids, Vasopressin and Epinephrine combination therapy in

→ post cardiac arrest in adults

CRD42022296508 Evaluation of the effect of corticosteroids and vasopressin and epinephrine drug

→ post cardiac arrest in adults

CRD42013005249 Vasopressin receptor antagonists for the treatment of heart failure

→ Heart failure (HF) is associated with impaired qua

CRD42017067344 Vasopressin as an alternative vasopressor drug in cardiac surgical patients

→ Hemodynamic instability is a frequent complication

CRD42021236094 Efficacy and Safety of Vasopressin and Terlipressin in Preterm Neonates: A Proto

→ In premature neonates of neonatal intensive care u

CRD42017059058 Vasopressin versus catecholaminergic vasopressors in the treatment of vasodilato

CRD42022368373 Efficacy and safety of vasopressin or catecholamines alone or in combination for

→ Sepsis is a “life-threatening organ dysfunction ca

CRD42020208622 Vasopressin or norepinephrine in vasoplegic shock in surgical patients: Systemat

→ Vasoplegia is a common feature of all advanced sho

CRD42018110903 Discontinuation sequence of norepinephrine and vasopressin in septic shock: a me

→ Septic shock is an high mortality related disease

CRD42016035872 Role of vasopressin and terlipressin in catecholamine resistant shock in the neo

→ Pediatric resistant shock.

CRD42017054324 Effect of vasopressin and analogues on renal outcome in distributive shock

→ Shock.

CRD42017071457 A systematic review of vasopressin (antidiuretic hormone, ADH) versus other anti

→ As the average age of the Canadian population incr

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables